Abstract:
Evidences that demonstrate or imply the occurrence of DNA-RNA viral interactions in man and animals are reviewed. The concurrent presence of two dissimilar oncogenic viruses influenced responses both in vivo and in vitro. Cell-mediated immune responses to Marek\'s disease herpesvirus were altered in specific-pathogen-free chickens inoculated as embryos with an avian leukosis virus. The possible roles of immunological factors in the pathogenesis and control of tumor development associated with DNA-RNA viral interactions remain to be investigated.
摘要:
综述了证明或暗示在人和动物中发生DNA-RNA病毒相互作用的证据。两种不同的致癌病毒的同时存在会影响体内和体外的反应。在接种为禽白血病病毒的无特定病原体的鸡中,对Marek病疱疹病毒的细胞介导的免疫反应发生了变化。免疫因素在与DNA-RNA病毒相互作用相关的肿瘤发生的发病机理和控制中的可能作用仍有待研究。