关键词: coccidioidomycosis imported mycosis voriconazole

Mesh : Adolescent Adult Aged Aged, 80 and over Antifungal Agents / administration & dosage therapeutic use Antitubercular Agents / therapeutic use Child, Preschool China / epidemiology Coccidioidomycosis / diagnosis diagnostic imaging epidemiology microbiology Communicable Diseases, Imported / diagnosis drug therapy epidemiology microbiology Diagnostic Errors Female Humans Lung / diagnostic imaging microbiology Male Middle Aged Tomography, X-Ray Computed Travel Tuberculosis / drug therapy epidemiology microbiology Voriconazole / administration & dosage therapeutic use Young Adult

来  源:   DOI:10.1111/myc.12750

Abstract:
We report a case of imported pulmonary coccidioidomycosis caused by Coccidioides posadasii in a patient who was misdiagnosed as tuberculosis and mistreated with antituberculosis medications for 18 months. The symptoms were not relieved until antifungal treatment was started. An extensive review of the coccidioidomycosis cases occurring in China reveals 38 cases, 16 of which had no associated history of travel to any traditional endemic areas. We speculate that some factors may drive Coccidioides spp. transference to China, which then causes those domestic infections. Moreover, we indicate the first, to the best of our knowledge, possible endemic areas in China.
摘要:
我们报告了一例由球虫引起的进口肺球虫菌病,该患者被误诊为结核病并接受抗结核药物治疗18个月。直到开始抗真菌治疗,症状才缓解。对中国发生的球孢子菌病病例的广泛审查显示38例,其中16个没有前往任何传统流行地区的相关历史。我们推测,一些因素可能会驱动球虫。转移到中国,然后导致这些家庭感染。此外,我们指出第一个,据我们所知,中国可能的流行地区。
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