To identify morphological features, other than macrovesicular steatosis, that may affect recipients\' outcome.
Between 2014 and 2016, 132 donors with extended criteria underwent pre-transplant liver biopsy during procurement. Histological variables of the graft, donors\'/recipients\' clinical data, EAD and patient/graft survival were registered.
The recipients who received a graft with histological-proven portal fibrosis had a significant lower patient and graft survival in comparison to patients without fibrosis (P = 0.044 and P = 0.039, respectively). Donors\' dyslipidemia was significantly associated with the occurrence of EAD (P = 0.021). When dyslipidemia was combined with histological liver fibrosis a 54.5% incidence of EAD was observed (P = 0.012).
The histological assessment of liver fibrosis in pre-transplant biopsy of ECD grafts, together with donor\'s clinical data, provides important information on recipients\' outcome.