关键词: necrobiotic xanthogranuloma periorbital total glucosides of paeonys

Mesh : Dermatologic Agents / isolation & purification therapeutic use Female Glucosides / isolation & purification therapeutic use Humans Middle Aged Necrobiotic Xanthogranuloma / diagnosis drug therapy Paeonia / chemistry Phytotherapy Plant Extracts / isolation & purification therapeutic use Plant Roots Plants, Medicinal Remission Induction Skin / drug effects pathology Treatment Outcome

来  源:   DOI:10.1111/dth.12133   PDF(Sci-hub)

Abstract:
Necrobiotic xanthogranuloma (NXG) is a rare granulomatous condition that is often associated with a paraproteinemia and in some cases multiple myeloma. We report a case of isolated NXG that responded very well to total glucosides of paeony treatment. Characteristic clinical and histological features of NXG are presented, as well as a discussion regarding management and the use of glucosides of paeony. Treatment with total glucosides of paeony is an effective, safe treatment, which avoids the side effects associated with systemic corticosteroid or cytotoxic agent therapy.
摘要:
坏死的黄色肉芽肿(NXG)是一种罕见的肉芽肿,通常与副蛋白血症有关,在某些情况下与多发性骨髓瘤有关。我们报告了一例分离的NXG,对白芍总苷治疗反应非常好。介绍了NXG的特征性临床和组织学特征,以及关于白芍苷的管理和使用的讨论。用白芍总苷治疗是有效的,安全治疗,这避免了与全身性皮质类固醇或细胞毒性剂治疗相关的副作用。
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