PDF(Pubmed)
Abstract：
The cellular abnormalities that lead to diabetic gastroparesis are increasingly being understood. Several key cell types are affected by diabetes, leading to gastroparesis. These changes include abnormalities in the extrinsic innervation to the stomach, loss of key neurotransmitters at the level of the enteric nervous system, smooth muscle abnormalities, loss of interstitial cells of Cajal, and changes in the macrophage population resident in the muscle wall. This article reviews the current understanding with a focus on data from human studies when available.
摘要：
导致糖尿病性胃轻瘫的细胞异常越来越被理解。几种关键的细胞类型受到糖尿病的影响，导致胃轻瘫.这些变化包括胃外神经支配的异常，肠神经系统水平的关键神经递质的损失，平滑肌异常，Cajal间质细胞丢失,以及驻留在肌肉壁上的巨噬细胞数量的变化。本文回顾了当前的理解，重点是来自人类研究的数据。
