• 文章类型: Journal Article
    建筑环境中的室内空气质量(IAQ)受到颗粒物的显著影响,挥发性有机化合物,和空气温度。最近,物联网(IoT)已经整合,以改善IAQ并保护人类健康,comfort,和生产力。这篇综述旨在强调物联网集成在监测IAQ方面的潜力。此外,本文详细介绍了研究人员在开发用于IAQ监测的物联网/移动应用程序方面的进展,以及它们对智能建筑的变革性影响,healthcare,预测性维护,和实时数据分析系统。它还概述了持续存在的挑战(例如,数据隐私,安全,和用户可接受性),阻碍了IAQ监控的有效物联网实施。最后,通过对2015年至2022年在WebofScience中索引的106种出版物的文献计量分析(BA),研究了用于IAQ监测的物联网的全球发展和研究前景。BA透露,贡献最大的国家是印度和葡萄牙,而最顶尖的生产机构和研究人员是PolitecnicodaGuarda(占TP的10.37%)和MarquesGoncalo(占TP的15.09%),分别。关键词分析揭示了四个主要研究主题:物联网,污染,监测,和健康。总的来说,本文为确定潜在的合作者提供了重要的见解,基准出版物,战略资金,以及未来IoT-IAQ研究人员的机构。
    Indoor air quality (IAQ) in the built environment is significantly influenced by particulate matter, volatile organic compounds, and air temperature. Recently, the Internet of Things (IoT) has been integrated to improve IAQ and safeguard human health, comfort, and productivity. This review seeks to highlight the potential of IoT integration for monitoring IAQ. Additionally, the paper details progress by researchers in developing IoT/mobile applications for IAQ monitoring, and their transformative impact in smart building, healthcare, predictive maintenance, and real-time data analysis systems. It also outlines the persistent challenges (e.g., data privacy, security, and user acceptability), hampering effective IoT implementation for IAQ monitoring. Lastly, the global developments and research landscape on IoT for IAQ monitoring were examined through bibliometric analysis (BA) of 106 publications indexed in Web of Science from 2015 to 2022. BA revealed the most significant contributing countries are India and Portugal, while the top productive institutions and researchers are Instituto Politecnico da Guarda (10.37% of TP) and Marques Goncalo (15.09% of TP), respectively. Keyword analysis revealed four major research themes: IoT, pollution, monitoring, and health. Overall, this paper provides significant insights for identifying prospective collaborators, benchmark publications, strategic funding, and institutions for future IoT-IAQ researchers.
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  • 文章类型: Journal Article
    背景:支持区域疫苗政策和实践的COVID-19疫苗有效性数据在非洲有限。因此,本综述旨在评估在非洲使用的COVID-19疫苗的疗效和有效性.
    方法:我们系统地检索了同行评审的随机对照试验(RCT),前瞻性和回顾性队列研究,以及报道非洲VE的病例对照研究。我们进行了偏见风险评估,这篇综述的结果被综合并以叙述的形式呈现,包括表格和数字。合成的重点是COVID-19VE对各种水平的疾病状况和结果(感染,住院治疗或危重,和死亡),时间点,和关注的变体。
    结果:共13项研究,总样本量为913,285名参与者,包括在这次审查中。大多数研究(8/13)来自南非,38.5%(5/13)是随机临床试验。研究报告说,全剂量的辉瑞-BioNTech疫苗对β(B.1.351)和Delta变体的COVID-19感染的VE为100%,对Delta变体的住院治疗的VE为96.7%。约翰逊和约翰逊疫苗的VE范围从38.1%-62.0%针对住院治疗和51.9%-86%针对β(B1.351)变体的危重疾病。Oxford-AstraZeneca疫苗对Omicron变体住院的VE为89.4%,但对B.1.351变体无效(10.4%)。Sinopharm疫苗对感染的VE为67%,对Delta变体的住院治疗的VE为46%。
    结论:在非洲使用的COVID-19疫苗可有效预防感染,住院治疗,和死亡。这些审查结果强调,所有利益攸关方需要齐心协力,加强COVID-19疫苗的获取和供应,并加强公众对接触高风险人群的认识,非洲人口中未接种疫苗的群体。
    BACKGROUND: Data on COVID-19 vaccine effectiveness to support regional vaccine policy and practice are limited in Africa. Thus, this review aimed to evaluate the efficacy and effectiveness of COVID-19 vaccines administered in Africa.
