■妊娠期糖尿病(DIP)与不良胎儿和母体结局相关。DIP被分类为预先存在或新发病的糖尿病(DM),分为妊娠期DM(GDM)和新检测的2型(N-T2D)。在卡塔尔,所有已知没有预先存在DM的孕妇在第一次产前护理访问期间和妊娠24周后接受DIP筛查。该研究旨在报告DIP筛查率,DIP的患病率,以及普遍筛查计划对不良妊娠结局的影响。
■这项回顾性研究包括2019年至2022年在哈马德医疗公司(HMC)医院分娩的所有妇女。新发DIP使用WHO-2013标准定义。主要结果是卡塔尔的筛查率和DIP患病率。次要结局是早产的差异,C-section,巨大儿,胎龄大(LGA),小于胎龄(SGA),和子宫内胎儿死亡(IUFD)之间有或没有GDM的妇女。
■我们包括94,422名妇女,他们在全国112,080名新生儿中分娩了96,017名新生儿(85.7%)。先前患有糖尿病的妇女人数为2496名妇女。在91926名合格妇女中,筛选了77,372(84.2%)的DIP。GDM的患病率为31.6%(95%CI:31.3-32.0%);N-T2D为2.2%(95%CI:2.1-2.3%),并且预先存在的2型DM和1型DM分别为2.6%(95%CI:0.8-3.0%)和0.2%(0.19-0.25),分别。与非GDM组相比,GDM患者年龄较大(30.8±5.3岁和29.7±5.2岁,p<0.001)。在调整了年龄之后,GDM患者的IUFD和SGA风险较低(0.63[95%CI0.50-0.80,p<0.001],分别为0.88[95%CI0.84-0.92,p<0.001]),但发生剖腹产和LFD的风险较高(1.07[95%CI1.04-1.10,p<0.001],1.09[95%CI1.01-1.15,p=0.01],分别,与无GDM的女性相比。
■在符合筛查资格的女性中,84.2%的人被卡塔尔的DIP计划筛查。卡塔尔的DIP患病率为36.9%。综合护理对于妊娠期糖尿病的筛查和管理至关重要。
■作者没有收到此项目的任何资助。
UNASSIGNED: Diabetes in pregnancy (DIP) is associated with adverse fetal and maternal outcomes. DIP is classified as either pre-existing or new-onset diabetes mellitus (DM), which is classified into gestational DM (GDM) and newly detected type 2 (N-T2D). All pregnant women in Qatar who are not known to have pre-existing DM are offered screening for DIP during the first antenatal care visit and after 24 weeks gestation. The study aims to report the DIP screening rates, the prevalence of DIP, and the impact of the universal screening program on adverse pregnancy outcomes.
UNASSIGNED: This retrospective study included all women who gave birth in Hamad Medical Corporation (HMC) hospitals between 2019 and 2022. New-onset DIP was defined using the WHO-2013 criteria. The primary outcomes were the screening rates and the prevalence of DIP in Qatar. The secondary outcomes were the difference in preterm delivery, C-section, macrosomia, large for gestational age (LGA), small for gestational age (SGA), and intra-uterine fetal death (IUFD) between women with or without GDM.
UNASSIGNED: We included 94,422 women who gave birth to 96,017 neonates (85.7%) out of 112,080 neonates born nationwide. The number of women with pre-existing diabetes was 2496 women. Of 91,926 eligible women, 77,372 (84.2%) were screened for DIP. The prevalence of GDM is 31.6% (95% CI: 31.3-32.0%); N-T2D is 2.2% (95% CI: 2.1-2.3%), and pre-existing Type 2 DM and Type 1 DM was 2.6% (95% CI: 0.8-3.0%) and 0.2% (0.19-0.25), respectively. Compared to the non-GDM group, women with GDM were older (30.8 ± 5.3 versus 29.7 ± 5.2 years, p < 0.001). After adjusting for age, women with GDM had lower risk of IUFD and SGA (0.63 [95% CI 0.50-0.80, p < 0.001], 0.88 [95% CI 0.84-0.92, p < 0.001] respectively) but higher risk of C-section and LFD (1.07 [95% CI 1.04-1.10, p < 0.001], 1.09 [95% CI 1.01-1.15, p = 0.01], respectively, compared to women with no-GDM.
UNASSIGNED: Of the women eligible for screening, 84.2% were screened by the DIP program in Qatar. The prevalence of DIP in Qatar is 36.9%. Integrated care is critical for the screening and management of diabetes during pregnancy.
UNASSIGNED: The authors did not receive any funding for this project.