• 文章类型: Journal Article
    背景:在新生儿肠道手术中已经达成了儿科手术后增强恢复(ERAS)的共识,然而,它并没有广泛用于儿科泌尿科。我们调查了ERAS指南在儿科泌尿外科的应用,并根据支持儿童ERAS方案的现有证据水平确定其效果。
    方法:进行了系统的文献综述,包括一系列提供采用小儿泌尿外科快速康复方案的文献综述。主要结局指标是研究特征,坚持19个ERAS项目,并发症发生率和住院时间。按手术类型(尿道下裂与大手术)进行亚组分析。
    结果:包括来自1272例外科儿科病例的9个系列数据。67.3%的报告采用了增强的回收途径。两个系列包括接受尿道下裂修复的患者,ERAS项目报告不足。包括接受重大手术的儿童在内的研究提到了15个ERAS项目的中位数,但应用的中位数为11个项目。中位依从率为88.9%(范围50-100)。在最近发表的研究中,更多的ERAS指南项目被报道(应用或提及)。
    结论:在泌尿外科手术中,特别是在尿道下裂修复中,ERAS指南的报告和使用有限;而在儿童大手术中,坚持和遵守率差异很大。在最近的系列中,提到和应用的ERAS项目有所增加。需要未来的研究来确定障碍并克服障碍,以便充分利用ERAS途径并从中受益。
    BACKGROUND: Consensus for Enhanced Recovery After Surgery (ERAS) in pediatrics has been achieved in neonatal intestinal surgery, yet it is not widely utilized in pediatric urology. We investigated the application of ERAS guidelines in pediatric urology, and determined its effects given the available level of evidence supporting the ERAS protocol in children.
    METHODS: A systematic literature review including series providing adoption of fast-track recovery protocols for pediatric urology procedures was carried out. Main outcome measures were study characteristics, adherence to the 19 ERAS items, complication rates and length of hospital stay. Sub-group analysis by surgery type (hypospadias versus major surgery) was performed.
    RESULTS: Nine series with data from 1272 surgical pediatric cases were included. An enhanced recovery pathway was applied in 67.3% of the reports. Two series included patients undergoing hypospadias repair and ERAS items were insufficiently reported. Studies including children undergoing major procedures mentioned a median of 15 ERAS items, yet applied a median of 11 items. Median compliance rate was 88.9% (range 50-100). More ERAS guideline items were reported (applied or mentioned) in the most recently published studies.
    CONCLUSIONS: There is limited reporting and use of the ERAS guidelines in urologic surgery particularly in hypospadias repair; whilst in major surgery in children, adherence and compliance rates vary widely. In more recent series there was an increase in ERAS items that have been mentioned and applied. Future research is needed to identify barriers and to overcome them in order to fully adopt and benefit from the ERAS pathway.
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  • 文章类型: Journal Article
    目的:评价国内外胰腺围手术期加速康复指南的质量,为临床实践提供参考和借鉴。
    方法:在指南网站中系统检索,专业协会网站和数据库,比如最新的,BMJ最佳实践,PubMed,Embase,科克伦图书馆,WebofScience,中国国家知识基础设施(CNKI),万方数据,中国科技期刊数据库(VIP),中国生物医学光盘(CBMdisc),Medlive,准则国际网络(GIN),国家准则信息交换所(NGC),国家健康与护理卓越研究所(NICE),安大略省注册护士协会(RNAO),苏格兰校际指南网络(SIGN),乔安娜·布里格斯研究所图书馆(JBI),包括截至2023年12月20日发布的关于增强胰腺手术后恢复的指南和专家共识。四个评估员应用了“研究与评估指南II”(AGREEII)工具来评估指南的质量。
    结果:这项研究包括七个指南,所有这些在质量方面都被评为B级,ICC系数范围从0.752到0.884,表明一致性很高。
    结论:将来制定指南时,建议使用AGREEII作为参考,强调指南开发过程和方法的标准化,充分考虑患者的价值观和偏好,注重准则的适用性,并努力创造高质量的循证建议。
    OBJECTIVE: To evaluate the quality of guidelines on the pancreatic perioperative enhanced recovery after surgery both domestically and internationally, providing reference and reference for clinical practice.