    METHODS: We systematically searched peer-reviewed randomized controlled trials (RCTs), prospective and retrospective cohort studies, and case-control studies that reported on VE in Africa. We carried out a risk of bias assessment, and the findings of this review were synthesized and presented in a narrative form, including tables and figures. The synthesis was focused on COVID-19 VE against various levels of the disease condition and outcomes (infection, hospitalization or critical, and death), time points, and variants of concern.
    RESULTS: A total of 13 studies, with a total sample size of 913,285 participants, were included in this review. The majority (8/13) of studies were from South Africa and 38.5% (5/13) were randomized clinical trials. The studies reported that a full dose of Pfizer-BioNTech vaccine had a VE of 100% against COVID-19 infection by Beta (B.1.351) and Delta variants and 96.7% against hospitalization by Delta variant. The Johnson and Johnson vaccine had VE ranging from 38.1%-62.0% against hospitalization and 51.9%- 86% against critical disease by Beta (B 1.351) variant. The Oxford-AstraZeneca vaccine had a VE of 89.4% against hospitalization by the Omicron variant but was not effective against the B.1.351 variant (10.4%). The Sinopharm vaccine had a VE of 67% against infection and 46% against hospitalization by Delta variant.
    CONCLUSIONS: COVID-19 vaccines administered in Africa were effective in preventing infections, hospitalization, and death. These review findings underscore the need for concerted efforts of all stakeholders to enhance the access and availability of COVID-19 vaccines and reinforce public awareness to reach the high-risk, unvaccinated group of the African population.
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  • 文章类型: Journal Article
    由于严重急性呼吸道综合症冠状病毒2(SARS-CoV-2)导致的2019年冠状病毒大流行严重影响了全球公共卫生安全。疫苗研究,中和抗体(NAb)和小分子抗病毒药物目前正在进行。特别是,NAb由于其明确的机制而成为有前途的治疗剂,高特异性,卓越的安全性,易于大规模生产和同时应用于预防和治疗病毒感染。许多NAb疗法已经进入临床研究阶段,显示有希望的治疗和预防效果。这些代理商已根据紧急授权程序用于预防和控制疫情。本综述总结了SARS-CoV-2相关NAb的分子靶标以及NAb开发的筛选和鉴定技术。此外,讨论了目前使用NAb仍然存在的缺点和挑战。本综述的目的是为未来任何突发传染病的NAb的发展提供参考,包括SARS-CoV-2。
    The coronavirus disease 2019 pandemic due to severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) seriously affected global public health security. Studies on vaccines, neutralizing antibodies (NAbs) and small molecule antiviral drugs are currently ongoing. In particular, NAbs have emerged as promising therapeutic agents due to their well‑defined mechanism, high specificity, superior safety profile, ease of large‑scale production and simultaneous application for both prevention and treatment of viral infection. Numerous NAb therapeutics have entered the clinical research stages, demonstrating promising therapeutic and preventive effects. These agents have been used for outbreak prevention and control under urgent authorization processes. The present review summarizes the molecular targets of SARS‑CoV‑2‑associated NAbs and screening and identification techniques for NAb development. Moreover, the current shortcomings and challenges that persist with the use of NAbs are discussed. The aim of the present review is to offer a reference for the development of NAbs for any future emergent infectious diseases, including SARS‑CoV‑2.
