关键词: antigen autoimmunity epitope human leukocyte antigen (HLA) preproinsulin proconvertase secretogranin transpeptidation type 1 diabetes urocortin
Mesh : Animals Antigen Presentation Biomarkers / metabolism CD8-Positive T-Lymphocytes / cytology immunology metabolism Case-Control Studies Cell Line Corticotropin-Releasing Hormone / metabolism Cytokines / metabolism Diabetes Mellitus, Type 1 / immunology Epitopes, T-Lymphocyte / immunology HLA Antigens / metabolism Humans Insulin / metabolism Islet Amyloid Polypeptide / metabolism Mice Neuroendocrine Secretory Protein 7B2 / metabolism Proprotein Convertase 2 / metabolism Protein Precursors / metabolism Proteomics / methods Transcriptome / immunology Urocortins / metabolism
来 源:
DOI:10.1016/j.cmet.2018.07.007
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