    METHODS: Systemically retrieved in the guideline websites, professional association websites and databases, such as up to date, BMJ Best Practice, PubMed, Embase, The Cochrane Library, Web of Science, China National Knowledge Infrastructure (CNKI), Wan Fang Data, China Science and Technology Journal Database(VIP), China Biology Medicine disc (CBMdisc), Medlive, Guidelines International Network(GIN), National Guideline Clearinghouse(NGC), National Institute for Health and Care Excellence(NICE), Registered Nurses Association of Ontario(RNAO), Scottish Intercollegiate Guidelines Network(SIGN), Joanna Briggs Institute Library(JBI), including guidelines and expert consensus on enhanced postsurgical recovery in pancreatic surgery published as of December 20, 2023. The Appraisal of Guidelines for Research and Evaluation II(AGREE II) tool was applied to evaluate the quality of the guidelines by four assessors.
    RESULTS: This study included seven guidelines, all of which were rated as Grade B in terms of quality, with ICC coefficients ranging from 0.752 to 0.884, indicating a high level of consistency.
    CONCLUSIONS: When formulating guidelines in the future, it is recommended to use AGREE II as a reference, emphasizing the standardization of the guideline development process and methods, fully considering patients\' values and preferences, focusing on the applicability of the guidelines, and striving to create high-quality evidence-based recommendations.
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  • 文章类型: Journal Article
    尚未完成对探索增强术后恢复(ERAS)指南结果的证据的全面审查。
    为了评估ERAS指南是否与改善住院时间相关,医院再入院,并发症,和死亡率与常规手术治疗相比,并了解基于研究和患者因素的估计差异。
    MEDLINE,Embase,护理和相关健康文献的累积指数,和CochraneCentral从一开始就被搜索到2021年6月。
    标题,摘要,全文由两名独立审稿人筛选。符合条件的研究是随机临床试验,与对照组相比,检查了ERAS引导的手术,并报告了至少1个结果。
    使用标准化数据抽象表单对数据进行一式两份的抽象。该研究遵循了系统评价和荟萃分析的首选报告项目。使用Cochrane偏差风险工具重复评估偏差风险。随机效应荟萃分析用于汇集每个结果的估计值,元回归确定了每个结果中异质性的来源。
    主要结果是住院时间,出院后30天内再次入院,术后30天并发症,和术后30天死亡率。
    在确定的12047个参考文献中,1493个全文进行了资格筛选,495人被纳入系统评价,和74个RCTs,9076名参与者被纳入荟萃分析.纳入的研究提供了来自21个国家和9个ERAS引导的外科手术的数据,其中15个(20.3%)具有低偏倚风险。ERAS合规性的平均值(SD)报告,结果,要素研究清单得分为13.5(2.3)。住院时间减少1.88天(95%CI,0.95-2.81天;I2=86.5%;P<.001),并发症风险降低(风险比,ERAS组0.71;95%CI,0.59-0.87;I2=78.6%;P<.001)。再入院和死亡率的风险并不显著。
    在此荟萃分析中,ERAS指南与住院时间减少和并发症相关。未来的研究应旨在改善ERAS的实施并增加指南的覆盖范围。
    UNASSIGNED: A comprehensive review of the evidence exploring the outcomes of enhanced recovery after surgery (ERAS) guidelines has not been completed.
    UNASSIGNED: To evaluate if ERAS guidelines are associated with improved hospital length of stay, hospital readmission, complications, and mortality compared with usual surgical care, and to understand differences in estimates based on study and patient factors.
    UNASSIGNED: MEDLINE, Embase, Cumulative Index to Nursing and Allied Health Literature, and Cochrane Central were searched from inception until June 2021.
    UNASSIGNED: Titles, abstracts, and full-text articles were screened by 2 independent reviewers. Eligible studies were randomized clinical trials that examined ERAS-guided surgery compared with a control group and reported on at least 1 of the outcomes.
    UNASSIGNED: Data were abstracted in duplicate using a standardized data abstraction form. The study followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses. Risk of bias was assessed in duplicate using the Cochrane Risk of Bias tool. Random-effects meta-analysis was used to pool estimates for each outcome, and meta-regression identified sources of heterogeneity within each outcome.
    UNASSIGNED: The primary outcomes were hospital length of stay, hospital readmission within 30 days of index discharge, 30-day postoperative complications, and 30-day postoperative mortality.