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  • 文章类型: Journal Article
    背景:COVID-19大流行已采取多种形式并继续演变,现在围绕着Omicron波,引起全球关注。随着COVID-19被宣布不再是国际关注的突发公共卫生事件(PHEIC),“COVID大流行还远远没有结束,自2023年1月以来,新的Omicron亚变体引起了人们的关注和关注。主要是XBB.1.5和XBB.1.16子变体,大流行仍然非常“活着”和“呼吸”。\"
    方法:这篇综述包括关于COVIDOmicron峰的当前状态的五个高度关注的问题。我们搜索了四个主要的在线数据库来回答前四个问题。最后一个,我们对文献进行了系统的回顾,带有关键字\"Omicron,\"\"指南,\"和\"建议。\"
    结果:共纳入31篇。当前Omicron波的主要症状包括典型的高烧,咳嗽,结膜炎(眼睛瘙痒),喉咙痛,流鼻涕,拥塞,疲劳,身体疼痛,和头痛。症状的中位潜伏期比以前的峰值短。针对COVID的疫苗接种仍然可以被认为对新的亚变体有效。
    结论:指南建议继续采取个人保护措施,第三和第四剂量的助推器,以及二价信使RNA疫苗增强剂的施用。一致的抗病毒治疗是使用Nirmatrelvir和Ritonavir的联合治疗,暴露前预防的共识是Tixagevimab和Cilgavimab联合使用。我们希望本文提高人们对COVID持续存在的认识,以及降低风险的方法,特别是对于高危人群。
    BACKGROUND: The COVID-19 pandemic has taken many forms and continues to evolve, now around the Omicron wave, raising concerns over the globe. With COVID-19 being declared no longer a \"public health emergency of international concern (PHEIC),\" the COVID pandemic is still far from over, as new Omicron subvariants of interest and concern have risen since January of 2023. Mainly with the XBB.1.5 and XBB.1.16 subvariants, the pandemic is still very much \"alive\" and \"breathing.\"
    METHODS: This review consists of five highly concerning questions about the current state of the COVID Omicron peak. We searched four main online databases to answer the first four questions. For the last one, we performed a systematic review of the literature, with keywords \"Omicron,\" \"Guidelines,\" and \"Recommendations.\"
    RESULTS: A total of 31 articles were included. The main symptoms of the current Omicron wave include a characteristically high fever, coughing, conjunctivitis (with itching eyes), sore throat, runny nose, congestion, fatigue, body ache, and headache. The median incubation period of the symptoms is shorter than the previous peaks. Vaccination against COVID can still be considered effective for the new subvariants.
    CONCLUSIONS: Guidelines recommend continuation of personal protective measures, third and fourth dose boosters, along with administration of bivalent messenger RNA vaccine boosters. The consensus antiviral treatment is combination therapy using Nirmatrelvir and Ritonavir, and the consensus for pre-exposure prophylaxis is Tixagevimab and Cilgavimab combination. We hope the present paper raises awareness for the continuing presence of COVID and ways to lower the risks, especially for at-risk groups.
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  • 文章类型: Journal Article
    目标:COVID-19和黑人社区不成比例的治安最近引起了公众对反黑人种族主义(ABR)弥漫健康的社会意识,社会,和文化机构。然而,在不断变化的大流行背景下,关于应对ABR的公共卫生措施的实施知之甚少。本次范围审查的目的是提供2019年12月至2022年6月期间为解决北美司法管辖区ABR而采取的公共卫生举措的概述。
    方法:2021年6月在MEDLINE进行了公共卫生倡议的搜索,OvidEmbase,EBSCost,CINAHL,Socindex,和Google。CA.包括那些侧重于布莱克的倡议,非洲侨民,或北美背景下的非裔美国人社区。社区主导的行动,以及初级卫生保健方面的举措,学术期刊,那些广泛关注种族化社区的人,被排除在这篇评论之外。
    结果:这篇综述包括75篇文章,这表明ABR成为公共卫生的优先事项。解决结构性ABR的战略和行动计划是观察到的最常见的举措类型(n=21),其次是项目或干预措施(n=16),预算拨款或投资(n=8),工作队(n=7),组织能力指导和建议(n=8),以行动为导向的ABR声明为公共卫生危机(n=8),以及立法和授权(n=7)。倡议主要是两个或两个以上社会经济主题的交叉(n=23),而组织变革也很常见(n=16)。当前文献中的差距包括缺乏社区参与和对已确定的行动的结果衡量,这限制了对利益社区的机构问责。
    结论:这项研究为公共卫生对社会正义的问责提供了见解。这项研究概述了上游干预措施的活动,组织变革,以及塑造反种族主义变革的资源分配,并要求那些计划旨在服务的人进行评估和投入。
    OBJECTIVE: The syndemic that is COVID-19 and the disproportionate policing of Black communities have recently generated mass social consciousness of the anti-Black racism (ABR) pervading health, social, and cultural institutions. However, little is known about the implementation of public health measures addressing ABR in an evolving pandemic context. The objective of this scoping review is to provide an overview of public health initiatives undertaken to address ABR across North American jurisdictions between December 2019 and June 2022.
