■房间隔封堵器侵蚀的风险,特别是Amplatzer中隔封堵器,已被描述为在短主动脉边缘的患者中更高。卵圆孔未闭(PFO)闭合装置也有类似的担忧,但只有罕见的侵蚀案例。当这不一定是问题时,可能由于担心PFO患者中的装置侵蚀而选择较小的装置。
■作者旨在评估使用AmplatzerPFO装置在短(<9mm)主动脉边缘患者中关闭PFO后的结果。
■我们对任何适应症的PFO闭合进行了回顾性分析,2006年至2017年之间在第四纪中心。术前重新测量经食管超声心动图参数,包括主动脉边缘。通过与省级行政数据库的链接获得了长期结果。
■在研究期间,324例患者使用AmplatzerPFO装置进行PFO封堵,平均年龄49.8岁;61%的患者主动脉边缘短(<9mm)。最常见的指征是隐源性卒中(72%);主动脉距离较长的患者更有可能出现非卒中的闭合指征。糖尿病(15%对6.5%,P=0.04),和心力衰竭(15.7%vs4%,P<0.001)。在平均7年的随访中,没有需要心脏手术的器械侵蚀或栓塞病例.
■在长期行政随访的大型队列中(1,394患者-年),即使在主动脉边缘较短的患者中,也可以安全地植入AmplatzerPFO装置.
UNASSIGNED: The risk of erosion of an atrial septal closure device, in particular the Amplatzer Septal Occluder, has been described as higher in patients with a short aortic rim. Similar concern has been applied to patent foramen ovale (PFO) closure devices, but there are only rare reported cases of erosion. It may be that smaller devices are chosen due to fear of device erosion in PFO patients when this is not necessarily an issue.
UNASSIGNED: The authors aimed to assess outcomes after PFO closure with the Amplatzer PFO device in patients with a short (<9 mm) aortic rim.
UNASSIGNED: We performed a retrospective analysis of PFO closure for any indication, between 2006 and 2017 at a quaternary center. Preprocedural transesophageal echocardiographic parameters including the aortic rim were remeasured. Long-term outcomes were obtained by linkage to provincial administrative databases.
UNASSIGNED: Over the study period, 324 patients underwent PFO closure with the Amplatzer PFO device, with a mean age of 49.8 years; 61% had a short aortic rim (<9 mm). The most common indication was cryptogenic stroke (72%); those with longer aortic distance were more likely to have a non-stroke indication for closure, diabetes (15% vs 6.5%, P = 0.04), and heart failure (15.7% vs 4%, P < 0.001). Over a median 7 years of follow-up, there were no cases of device erosion or embolization requiring cardiac surgery.
UNASSIGNED: In a large cohort with long-term administrative follow-up (1,394 patient-years), implantation of an Amplatzer PFO device was performed safely even in patients with a short aortic rim.