Mesh : Alendronate / therapeutic use Calcitonin / therapeutic use Calcium / therapeutic use Estrogen Replacement Therapy Etidronic Acid / analogs & derivatives therapeutic use Evidence-Based Medicine Humans Meta-Analysis as Topic Osteoporosis / drug therapy Practice Guidelines as Topic Randomized Controlled Trials as Topic Risedronic Acid Selective Estrogen Receptor Modulators / therapeutic use Vitamin D / therapeutic use Vitamin K 2 / therapeutic use