    UNASSIGNED: Of the 12 047 references identified, 1493 full texts were screened for eligibility, 495 were included in the systematic review, and 74 RCTs with 9076 participants were included in the meta-analysis. Included studies presented data from 21 countries and 9 ERAS-guided surgical procedures with 15 (20.3%) having a low risk of bias. The mean (SD) Reporting on ERAS Compliance, Outcomes, and Elements Research checklist score was 13.5 (2.3). Hospital length of stay decreased by 1.88 days (95% CI, 0.95-2.81 days; I2 = 86.5%; P < .001) and the risk of complications decreased (risk ratio, 0.71; 95% CI, 0.59-0.87; I2 = 78.6%; P < .001) in the ERAS group. Risk of readmission and mortality were not significant.
    UNASSIGNED: In this meta-analysis, ERAS guidelines were associated with decreased hospital length of stay and complications. Future studies should aim to improve implementation of ERAS and increase the reach of the guidelines.
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  • 文章类型: Journal Article
    这项研究的目的是评估减肥手术(ERABS)后增强恢复的适应方案对结局的影响。这是一项单中心观察性研究,比较了根据ERABS方案(2022年3月至5月)和旧方法(2021年1月至2022年2月)的对照组的患者。完全正确,253名减肥患者被纳入研究组(n=68)和对照组(n=185)。患者大多为女性(57.3%vs70.2%;p=0.053),平均年龄38.8岁,体重指数41±6.53vs.研究组和对照组为44.60±7.37kg/m2(p=0.007),分别。大多数(90.5%)接受了原发性减肥手术。适应的ERABS协议依从性为98.5%。研究组住院时间较短(平均2.86±0.51vs.4.03±0.28天;p<0.001),相似的总比率(3%与2.7%,p=0.92)和主要并发症(1.5%vs.0,p=0.10)。再入院率相似(1.5%vs1.6%,p=0.92)。仅适用于研究组,早期下床活动(p<0.001),阿片类药物限制,预防术后恶心和呕吐(PONV),获得了满意的评分(视觉模拟总评分平均1.93±0.80,吗啡毫克当量34.0±14.5,PONV总评分平均0.17±0.36).总之,实施适应的ERABS指南改善了患者的术后护理,提高对疼痛管理的认识。在没有安全妥协的情况下缩短了停留时间。放弃老派惯例的努力似乎是值得的,即使部分实施了ERABS。
    The aim of this study is to evaluate the effects of an adapted protocol of enhanced recovery after bariatric surgery (ERABS) on outcomes. This is a single-center observational study comparing patients managed according to adapted ERABS protocol (March-May 2022) with a control group of old method (January 2021-February 2022). Totally, 253 bariatric patients were included in the study (n = 68) and control (n = 185) groups. Patients were mostly females (57.3% vs 70.2%; p = 0.053), of mean age 38.8 years and body mass index 41 ± 6.53 vs. 44.60 ± 7.37 kg/m2 (p = 0.007) in study and control groups, respectively. The majority (90.5%) underwent primary bariatric surgery. Adapted ERABS protocol compliance was 98.5%. The study group had shorter hospital stay (mean 2.86 ± 0.51 vs. 4.03 ± 0.28 days; p < 0.001), similar rates of total (3% vs. 2.7%, p = 0.92) and major complications (1.5% vs. 0, p = 0.10). Readmission rates were similar (1.5% vs 1.6%, p = 0.92). Applied only in the study group, early ambulation (p < 0.001), opioid restriction, and preventing postoperative nausea and vomiting (PONV), resulted in satisfactory scores (mean total visual analogue score 1.93 ± 0.80, morphine milligram equivalent 34.0 ± 14.5, and mean total PONV grade 0.17 ± 0.36). In conclusion, implementing adapted ERABS guidelines improved patients\' postoperative care, raising awareness to pain management. Length of stay was shortened without safety compromise. Efforts to abandon old-school routines seem worthwhile, even if ERABS is partially implemented.