    METHODS: A search for public health initiatives was conducted in June 2021 across MEDLINE, Ovid Embase, EBSChost, CINAHL, SocINDEX, and Google.ca. Included initiatives were those focussing on Black, African diasporic, or African American communities in the North American context. Community-led action, as well as initiatives in primary healthcare care, academic journals, and those broadly focused on racialized communities, were excluded from this review.
    RESULTS: Seventy-five articles were included in this review, suggesting that ABR emerged as a public health priority. Strategies and action plans to address structural ABR were the most common types of initiatives observed (n = 21), followed by programs or interventions (n = 16), budget allocations or investments (n = 8), task forces (n = 7), guidance and recommendations for organizational capacity (n = 8), action-oriented declarations of ABR as a public health crisis (n = 8), and legislation and mandates (n = 7). Initiatives were largely cross-cutting of two or more socioeconomic themes (n = 23), while organizational change was also common (n = 16). Gaps in the current literature include a lack of community participation and outcome measurement for actions identified, which limit institutional accountability to communities of interest.
    CONCLUSIONS: This research provides insights on public health accountability to social justice. This research outlines activities in upstream interventions, organizational transformation, and resource allocation in shaping anti-racist change, and require evaluation and input from those whom initiatives are intended to serve.
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  • 文章类型: Journal Article
    目标:在他们职业生涯的某个阶段,许多医护人员会经历与无法采取道德或道德上正确的行动有关的心理困扰,因为它符合他们自己的价值观;一种被称为道德困扰的现象。同样,有越来越多的报告说,医护人员经历了长期的精神和心理痛苦,除了内部不和谐,被称为道德伤害。这篇综述研究了在一系列临床环境中使用的健康和社会护理人员(HSCW)中与道德困扰和伤害相关的触发因素和因素,目的是了解如何减轻道德困扰的影响并确定潜在的预防性干预措施。
    方法:根据Cochrane和系统评价和荟萃分析指南的首选报告项目的建议进行系统评价和报告。在2024年1月之前,对2个主要数据库进行了定期搜索和更新(CENTRAL,PubMed)和三个专业数据库(Scopus,CINAHL,PsycArticles),同时手工搜索研究登记数据库和其他系统评价参考列表。符合条件的研究包括HSCW样本,探索道德困扰/伤害作为主要目标,用英语或意大利语写的.逐字引用被提取,文章质量通过CASP工具包进行评估。进行了主题分析,以确定模式并将代码安排到主题中。探讨了文化和多样性等具体因素,以及大流行等特殊情况的影响。
    结果:49项研究的51份报告被纳入综述。原因和触发因素分为三个领域:个人,社会,和组织。在个人层面,患者的护理选择,专业人士的信仰,控制源,任务规划,以及根据经验做出决定的能力,被指示为可能导致或引发道德困扰的元素。此外,与CoVID-19大流行有关,使用/访问个人保护资源。社会或关系因素与倡导和与患者及家属沟通的责任有关,和专业人员自己的支持网络。在组织层面,层次结构,法规,支持,工作量,文化,和资源(人员和设备)被确定为可能影响专业人员道德舒适度的要素。病人护理,道德/信仰/标准,宣传作用和背景文化是最有参考意义的要素。关于文化差异和多样性的数据不足以做出假设。缺乏资源和迅速的政策变化已成为与大流行有关的关键触发因素。这表明,那些负责政策决定的人应该注意突然和自上而下的变化对工作人员的潜在影响。
    结论:这篇综述表明,道德伤害的原因和触发因素是多因素的,并且在很大程度上受专业人员工作的背景和制约因素的影响。道德困扰与照顾的义务和责任有关,和专业人员优先考虑患者的健康。如果组织的价值观和规章制度与个人的信仰相反,对专业人士的健康和保留的影响是可以预期的。减轻道德困扰的组织策略,或长期的道德伤害后遗症,应该针对个人,社会,以及本次审查中确定的组织要素。
    OBJECTIVE: At some point in their career, many healthcare workers will experience psychological distress associated with being unable to take morally or ethically correct action, as it aligns with their own values; a phenomenon known as moral distress. Similarly, there are increasing reports of healthcare workers experiencing long-term mental and psychological pain, alongside internal dissonance, known as moral injury. This review examined the triggers and factors associated with moral distress and injury in Health and Social Care Workers (HSCW) employed across a range of clinical settings with the aim of understanding how to mitigate the effects of moral distress and identify potential preventative interventions.
