背景:龋齿是一个动态过程。通过使用治疗剂,早期,非空化病变和龋齿仅限于釉质可以停止甚至再矿化。对于初始龋齿病变的再矿化,研究了许多非氟化再矿化剂。
目的:一项观察性研究,以评估磷酸三钙(TCP)的再矿化功效,纳米羟基磷灰石(nHAp)和臭氧再矿化剂对人工龋齿的影响。
方法:在这项观察性研究中,人工龋齿是在40颗前磨牙上产生的。稍后,再矿化剂(A组:nHAp,B组:TCP,C组:臭氧再矿化剂,D组:对照组(去离子水)用于再矿化脱矿质牙齿。利用维氏硬度数,评估了脱矿质和再矿化水平.随后,使用Tukey的HSD(诚实的显着差异)和SPSS版本21.0中的ANOVA测试对这些读数进行了统计评估。P值设定为0.05以下。
结果:脱矿质后,牙釉质显微硬度值下降,A组32%,B组26%,C组22%,D组21%,分别。从基线到脱矿质,所有组的显微硬度均有统计学显著下降.再矿化后,A组,B,C的显微硬度增加,而D组没有变化。这表明A组的再矿化率最高,其次是B组和C组。
结论:nHAp和TCP具有更大的再矿化能力,可用于处理最初的龋齿病变。
BACKGROUND: Dental caries is a dynamic process. By using therapeutic agents, early, noncavitated lesions and caries limited to the enamel can be stopped or even remineralized. For the remineralization of the initial carious lesion, many nonfluoridated remineralizing agents were investigated.
OBJECTIVE: An observational study to assess the remineralizing efficacy of tricalcium phosphate (TCP), nano-hydroxyapatite (nHAp) and ozone remineralizing agents on the artificial carious lesion.
METHODS: In this observational research, the artificial carious lesion was produced on extracted 40 premolar teeth. Later, remineralizing agents (Group A: nHAp, Group B: TCP, Group C: Ozone remineralizing agents, Group D: Control group (Deionized water) were used to remineralize demineralized teeth. Utilizing the Vickers Hardness Number, the level of demineralization and remineralization was assessed. Later these readings were statistically assessed using the Tukey\'s HSD (honestly significant difference) and ANOVA tests in SPSS version 21.0. The P value was set at 0.05 or less.
RESULTS: After demineralization, there was a decrease in enamel microhardness values, with 32% in Group A, 26% in Group B, 22% in Group C, and 21% in Group D, respectively. From the baseline to demineralization, there was a statistically significant decrease in microhardness across all groups. After remineralization, Groups A, B, and C experienced an increase in microhardness while Group D experienced no changes. This showed that Group A had the highest remineralization percentage, followed by Group B and Group C.
CONCLUSIONS: nHAp and TCP had the greater remineralizing ability, which can be used to manage initial carious lesions.