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  • 文章类型: Journal Article
    西班牙肝移植学会(LaSociedadEspañoladeTrasplanteHpático)的目标是通过多学科方法促进和创建有关肝移植当前主题的共识文件。为此,2022年11月,第十次共识文件会议召开,来自26个授权的西班牙肝移植项目的专家参与。本版讨论了肝移植后增强的恢复,将需要的行动分为三个阶段:术前,术中和术后。描述了每个主题的评估证据和共识结论。
    The goal of the Spanish Society for Liver Transplantation (La Sociedad Española de Trasplante Hepático) is to promote and create consensus documents about current topics in liver transplantation with a multidisciplinary approach. To this end, in November 2022, the 10th Consensus Document Meeting was held, with the participation of experts from the 26 authorized Spanish liver transplantation programs. This edition discusses Enhanced Recovery After Liver Transplantation, dividing needed actions into three periods: preoperative, intraoperative and postoperative. The evaluated evidence and the consensus conclusions for each of these topics are described.
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  • 文章类型: Letter
    暂无摘要。
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  • 文章类型: Systematic Review
    背景:全球,ERAS®Society指南开创了围手术期护理的新纪元。本系统评价的目的是比较ERAS®Society腹部和胸外科(ATS)指南中已发布的核心要素和药物治疗建议。确定药理学核心项目是否存在共识将使类似手术的未来指南准备更加标准化,并可以通过减少不必要的方案变化来改善患者护理。
    方法:从ERAS®Society网站截至2023年5月,分析中纳入了16项当前ERAS®发布的ATS指南,以确定关于每个ERAS®围手术期和药物治疗相关项目的共识和不同陈述。目的是(a)确定是否可以就每个项目达成共识,(b)确定ERAS®协议开发中的差距,(c)提出潜在的研究方向,以解决文献中已查明的差距。
    结果:达成共识的核心项目包括:术前戒烟和戒酒;避免肠道修复和禁食;多模式麻醉前,围手术期镇痛,和术后恶心和呕吐方案;低分子量肝素用于住院和家中静脉血栓栓塞预防;抗生素预防;皮肤准备;平衡晶体的目标指导围手术期液体管理;围手术期营养护理;外周作用μ受体拮抗剂预防肠梗阻;和血糖控制。
    结论:虽然在与药物治疗选择相关的21项当前ERAS®指南核心项目方面达成共识,有关剂量的细节,方案,给药时机以及与特定手术相关的独特方面仍有待研究和协调,以促进指南一致性并进一步优化患者结局.
    Worldwide, ERAS® Society guidelines have ushered in a new era of perioperative care. The purpose of this systematic review is to compare published core elements and pharmacotherapy recommendations embedded within ERAS® Society abdominal and thoracic surgery (ATS) guidelines. Determining whether a consensus exists for pharmacological core items would make future guideline preparation for similar surgeries more standardized and could improve patient care by reducing unnecessary protocol variations.
    From the ERAS® Society website as of May 2023, 16 current ERAS® published ATS guidelines were included in the analysis to determine consensus and differing statements regarding each ERAS® perioperative and pharmacotherapy-related item. The aims were to (a) determine whether a consensus for each item could be derived, (b) identify gaps in ERAS® protocol development, and (c) propose potential research directions for addressing the identified gaps in the literature.
    Core items with consensus included: preoperative smoking and alcohol cessation; avoiding bowel reparation and fasting; multimodal preanesthetic, perioperative analgesia, and postoperative nausea and vomiting regimens; low molecular weight heparins for in-hospital and at-home venous thromboembolism prophylaxis; antibiotic prophylaxis; skin preparation; goal-directed perioperative fluid management with balanced crystalloids; perioperative nutrition care; ileus prevention with peripherally-acting mu receptor antagonists; and glucose control.
    While consensus was found for aspects of 21 current ERAS® guideline core items related to pharmacotherapy choice, details related to doses, regimen, timing of administration as well as unique aspects pertaining to specific surgeries remain to be researched and harmonized to promote guideline consistency and further optimize patient outcomes.
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  • 文章类型: Practice Guideline
    西班牙肝移植学会(SociedadEspañoladeTrasplanteHeptico)的目标是通过多学科方法促进和创建有关肝移植当前主题的共识文件。为此,2022年11月,第十次共识文件会议召开,来自26个授权的西班牙肝移植项目的专家参与。本版讨论了肝移植后增强的恢复,将需要的行动分为3个时期:术前,术中和术后。描述了每个主题的评估证据和共识结论。
    The goal of the Spanish Society for Liver Transplantation (Sociedad Española de Trasplante Hepático) is to promote and create consensus documents about current topics in liver transplantation with a multidisciplinary approach. To this end, in November 2022, the 10th Consensus Document Meeting was held, with the participation of experts from the 26 authorized Spanish liver transplantation programs. This edition discusses enhanced recovery after liver transplantation, dividing needed actions into 3periods: preoperative, intraoperative and postoperative. The evaluated evidence and the consensus conclusions for each of these topics are described.
