关键词: FXR1 STAT cancer biology collateral lethality fragile X family mouse p53 deletion
Mesh : Animals Apoptosis / genetics Base Sequence CRISPR-Cas Systems / genetics Cell Line, Tumor Cell Proliferation / genetics Cell Transformation, Neoplastic / genetics Chromatin Female Gene Editing Gene Expression Profiling Gene Expression Regulation, Neoplastic Gene Knockdown Techniques Heterografts Homozygote Humans Janus Kinase Inhibitors / analysis Mice Mice, Inbred BALB C Neoplasms / genetics Promoter Regions, Genetic RNA-Binding Proteins / genetics metabolism STAT1 Transcription Factor / genetics STAT3 Transcription Factor / genetics Sequence Deletion Transcription Factors Tumor Suppressor Protein p53 / genetics
来 源:
DOI:10.7554/eLife.26129
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