关键词: AAR CF CK COX Cardioprotection Cur Curcumin FOXO1 HR IPC IR IRI Ischemia reperfusion LDH LVDP MDA Mitochondrial oxidative damage SDH SIR SIRT1 SIRT1 signaling SOD TTC acetylated-forkhead box O1 area at risk coronary flow creatinine kinase curcumin cytochrome c oxidase heart rate ischemia reperfusion ischemia reperfusion injury ischemic preconditioning lactate dehydrogenase methane dicarboxylic aldehyde silent information regulator 1 simulated ischemia reperfusion succinate dehydrogenase super oxygen dehydrogenases the left ventricular developed pressure triphenyltetrazolium chloride
Mesh : Animals Apoptosis / drug effects Cardiotonic Agents / pharmacology Curcumin / pharmacology In Situ Nick-End Labeling Male Mitochondria / drug effects pathology Myocardial Reperfusion Injury / metabolism Myocytes, Cardiac / metabolism Oxidative Stress / drug effects Rats Rats, Sprague-Dawley Sirtuin 1 / metabolism
来 源:
DOI:10.1016/j.freeradbiomed.2013.07.007
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