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  • 文章类型: Journal Article
    背景:目前,减重手术是治疗病态肥胖最有效的方法。它提供了持续的体重减轻以及对肥胖相关的合并症的积极影响。在过去的二十年中,全世界执行的程序数量急剧增加。因此,在基于最佳证据的围手术期护理方面达成共识的努力.
    方法:捷克外科学会和捷克肥胖症学会联合减重和代谢外科部门的工作组为减重手术围手术期护理中的ERAS(手术后加速恢复)概念制定了临床实践指南。工作组的准则基于2021年发布的ERAS准则。工作组通过了原始案文,然后修改了案文,并酌情对具体项目添加了评论。工作组所有成员的电子投票是最后阶段,就准则的个别要素表达了协商一致的力量。
    结果:捷克工作组就大多数元素与ERABS(减重手术后增强恢复)指南达成了共识。对于减重手术的ERAS方案的某些干预措施,证据质量较低。因此,基于证据的实践需要从其他手术和领域推断。
    结论:本指南旨在根据最新的证据和指南使用ERAS方案进行减肥手术的临床实践。它是基于最近和全面的ERAS指南,由捷克外科学会和捷克肥胖学会联合减肥和代谢外科部门的捷克工作组通过和改编。一些补充和规范反映在捷克语版本的评论中。
    Currently, bariatric surgery is the most effective treatment for the morbid obesity. It provides sustained weight loss as well as demonstrated positive effects on obesity-related comorbidities. The number of procedures performed worldwide has seen a sharp increase in the past twenty years. Therefore, an effort has been developed to establish a consensus in perioperative care based on best evidence.
    The working group of the Joint Bariatric and Metabolic Surgery Section of the Czech Surgery Society and Czech Society of Obesitology prepared clinical practice guidelines for the ERAS (enhanced recovery after surgery) concept in perioperative care in bariatric surgery. The working group based its guidelines on ERAS guidelines published in 2021. The working group adopted the original text and then adapted the text and added its comments to specific items as appropriate. Electronic voting of all members of the working group was the final phase, by which the strength of consensus was expressed with respect to individual elements of the guidelines.
    The Czech working group reached a consensus with ERABS (enhanced recovery after bariatric surgery) guidelines for most elements. The quality of evidence is low for some interventions of the ERAS protocol for bariatric surgery. Therefore, extrapolation from other surgeries and fields is needed for evidence-based practice.
    The guidelines are intended for clinical practice in bariatric surgery with the ERAS protocol based on updated evidence and guidelines. It is based on recent and comprehensive ERAS guidelines adopted and adapted by the Czech working group of the Joint Bariatric and Metabolic Surgery Section of the Czech Surgery Society and Czech Society of Obesitology. Some supplementations and specifications are reflected in comments added to the Czech version.
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  • 文章类型: Practice Guideline
    增强手术后恢复(ERAS)计划已被证明可以减轻手术损伤,促进复苏,并改善许多专业手术的术后临床结果。ERAS的核心原则涉及提供基于协议的循证围手术期干预措施。考虑到将ERAS原则应用于心脏手术的热情日益高涨,以及相关干预措施的广泛范围,一个国际,组建了多学科专家小组,以得出潜在的计划要素清单,回顾文献,并提供有关每个主题领域的临床实践的声明。本文总结了这些共识声明及其附带证据。这些结果为接受心脏手术的成年患者的管理提供了最佳实践基础。
    Enhanced Recovery After Surgery (ERAS) programs have been shown to lessen surgical insult, promote recovery, and improve postoperative clinical outcomes across a number of specialty operations. A core tenet of ERAS involves the provision of protocolized evidence-based perioperative interventions. Given both the growing enthusiasm for applying ERAS principles to cardiac surgery and the broad scope of relevant interventions, an international, multidisciplinary expert panel was assembled to derive a list of potential program elements, review the literature, and provide a statement regarding clinical practice for each topic area. This article summarizes those consensus statements and their accompanying evidence. These results provide the foundation for best practice for the management of the adult patient undergoing cardiac surgery.
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