{Reference Type}: Journal Article
{Title}: Histologic changes in diabetic gastroparesis.
{Author}: Farrugia G;
{Journal}: Gastroenterol Clin North Am
{Volume}: 44
{Issue}: 1
{Year}: Mar 2015
{Factor}: 3.867
{DOI}: 10.1016/j.gtc.2014.11.004
{Abstract}: The cellular abnormalities that lead to diabetic gastroparesis are increasingly being understood. Several key cell types are affected by diabetes, leading to gastroparesis. These changes include abnormalities in the extrinsic innervation to the stomach, loss of key neurotransmitters at the level of the enteric nervous system, smooth muscle abnormalities, loss of interstitial cells of Cajal, and changes in the macrophage population resident in the muscle wall. This article reviews the current understanding with a focus on data from human studies when available.