    METHODS: A systematic review was conducted and reported according to recommendations from Cochrane and Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Searches were conducted and updated regularly until January 2024 on 2 main databases (CENTRAL, PubMed) and three specialist databases (Scopus, CINAHL, PsycArticles), alongside hand searches of study registration databases and other systematic reviews reference lists. Eligible studies included a HSCW sample, explored moral distress/injury as a main aim, and were written in English or Italian. Verbatim quotes were extracted, and article quality was assessed via the CASP toolkit. Thematic analysis was conducted to identify patterns and arrange codes into themes. Specific factors like culture and diversity were explored, and the effects of exceptional circumstances like the pandemic.
    RESULTS: Fifty-one reports of 49 studies were included in the review. Causes and triggers were categorised under three domains: individual, social, and organisational. At the individual level, patients\' care options, professionals\' beliefs, locus of control, task planning, and the ability to make decisions based on experience, were indicated as elements that can cause or trigger moral distress. In addition, and relevant to the CoVID-19 pandemic, was use/access to personal protection resources. The social or relational factors were linked to the responsibility for advocating for and communication with patients and families, and professionals own support network. At organisational levels, hierarchy, regulations, support, workload, culture, and resources (staff and equipment) were identified as elements that can affect professionals\' moral comfort. Patients\' care, morals/beliefs/standards, advocacy role and culture of context were the most referenced elements. Data on cultural differences and diversity were not sufficient to make assumptions. Lack of resources and rapid policy changes have emerged as key triggers related to the pandemic. This suggests that those responsible for policy decisions should be mindful of the potential impact on staff of sudden and top-down change.
    CONCLUSIONS: This review indicates that causes and triggers of moral injury are multifactorial and largely influenced by the context and constraints within which professionals work. Moral distress is linked to the duty and responsibility of care, and professionals\' disposition to prioritise the wellbeing of patients. If the organisational values and regulations are in contrast with individuals\' beliefs, repercussions on professionals\' wellbeing and retention are to be expected. Organisational strategies to mitigate against moral distress, or the longer-term sequalae of moral injury, should address the individual, social, and organisational elements identified in this review.
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  • 文章类型: Journal Article
    背景:在COVID-19大流行期间,世界各地的政府和公共卫生机构在互联网上遇到了社交媒体介导的信息流行病的困难。现有的公共卫生危机沟通策略需要更新。然而,在COVID-19大流行期间,世界各国政府和公共卫生机构的危机沟通经验尚未得到系统地汇编,需要更新的危机沟通策略。
    目的:本系统综述旨在收集和组织发件人的危机沟通经验(即,政府和公共卫生机构)在COVID-19大流行期间。我们的重点是探索政府和公共卫生机构经历的困难,在COVID-19大流行期间,政府和公共卫生机构在危机传播中的最佳做法,以及在未来公共卫生危机中应该克服的挑战。
    方法:我们计划于2024年5月1日开始文献检索。我们将搜索PubMed,MEDLINE,CINAHL,PsycINFO,心术,通讯摘要,和WebofScience。我们将过滤我们的数据库搜索从2020年及以后的搜索。我们将通过引用SPIDER(示例,兴趣现象,设计,评价,和研究类型)工具来搜索数据库中的摘要。我们打算包括政府和公共卫生机构对危机沟通的定性研究(例如,官员,工作人员,卫生专业人员,和研究人员)对公众。基于数据的定量研究将被排除在外。只有用英语写的论文将被包括在内。有关研究特征的数据,研究目的,参与者特征,方法论,理论框架,危机沟通的对象,并提取关键结果。将使用JoannaBriggs研究所关键评估清单对合格研究的方法学质量进行评估,以进行定性研究。共有两名独立审稿人将共同负责筛选出版物,数据提取,和质量评估。分歧将通过讨论解决,将咨询第三位审稿人,如有必要。调查结果将在表格和概念图中进行总结,并在描述性和叙述性审查中进行综合。
    结果:将以与我们的研究目标和兴趣相对应的方式系统地整合和呈现结果。我们预计此次审查的结果将于2024年底提交发布。
    结论:据我们所知,这将是对政府和公共卫生机构在COVID-19大流行期间向公众传达危机的经验的首次系统回顾。这项审查将有助于将来改进政府和公共卫生机构向公众传达危机的指南。
    背景:PROSPEROCRD42024528975;https://tinyurl.com/4fjmd8te。
    PRR1-10.2196/58040。
    BACKGROUND: Governments and public health agencies worldwide experienced difficulties with social media-mediated infodemics on the internet during the COVID-19 pandemic. Existing public health crisis communication strategies need to be updated. However, crisis communication experiences of governments and public health agencies worldwide during the COVID-19 pandemic have not been systematically compiled, necessitating updated crisis communication strategies.
