法尼醇 X 受体,胆汁酸感应核受体 ,在肝脏再生中。
关键词: ABC, ATP-binding cassette AMPK, AMP-activated protein kinase BA, bile acid Bile acids C/EBPβ, CCAAT-enhancer binding protein β CA, cholic acid CDCA, chenodeoxycholic acid CTX, cerebrotendinous xanthomatosis CYP7A1, cholesterol 7alpha-hydroxylase CYP8B1, sterol 12α-hydroxylase Cyp27-KO, sterol 27-hydroxylase–knockout DDAH-1, dimethylarginineaminohydrolase-1 ERK1/2, extracellular signal-regulated kinase 1/2 FGF-15, fibroblast growth factor 15 FGFR4, FGF receptor 4 FOXM1b, forkhead boxm1b FXR, farnesoid X receptor Farnesoid X receptor Fibroblast growth factor 15 Fxr-KO, Fxr-knockout GPBAR1 or TGR5, G protein-coupled BA receptor 1 HEX, hematopoietically expressed homeobox JNK, c-Jun N-terminal kinase KC, Kupffer cells KO, knockout Liver regeneration Liver-intestine croass talk MAPK, mitogen-activated protein kinase MRP3, multidrug resistance associated protein 3 NASH, nonalcoholic steatohepatitis NF-κB, nuclear factor-κB PH, partial hepatectomy Rb, retinoblastoma SHP, small heterodimer partner STAT3, signal transducer and activator of transcription 3 TH, thyroid hormone THR, TH receptor Transmembrane G protein coupled receptor 5 WT, wild type cAMP, cyclic adenosine monophosphate hepFxr-KO, hepatocyte-specific Fxr knockout
来 源:
DOI:10.1016/j.apsb.2015.01.005
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