• 文章类型: Review
    背景:接受凝血障碍治疗的患者数量,更具体地说是抗凝治疗,近年来,由于发达国家的预期寿命增加,在全球范围内有所增加。近年来,在口腔外科手术中管理此类患者的方案各不相同,特别是在新的直接作用口服抗凝剂(DOAC)出现后。对于患者来说,评估此类患者在接受外科手术时的出血风险仍然是一个有争议的问题。牙医和全科医生。本文件的目的是提出建议,基于证据,为需要牙科手术干预的凝血障碍患者做出决策。
    方法:基于国家卫生系统制定临床实践指南的适应症。方法手册\“,我们聚集了一组专家,他们根据在牙科外科手术中管理凝血障碍患者,就15个PICO问题达成一致,如植入物或牙科拔牙的装配。
    结果:根据现有证据回答了15个PICO问题,由于缺乏对照组,在大多数情况下受到限制。其中两个PICO问题由专家以C级建议回答,其余的以D级回答。
    结论:本综述的结果强调需要与对照组和具有代表性的样本量进行精心设计的临床试验。
    BACKGROUND: The number of patients treated with coagulation disorders, and more specifically with anticoagulant therapy, has increased worldwide in recent years due to increased life expectancy in developed countries. The protocols for managing this type of patient in oral surgery has varied over recent years, especially after the appearance of new direct-acting oral anticoagulants (DOACs). The assessment of risk of bleeding in this type of patient when undergoing a surgical procedure continues to be a controversial issue for patients, dentists and general practitioners. The objective of this document is to offer recommendations, based on evidence, for decision making for patients with coagulopathies who require dental surgical intervention.
    METHODS: Based on the indications of the \"Preparation of Clinical Practice guidelines in the National Health System. Methodological manual\", we gathered a group of experts who agreed on 15 PICO questions based on managing patients with coagulation disorders in dental surgical procedures, such as fitting of implants or dental extractions.
    RESULTS: The 15 PICO questions were answered based on the available evidence, being limited in most cases due to the lack of a control group. Two of the PICO questions were answered by the experts with a grade C recommendation, while the rest were answered with grade D.
    CONCLUSIONS: The results of this review highlight the need to undertake well designed clinical trials with control groups and with a representative sample size.
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  • 文章类型: Journal Article
    背景:口腔癌是全球第16种最常见的恶性肿瘤,死亡率很高,五年超过50%,和高发病率。口腔肿瘤治疗的效果是广泛的,有多个层面,因此,了解这些影响并预防它们对于避免与肿瘤治疗相关的口腔病理学增加至关重要,保持病人的生活质量,并提高治疗本身的疗效。
    方法:一组属于牙科领域的专家,塞维利亚大学颌面外科和肿瘤学以及塞维利亚VirgendelRocio大学医院与巴伦西亚大学合作,巴塞罗那大学,巴斯克大学,制定了本临床实践指南,用于对诊断为口腔癌的患者进行适当的临床管理。临床问题以PICO格式制定。咨询的数据库是Medline/PubMed和Embase/Elsevier。在Tripdatabase上确定了有关该主题的系统评论,Cochrane图书馆和CRD(审查和传播中心)。这些建议是根据GRADE方法编写的。
    结果:定义了各种建议,源自21个PICO问题,关于预防,治疗和护理因口腔癌本身的病理学及其治疗而引起的改变。
    结论:本临床实践指南的编制允许根据现有的科学证据提出建议,关于口腔癌患者和接受肿瘤治疗的牙科行动,这可能对治疗这类患者的多学科团队有用。
    BACKGROUND: Oral cancer is the sixteenth most common malignant neoplasm worldwide, with a high mortality rate, greater than 50% at five years, and high morbidity. The effect of oncological treatment in the oral cavity is broad and has multiple levels, therefore knowing these effects and preventing them is essential for avoiding an increase in the oral pathology related with oncological therapy, maintaining the quality of life of the patient, and improving the efficacy of the treatment itself.
    METHODS: A group of experts belonging to the fields of Dentistry, Maxillofacial Surgery and Oncology of the University of Seville and the Virgen del Rocío University Hospital of Seville in collaboration with the University of Valencia, University of Barcelona, and University of the Basque Country, developed this Clinical Practice Guideline for the proper clinical management of patients diagnosed with oral cancer. The clinical questions were formulated in PICO format. The databases consulted were Medline/PubMed and Embase/Elsevier. The systematic reviews published on the topic were identified on Tripdatabase, Cochrane Library and CRD (Centre for Reviews and Dissemination). The recommendations were prepared based on the GRADE methodology.
    RESULTS: Various recommendations were defined, derived from the 21 PICO questions, referring to prevention, treatment and care for alterations arising from the pathology of oral cancer itself and its treatment.
