UNASSIGNED: The authors aimed to assess outcomes after PFO closure with the Amplatzer PFO device in patients with a short (<9 mm) aortic rim.
UNASSIGNED: We performed a retrospective analysis of PFO closure for any indication, between 2006 and 2017 at a quaternary center. Preprocedural transesophageal echocardiographic parameters including the aortic rim were remeasured. Long-term outcomes were obtained by linkage to provincial administrative databases.
UNASSIGNED: Over the study period, 324 patients underwent PFO closure with the Amplatzer PFO device, with a mean age of 49.8 years; 61% had a short aortic rim (<9 mm). The most common indication was cryptogenic stroke (72%); those with longer aortic distance were more likely to have a non-stroke indication for closure, diabetes (15% vs 6.5%, P = 0.04), and heart failure (15.7% vs 4%, P < 0.001). Over a median 7 years of follow-up, there were no cases of device erosion or embolization requiring cardiac surgery.
UNASSIGNED: In a large cohort with long-term administrative follow-up (1,394 patient-years), implantation of an Amplatzer PFO device was performed safely even in patients with a short aortic rim.
■作者旨在评估使用AmplatzerPFO装置在短(<9mm)主动脉边缘患者中关闭PFO后的结果。
■我们对任何适应症的PFO闭合进行了回顾性分析,2006年至2017年之间在第四纪中心。术前重新测量经食管超声心动图参数,包括主动脉边缘。通过与省级行政数据库的链接获得了长期结果。
■在研究期间,324例患者使用AmplatzerPFO装置进行PFO封堵,平均年龄49.8岁;61%的患者主动脉边缘短(<9mm)。最常见的指征是隐源性卒中(72%);主动脉距离较长的患者更有可能出现非卒中的闭合指征。糖尿病(15%对6.5%,P=0.04),和心力衰竭(15.7%vs4%,P<0.001)。在平均7年的随访中,没有需要心脏手术的器械侵蚀或栓塞病例.
■在长期行政随访的大型队列中(1,394患者-年),即使在主动脉边缘较短的患者中,也可以安全地植入AmplatzerPFO装置.