兔子由于其有效的生长和生产力而对商业肉类生产至关重要,品种像新西兰白(NZW),加利福尼亚(CAL),和Gabali(GAB)兔子在凋落物中具有独特的遗传性状,增长,和car体特征。本研究旨在评估遗传力(H2),产仔数的遗传和表型相关性(rg和rp),加利福尼亚州(CAL)的体重和car体特征,新西兰白兔(NZW)和Gabali(GA)。随着TBC1D1、NPY基因表达谱的探索,AGRP,POMC,瘦素,GH,GHR,IGF-1,CAA,GPR,ACC,CPT1、FAS、和大脑中的CART,肝脏,和不同品种兔的肉组织。品种基因型对产仔数(LS)有显著影响,产仔数(LW),12周时的体重(BW12),和每日体重增加(DWG)特征。NZW兔在产仔数和产仔数方面表现优异,而CAL兔记录的BW12和DWG值最高。产仔数的遗传力估计值(h2)通常较低(范围为0.05至0.12),体重中等(范围为0.16至0.31)。产仔数的遗传(rg)和表型(rp)相关性均为阳性和中等(范围为0.08至0.48),而体重的相关性范围为0.21至0.58。此外,与NZW和GA兔相比,CAL兔表现出更高的car体性状。就品种特异性基因表达模式而言,新西兰白兔(NZW)表现出与能量代谢相关的关键基因(TBC1D1)的最高表达水平,食欲调节(NPY,AGRP,POMC),养分运输(CAA),以及脑和肝组织中的G蛋白偶联受体(GPR)。加利福尼亚(CAL)兔在脑组织和GH中表现出ACC基因的优越基因表达,GHR,以及大脑和肉类组织中的IGF-1基因。Gabali(GAB)兔表现出最高的TBC1D1、NPY表达水平,AGRP,GPR,和肉组织中的ACC基因。这些品种特异性基因表达差异,结合基因评估工作,有可能提高兔子的繁殖和生产性能,为兔子育种计划和遗传选择提供有价值的见解。
Rabbits are essential for commercial meat production due to their efficient growth and productivity, breeds like New Zealand
White (NZW), Californian (CAL), and Gabali (GAB) rabbits offer unique genetic traits in litter, growth, and carcass traits. This study aimed to evaluate heritability (h2), genetic and phenotypic correlations (rg and rp) for litter size, body weight and carcass traits across California (CAL), New Zealand
white (NZW) and Gabali (GA) rabbits. Along with exploring gene expression profiles of TBC1D1, NPY, AGRP, POMC, Leptin, GH, GHR, IGF-1, CAA, GPR, ACC, CPT1, FAS, and CART in the brain, liver, and meat tissues of different rabbit breeds. The breed genotype had a significant impact on litter size (LS), litter weight (LW), body weight at 12 weeks (BW12), and daily weight gain (DWG) traits. NZW rabbits displayed superior performance in terms of litter size and litter weight, while CAL rabbits recorded the highest values for BW12 and DWG. Heritability estimates (h2) were generally low for litter size (ranging from 0.05 to 0.12) and medium for body weight (ranging from 0.16 to 0.31). Both genetic (rg) and phenotypic (rp) correlations for litter size were positive and moderate (ranging from 0.08 to 0.48), while correlations for body weight ranged from 0.21 to 0.58. Additionally, CAL rabbits exhibited higher carcass traits compared to NZW and GA rabbits. In terms of breed-specific gene expression patterns, New Zealand
White (NZW) rabbits displayed the highest expression levels of key genes related to energy metabolism (TBC1D1), appetite regulation (NPY, AGRP, POMC), nutrient transport (CAA), and G protein-coupled receptors (GPR) in both brain and liver tissues. Californian (CAL) rabbits exhibited superior gene expression of the ACC gene in brain tissue and GH, GHR, and IGF-1 genes in brain and meat tissues. Gabali (GAB) rabbits demonstrated the highest expression levels of TBC1D1, NPY, AGRP, GPR, and ACC genes in meat tissues. These breed-specific gene expression differences, combined with genetic evaluation efforts, have the potential to enhance reproductive and productive performance in rabbits, offering valuable insights for rabbit breeding programs and genetic selection.