关键词: branch pulmonary artery stenosis children premounted stent

Mesh : Age Factors Databases, Factual Endovascular Procedures / adverse effects instrumentation Female Hemodynamics Humans Infant Male Prosthesis Design Pulmonary Circulation Recovery of Function Retreatment Retrospective Studies Risk Factors Stenosis, Pulmonary Artery / diagnostic imaging physiopathology therapy Stents Time Factors Treatment Outcome

来  源:   DOI:10.1002/ccd.27800

Abstract:
Define outcomes of premounted stent implantation (PMS) for branch pulmonary artery stenosis (BPAS).
PMS for BPAS in children raises concern of long term viability, with limited maximal expansion.
We reviewed our cardiac database over an 11-year period ending in 2013. Primary endpoint was need for surgical stent intervention (SSI). Other endpoints included acute results and repeat interventions (RI).
82 PMS were implanted in 60 children for BPAS. Median weight was 6.3 (25th -75th 4.6-9.8) kg. Median stent diameter was 6 (range 4-9) mm. Acutely, vessel diameter improved from 2.0 (25th -75th 1.6-3.4) to 5.0 (25th -75th 4.2-5.9) mm (p < 0.001), pressure gradient decreased from 41 (25th -75th 29-50) to 11 (25th -75th 7-18) mmHg (n = 47, p < 0.001), RV:Ao pressure ratio decreased from 100% (25th -75th 85-110%) to 59% (25th -75th 49-74%) (n = 40, p < 0.001). Freedom from SSI was 81% at 1 year and 35% at 5 years. Freedom from RI was 50% at 1 year and 14% at 5 years. 86% of PMS underwent SSI during a concomitant planned cardiac surgery. 45% patients had stent redilation, improving stent diameter from 4.6 (25th -75th 4.1-5.4) to 5.7 (25th -75th 4.9-7) mm (p < 0.001). 1 stent (3%) was able to be fractured longitudinally.
PMS is an effective short term solution for BPAS in children. PMS is associated with expected early need for transcatheter reintervention to accommodate for growth, but also has high rates of SSI.
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