    CONCLUSIONS: The preparation of this clinical practice guideline allows recommendations to be generated based on the scientific evidence available, on dentistry actions in patients with oral cancer and undergoing oncological treatment, which may be of use to the multidisciplinary team treating this type of patient.
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  • 文章类型: Journal Article
    The coronavirus pandemic (COVID-19) has impacted essentially every country\'s healthcare system in extraordinary ways, fundamentally changing the way we deliver care. The practice of oral and maxillofacial surgery is no exception. In response to this global health crisis, the Saudi Society of Oral and Maxillofacial Surgery has prepared this consensus statement to inform our clinical and other medical colleagues and the public at large on proper procedures during this time. The statement is based on the best scientific evidence available and follows the guidelines put forth by the Saudi Ministry of Health on the COVID-19 response. It explains how to manage and triage oral and maxillofacial patients based on the level of care needed at the time of clinical presentation.
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  • 文章类型: Journal Article
    2019年冠状病毒病的出现(COVID-19),由SARS-CoV-2(SC2)病毒引起,2019年12月下旬给全国的医疗机构带来了压倒性的压力。现代医疗系统从未管理过如此大规模的流行病,其后果无疑将导致病毒测试指南的政策和协议制定的持久变化,个人防护装备(PPE),手术时间安排,以及住院医师教育和培训。华盛顿州是美国首例报告的与COVID-19有关的病例和死亡病例。口腔颌面外科医生有暴露于SC2和发展为COVID-19的独特风险,因为我们在口咽和鼻咽及其周围工作。本报告总结了COVID-19指南在4个关键领域的演变:1)术前SC2测试;2)PPE管理;3)手术安排指南;4)华盛顿大学口腔颌面外科住院医师教育和培训,西雅图,华盛顿。
    The emergence of coronavirus disease 2019 (COVID-19), caused by the SARS-CoV-2 (SC2) virus, in late December 2019 has placed an overwhelming strain on healthcare institutions nationwide. The modern healthcare system has never managed a pandemic of this magnitude, the ramifications of which will undoubtedly lead to lasting changes in policy and protocol development for viral testing guidelines, personal protective equipment (PPE), surgical scheduling, and residency education and training. The State of Washington had the first reported case and death related to COVID-19 in the United States. Oral and maxillofacial surgeons have a unique risk of exposure to SC2 and developing COVID-19 because of our proximity of working in and around the oropharynx and nasopharynx. The present report has summarized the evolution of COVID-19 guidelines in 4 key areas: 1) preoperative SC2 testing; 2) PPE stewardship; 3) surgical scheduling guidelines; and 4) resident education and training for oral and maxillofacial surgery at the University of Washington, Seattle, Washington.
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  • 文章类型: Practice Guideline
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  • 文章类型: Practice Guideline
    专门从事口腔健康的医疗和非医疗从业人员感染冠状病毒-19(新冠肺炎)的风险很高,因为它们与可能感染的生物液体接近。这种风险是永久的,尤其是在考试期间,患者的护理和转移。关于新冠肺炎的大流行进展,迫切需要有效的预防方案。根据我们的经验和法国国家公共卫生机构最近报告的指南(ARS,2020年3月5日),法国医院卫生学会(SFHH,2020年3月4日)和巴黎医院感染风险预防部门-公共援助(APHP,2020年3月6日),我们为专门从事口腔健康的医生提供了一些建议,为了保护自己免受医院感染,尤其是Covid-19.
    Medical as well as non-medical practitioners specialized in oral health are at high risk of infection with the Coronavirus-19 (Covid-19) because of the proximity with potentially infected biological fluids. This risk is permanent, especially during examination, care and transfer of patients. Regarding the pandemic progression of Covid-19, efficient protocols of prevention are urgently needed. Based on our experience and on the recently reported guidelines from the French National Agency for Public Health (ARS, March 5, 2020), the French Society of Hospital Hygiene (SFHH, March 4, 2020) and the Department of Infectious Risk Prevention of the Hospitals of Paris-Public Assistance (APHP, March 6, 2020), we provide several recommendations for practitioners specialized in oral health, to protect themselves from nosocomial infections, especially Covid-19.