    OBJECTIVE: This systematic review aims to collect and organize the crisis communication experiences of senders (ie, governments and public health agencies) during the COVID-19 pandemic. Our focus is on exploring the difficulties that governments and public health agencies experienced, best practices in crisis communication by governments and public health agencies during the COVID-19 pandemic in times of infodemic, and challenges that should be overcome in future public health crises.
    METHODS: We plan to begin the literature search on May 1, 2024. We will search PubMed, MEDLINE, CINAHL, PsycINFO, PsycARTICLES, Communication Abstracts, and Web of Science. We will filter our database searches to search from the year 2020 and beyond. We will use a combination of keywords by referring to the SPIDER (Sample, Phenomenon of Interest, Design, Evaluation, and Research type) tool to search the abstracts in databases. We intend to include qualitative studies on crisis communication by governments and public health agencies (eg, officials, staff, health professionals, and researchers) to the public. Quantitative data-based studies will be excluded. Only papers written in English will be included. Data on study characteristics, study aim, participant characteristics, methodology, theoretical framework, object of crisis communication, and key results will be extracted. The methodological quality of eligible studies will be assessed using the Joanna Briggs Institute critical appraisal checklist for qualitative research. A total of 2 independent reviewers will share responsibility for screening publications, data extraction, and quality assessment. Disagreement will be resolved through discussion, and the third reviewer will be consulted, if necessary. The findings will be summarized in a table and a conceptual diagram and synthesized in a descriptive and narrative review.
    RESULTS: The results will be systematically integrated and presented in a way that corresponds to our research objectives and interests. We expect the results of this review to be submitted for publication by the end of 2024.
    CONCLUSIONS: To our knowledge, this will be the first systematic review of the experiences of governments and public health agencies regarding their crisis communication to the public during the COVID-19 pandemic. This review will contribute to the future improvement of the guidelines for crisis communication by governments and public health agencies to the public.
    BACKGROUND: PROSPERO CRD42024528975; https://tinyurl.com/4fjmd8te.
    UNASSIGNED: PRR1-10.2196/58040.
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  • 文章类型: Journal Article
    The COVID-19 epidemic has made significant changes in the organization of treatment process both at the inpatient and outpatient stages.
    OBJECTIVE: To analyze the work results of the rehabilitation units dealing with patients who have suffered from COVID-19, in order to summarize the used approaches to medical rehabilitation and improve the effectiveness of care delivery in the recovery phase.
    CONCLUSIONS: Currently, the rehabilitation system has been effectively rebuilt to meet new challenges of the COVID-19 pandemic. Recovery of patients with pronounced neurotic disorders has become a showing good results direction in rehabilitation. It is necessary to implement a tight integration of physical exercises and telerehabilitation facilities in order to effectively settle the main issues directly related to the treatment and recovery of patients with COVID-19 and other pathologies. The control, prevention, treatment and rehabilitation of other infectious diseases will have great prospects regarding the possibility of remote follow-up of patients and correction of their functional state of the body in the nearest future.
    Эпидемия COVID-19 внесла существенные коррективы в организацию лечебного процесса как на стационарном, так и на амбулаторном этапах.
    UNASSIGNED: Провести анализ результатов работы реабилитационных подразделений, занимающихся пациентами, перенесшими COVID-19, с целью обобщения применяемых подходов к медицинской реабилитации и повышения эффективности оказания помощи на этапе восстановления.
    UNASSIGNED: В настоящее время система реабилитации эффективно перестроилась под новые вызовы пандемии COVID-19. Направлением в реабилитации, демонстрирующим хорошие результаты, стало восстановление пациентов с выраженными невротическими расстройствами. Для эффективного решения основных вопросов, непосредственно связанных с лечением и восстановлением пациентов с COVID-19 и другими патологиями, необходимо осуществить плотную интеграцию физических упражнений и средств телереабилитации. В ближайшем будущем контроль, профилактика, лечение и реабилитация других инфекционных заболеваний будут иметь большие перспективы в отношении возможности дистанционного динамического наблюдения за пациентами и коррекции их функционального состояния организма.
