背景:有大量证据支持以创伤为中心的认知行为疗法治疗创伤后应激障碍(PTSD)的有效性。然而,目前尚不清楚哪种特定的治疗方法对儿童期性虐待和身体虐待(CSPA)后的PTSD患者最有效.尽管Imaginal曝光(IE)已被证明在治疗PTSD方面非常有效,并且被广泛认为是一种标准方法,图像重新设定(IR)可能更适合CSPA相关的PTSD。IR不仅解决了恐惧,而且还针对与童年适应不良模式相关的其他情绪和认知。初步研究结果表明,与IE相比,IR的辍学率较低,但目前尚无随机对照试验(RCT)评估IR对CSPA相关PTSD的有效性.目的:本文提出了一项研究方案,旨在研究CSPA相关PTSD患者的最佳治疗方法(IE或IR),并探讨治疗成功的预测因素。方法:在我们的研究方案中,我们建议纳入173例患者(IR中N=64,在IE中N=64,在等待列表条件下N=45)。IE和IR的治疗程序将包括16个疗程,每个疗程90分钟,治疗时间为11周。测量发生在基线,在治疗开始时,治疗开始后11周(16次疗程后)和最后一次疗程后26周的随访。混合回归将用于比较测量之前和之后的三种活性条件。结果:本文作为研究方案。结果尚不可用,但将在后续文章中介绍。结论:本研究方案概述了RCT,它将首次提供有关CSPA相关PTSD中IR与IE与对照组的有效性的信息。试验注册:荷兰试验注册NTR4817。2014年9月26日注册。
该研究方案旨在增强对16岁之前发生的儿童性虐待和身体虐待(CSPA)引起的创伤后应激障碍(PTSD)的个体(18岁及以上)的临床治疗。在这个协议中,将系统地比较两种创伤后应激障碍干预措施的疗效-意象重塑(IR)和意象暴露(IE),彼此对抗和对照组。本研究方案的次要目标是研究治疗成功的潜在预测因素,包括诸如补品不动性等因素,解离,心率变异性,自主唤醒的措施,人格障碍,以及治疗联盟的质量。
Background: There is a vast amount of evidence supporting the effectiveness of trauma-focused cognitive-behavioral therapy in treating posttraumatic stress disorder (PTSD). However, it remains unclear which specific treatment is most effective for patients with PTSD following childhood sexual and physical abuse (CSPA). Although Imaginal Exposure (IE) has proven highly effective in treating PTSD and is widely acknowledged as a standard method, Imagery Rescripting (
IR) may be more suitable for CSPA-related PTSD. IR not only addresses fear but also targets other emotions and cognitions associated with childhood maladaptive schemas. Preliminary findings suggest lower drop-out rates for
IR compared to IE, but no Randomized Controlled Trial (RCT) currently assesses the effectiveness of
IR for CSPA-related PTSD.Objective: This article presents a study protocol designed to investigate the optimal treatment (IE or
IR) for individuals with CSPA-related PTSD and explore predictors of treatment success.Method: In our study protocol, we suggest the inclusion of 173 patients (N = 64 in
IR, N = 64 in IE, and N = 45 in the waitlist condition). The therapy procedures for both IE and IR will consist of 16 sessions lasting 90 min each, with treatment durations of 11 weeks. Measurements take place at baseline, at start of treatment, 11 weeks after the start of treatment (after 16 sessions) and at follow-up at 26 weeks after the last session. A mixed regression will be used to compare the three active conditions before and after measurement.Results: This article serves as a study protocol. The results are not yet available but they will be presented in a subsequent article.Conclusion: This study protocol outlines a RCT which will be the first to provide information on the effectiveness of IR versus IE versus a control group in CSPA-related PTSD.Trial registration: Netherlands Trial Register NTR 4817. Registered 26 September 2014.
This study protocol is designed to enhance the clinical treatment for individuals (aged 18 and above) experiencing posttraumatic stress disorder (PTSD) resulting from childhood sexual and physical abuse (CSPA) occurring before the age of 16.Within this protocol, the efficacy of two PTSD interventions – Imagery Rescripting (IR) and Imaginal Exposure (IE) – will be systematically compared, both against each other and a control group.The secondary objective of this study protocol is to investigate potential predictors of treatment success, including factors such as tonic immobility, dissociation, heart rate variability, measures of autonomic arousal, personality disorders, and the quality of therapeutic alliance.