■COVID-19心血管后遗症的先前研究包括在4周内进行的诊断,但世界卫生组织对“急性期”的定义是>3个月。
■这项研究的目的是确定COVID-19急性期哪些心血管诊断与SARS-CoV-2感染有关。
■对艾伯塔省所有在2020年3月1日至2021年6月30日之间SARS-CoV-2逆转录聚合酶链反应测试阳性的成年人进行的回顾性队列研究,匹配(按年龄,性别,Charlson合并症评分,和测试日期)与逆转录聚合酶链反应测试阴性的对照。
■177892例实验室确认SARS-CoV-2感染的患者(平均年龄42.7岁,49.7%的女性)更有可能去急诊室(5.7%对3.3%),住院(3.4%vs2.1%),或在1个月内死亡(1.3%vs0.4%)比匹配的测试阴性对照。三个月后,病例比对照组更有可能因糖尿病进行急诊就诊或住院(1.5%vs0.7%),高血压(0.6%vs0.4%),心力衰竭(0.2%vs0.1%),或肾损伤(0.3%对0.2%)。在6,030例因COVID-19住院后存活的患者中,急性期糖尿病的风险明显更高(9.5%vs3.0%,调整后的赔率比[AOR]:3.16[95%CI:2.43-4.12]),高血压(3.5%vs1.4%,OR:2.89[95%CI:1.97-4.23]),心力衰竭(2.1%vs0.7%,OR:3.16[95%CI:1.88-5.29]),肾损伤(3.1%对0.8%,OR:2.70[95%CI:1.71-4.28]),出血(1.5%vs0.5%,OR:3.40[95%CI:1.83-6.32]),和静脉血栓栓塞(0.8%vs0.3%,OR:3.60[95%CI:1.59-8.13])。
■临床医生应该对COVID-19幸存者进行糖尿病筛查,高血压,心力衰竭,和急性期的肾功能障碍。
UNASSIGNED: Prior studies of COVID-19 cardiovascular sequelae include diagnoses made within 4 weeks, but the World Health Organization definition for \"postacute phase\" is >3 months.
UNASSIGNED: The purpose of this study was to determine which cardiovascular diagnoses in the postacute phase of COVID-19 are associated with SARS-CoV-2 infection.
UNASSIGNED: Retrospective cohort study of all adults in Alberta who had a positive SARS-CoV-2 reverse transcription polymerase chain reaction test between March 1, 2020 and June 30, 2021, matched (by age, sex, Charlson Comorbidity score, and test date) with controls who had a negative reverse transcription polymerase chain reaction test.
UNASSIGNED: The 177,892 patients with laboratory confirmed SARS-CoV-2 infection (mean age 42.7 years, 49.7% female) were more likely to visit an emergency department (5.7% vs 3.3%), be hospitalized (3.4% vs 2.1%), or die (1.3% vs 0.4%) within 1 month than matched test-negative controls. After 3 months, cases were significantly more likely than controls to have an emergency department visit or hospitalization for diabetes mellitus (1.5% vs 0.7%), hypertension (0.6% vs 0.4%), heart failure (0.2% vs 0.1%), or kidney injury (0.3% vs 0.2%). In the 6,030 patients who had survived a hospitalization for COVID-19, postacute phase risks were substantially greater for diabetes mellitus (9.5% vs 3.0%, adjusted odds ratio [aOR]: 3.16 [95% CI: 2.43-4.12]), hypertension (3.5% vs 1.4%, aOR: 2.89 [95% CI: 1.97-4.23]), heart failure (2.1% vs 0.7%, aOR: 3.16 [95% CI: 1.88-5.29]), kidney injury (3.1% vs 0.8%, aOR: 2.70 [95% CI: 1.71-4.28]), bleeding (1.5% vs 0.5%, aOR: 3.40 [95% CI: 1.83-6.32]), and venous thromboembolism (0.8% vs 0.3%, aOR: 3.60 [95% CI: 1.59-8.13]).
UNASSIGNED: Clinicians should screen COVID-19 survivors for diabetes mellitus, hypertension, heart failure, and kidney dysfunction in the postacute phase.