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  • 文章类型: Journal Article
    陆地公共交通是城市内部和城市之间的重要纽带,如何控制COVID-19在陆地公共交通中的传播是我们日常生活中的一个关键问题。然而,关于SARS-CoV-2在陆地公共交通中的传播仍然存在许多不一致的观点和看法,这限制了我们实施有效干预措施的能力。这篇综述的目的是概述有关该流行病在陆地公共交通中的传播特征和途径的文献,以及调查影响其传播的因素,并提供可行的措施来减轻乘客的感染风险。我们通过搜索科学网获得了898篇论文,Pubmed,和世卫组织全球COVID数据库的关键词,并最终选择了45篇论文,可以解决本评论的目的。由于拥挤等特点,陆路公共交通是COVID-19的高发地区,通风不足,暴露时间长,和环境封闭。与表面接触透射和液滴喷雾透射不同,气溶胶吸入传播不仅可以在短距离内发生,而且可以在长距离内发生。通风不足是影响气溶胶远距离传播的最重要因素。其他传播因素(例如,人际距离,相对取向,和环境条件)也应注意,本文对此进行了总结。为了解决各种影响因素,必须提出切实可行的预防措施。其中,增加通风,特别是新鲜空气(即,自然通风),已证明可有效降低室内感染风险。许多预防措施也是有效的,比如扩大社交距离,避免面对面的定向,设置物理分区,消毒,避免说话,等等。随着对该流行病的研究的加强,人们已经打破了许多感知的障碍,但仍需要对陆地公共交通的监测系统和预防措施进行更全面的研究。
    Land public transport is an important link within and between cities, and how to control the transmission of COVID-19 in land public transport is a critical issue in our daily lives. However, there are still many inconsistent opinions and views about the spread of SARS-CoV-2 in land public transport, which limits our ability to implement effective interventions. The purpose of this review is to overview the literature on transmission characteristics and routes of the epidemic in land public transport, as well as to investigate factors affecting its spread and provide feasible measures to mitigate the infection risk of passengers. We obtained 898 papers by searching the Web of Science, Pubmed, and WHO global COVID database by keywords, and finally selected 45 papers that can address the purpose of this review. Land public transport is a high outbreak area for COVID-19 due to characteristics like crowding, inadequate ventilation, long exposure time, and environmental closure. Different from surface touch transmission and drop spray transmission, aerosol inhalation transmission can occur not only in short distances but also in long distances. Insufficient ventilation is the most important factor influencing long-distance aerosol transmission. Other transmission factors (e.g., interpersonal distance, relative orientation, and ambient conditions) should be noticed as well, which have been summarized in this paper. To address various influencing factors, it is essential to suggest practical and efficient preventive measures. Among these, increased ventilation, particularly the fresh air (i.e., natural ventilation), has proven to effectively reduce indoor infection risk. Many preventive measures are also effective, such as enlarging social distance, avoiding face-to-face orientation, setting up physical partitions, disinfection, avoiding talking, and so on. As research on the epidemic has intensified, people have broken down many perceived barriers, but more comprehensive studies on monitoring systems and prevention measures in land public transport are still needed.
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  • 文章类型: Journal Article
    糖尿病患者感染COVID-19的风险增加,症状往往更严重。本系统评价探讨了影响糖尿病患者COVID-19高感染率的潜在机制。它回顾了关于病毒和糖尿病途径之间相互作用的新证据,特别是糖尿病生理学如何有助于更高的病毒接受,病毒进入和致病性,以及疾病症状的严重程度。最后,它审查了我们在研究这些机制时面临的挑战,并提供了可能有助于我们对抗当前和未来大流行的新战略。
    Diabetics have an increased risk of contracting COVID-19 infection and tend to have more severe symptoms. This systematic review explores the potential mechanisms influencing the high prevalence of COVID-19 infections in individuals with diabetes. It reviews the emerging evidence about the interactions between viral and diabetic pathways, particularly how diabetes physiology could contribute to higher viral reception, viral entry and pathogenicity, and the severity of disease symptoms. Finally, it examines the challenges we face in studying these mechanisms and offers new strategies that might assist our fight against current and future pandemics.
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