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  • 文章类型: Journal Article
    感染性心内膜炎(IE)是一种高死亡率的破坏性疾病。大多数指南建议在口腔手术期间常规使用抗生素预防,以预防患有特定易感心脏病的患者的IE。但在英国情况并非如此。相互矛盾的意见和指导令人困惑,可能会影响IE预防实施。我们调查了如何在口腔颌面外科的医院和门诊中定义IE预防标准。一项调查已发送给德国口腔颌面外科的80名外科医生。我们观察到诊所之间IE预防实施的显着异质性。这种多样性与诱发性心脏病的定义有关,需要IE预防的牙科和外科手术类型,所用化合物的光谱,以及抗生素预防的时机。我们观察到高危患者IE预防的处方不足,非IE高风险患者过度使用抗生素预防,以及使用不适当的药物。这些发现表明,需要教育策略和指南实施建议来提高口腔颌面外科诊所的IE预防标准。
    Infective endocarditis (IE) is a devastating disease with high mortality. Most guidelines recommend routine use of antibiotic prophylaxis during oral surgery to prevent IE in patients with specific predisposing cardiac conditions, but this is not the case in the UK. The conflicting opinions and guidance are confusing and may affect IE prophylaxis implementation. We investigated how IE prophylaxis standards are defined in hospitals and outpatient clinics of oral and maxillofacial surgery. A survey was sent to 80 surgeons heading departments of oral and maxillofacial surgery in Germany. We observed significant heterogeneity in IE prophylaxis implementation among the clinics. This diversity was in relation to the definition of predisposing cardiac conditions, the type of dental and surgical procedures performed that require IE prophylaxis, the spectrum of compounds used, and the timing of antibiotic prophylaxis. We observed under-prescription of IE prophylaxis in high-risk patients, the overuse of antibiotic prophylaxis in patients not at high risk of IE, and the use of inappropriate drugs. These findings suggest that educational strategies and guideline implementation advice are needed to improve standards of IE prophylaxis in oral and maxillofacial surgery clinics.
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  • 文章类型: Journal Article
    缺乏对口腔颌面外科临床实践指南质量的评估。这项调查的目的是使用RIGHT(健康护理实践指南的报告项目)清单评估指南的质量。主要结果是根据RIGHT检查表评估指南的得分(质量)并确定预测因子(区域,type,单中心或多中心,和专业/非专业)影响质量分数。在这次审查中,在搜索电子数据库和国家社会网站之后,2名评估员根据22项RIGHT核对表对总共25条指南进行了独立评估.评估者间的可靠性进行了评估。报告与限制有关的项目的缺陷,资金,利益申报和管理,医疗保健问题,质量保证是显而易见的。指南的中位总分为28分(范围14-66)。由多个中心(β=57.15,95%置信区间-26.62至87.68,P=0.001,多变量分析)和非专业协会(β=20,95%置信区间-0.03至40.03,P=0.05,单变量分析)产生的指南倾向于具有更高的质量评分。总的来说,口腔颌面外科使用的临床实践指南的质量被认为是次优的.如果将临床实践指南用于为患者做出治疗决定,临床医生应该意识到其可能的局限性.
    An assessment of the quality of oral and maxillofacial surgery clinical practice guidelines is lacking. The aim of this investigation was to assess the quality of guidelines using the RIGHT (Reporting Items for practice Guidelines in HealThcare) checklist. The primary outcome was to assess the score (quality) of guidelines based on the RIGHT checklist and to identify predictors (region, type, single or multi-centre, and speciality/non-speciality) influencing the quality score. In this review, following a search of electronic databases and national society websites, a total of 25 guidelines were independently assessed by two assessors against the 22-item RIGHT checklist. Inter-assessor reliability was assessed. Deficiencies in the reporting of items relating to limitations, funding, declaration and management of interests, healthcare questions, and quality assurance were evident. The median overall score for the guidelines was 28 (range 14-66). Guidelines produced by multiple centres (β=57.15, 95% confidence interval -26.62 to 87.68, P= 0.001, multivariate analysis) and non-speciality societies (β=20, 95% confidence interval -0.03 to 40.03, P=0.05, univariate analysis) tended to have higher quality scores. Overall, the quality of clinical practice guidelines used in oral and maxillofacial surgery was deemed suboptimal. If clinical practice guidelines are to be used in making treatment decisions for patients, clinicians should be aware of their possible limitations.
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  • 文章类型: Journal Article
    The purpose of this study was to evaluate current state of authorship, financial disclosures, and conflicts of interest in position papers published by the American Association of Oral and Maxillofacial Surgeons (AAOMS).
    This is a cross-sectional review of the position papers published by the AAOMS from 2013 to 2017. Primary outcome variables include position papers published by the AAOMS. Secondary outcome variables include declaration of authorship, financial disclosures, and financial payments. The Open Payments Database for financial disclosures was reviewed for the year the position paper was published and the immediate preceding year.
    Ten position papers were published by the AAOMS from 2013 to 2017. Of the 10 papers, authorship was listed in 3, and none explicitly addressed the presence or absence of financial disclosures or conflicts of interest. Contributors to 3 of the 3 authored papers were found at review of the Open Payments Database to have received industry funding in the year the position paper was published and the immediate preceding year. The remuneration ranged from less than $1,000 to $554,006.02.
    Position papers published by the AAOMS lack standardization for authorship and statements on potential financial disclosure. The authors suggest full disclosures of authorship and authors\' conflicts of interest should be stated on all position papers to provide transparency to the process.
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  • 文章类型: Journal Article
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