目的:本研究旨在探讨使用CorvisST测量生物力学参数来预测小梁切除术或丝裂霉素C(MMC)的气泡针刺翻修后低张力黄斑病变和脉络膜脱离(CD)的发生的有效性。
■临床队列研究方法:本研究包括100例接受了MMC小梁切除术(88例患者的88眼)或大泡针刺(12例患者的12眼)的患者的100眼。从1)手术(小梁切除术或大泡针刺)中确定了低眼压并发症的重要预测指标,2)年龄,3)性别,4)疾病类型(原发性开角型青光眼[POAG],剥脱性青光眼[EG]或其他),5)镜头状态(phakia或伪眼镜),6)术前Goldmann压平眼压(GAT),眼压(IOP),7)术前中央角膜厚度(CCT),8)术前眼轴长度(AL),9)术前前房(AC)深度,10)“最小眼压”(低眼压并发症发生时的眼压值,否则小梁切除术或大泡针刺3个月内的最低眼压),11)术前角膜曲率,和12-24)12使用多元逻辑回归的CorvisST参数。
结果:有13和21只眼出现低眼压性黄斑病变和CD,分别。男性,术前GAT眼压升高和HC偏转幅度升高是低眼压性黄斑病变发生的显著预测因素(p<0.05).另一方面,较短的轴向长度,更薄的CCT,术前较高的GAT眼压和假晶状体眼是CD发生的显著预测因子(p<0.05)。
结论:尽管术前GAT眼压较高,但男性和HC偏转幅度较大的低眼压性黄斑病变的发生应特别注意。确定了不同的危险因素;较短的轴向长度,更薄的CCT,术前GAT眼压和假晶状体眼较大。
OBJECTIVE: This study aimed to investigate the usefulness of measuring biomechanical parameters using the Corvis ST to predict the occurrence of hypotony maculopathy and choroidal detachment (CD) following
trabeculectomy or bleb needling revision with mitomycin C (MMC).
UNASSIGNED: Clinical cohort study METHODS: This study included 100 eyes of 100 patients who underwent
trabeculectomy (88 eyes of 88 patients) or bleb needling (12 eyes of 12 patients) with MMC. A significant predictor of hypotony complications was identified from 1) operation (
trabeculectomy or bleb needling), 2) age, 3) sex, 4) disease type (primary open angle glaucoma [POAG], exfoliation glaucoma [EG] or other), 5) lens status (phakia or pseudophakia), 6) preoperative Goldmann applanation tonometry (GAT) intraocular pressure (IOP), 7) preoperative central corneal thickness (CCT), 8) preoperative axial length (AL), 9) preoperative anterior chamber (AC) depth, 10) \"Min IOP\" (IOP value when hypotony complications occurred, otherwise the minimum IOP during 3 months from
trabeculectomy or bleb needling), 11) preoperative corneal curvature, and 12- 24) 12 Corvis ST parameters using multivariate logistic regression.
RESULTS: There were 13 and 21 eyes developed hypotony maculopathy and CD, respectively. Male gender, greater preoperative GAT IOP and greater HC deflection Amplitude were significant predictors of the occurrence of hypotony maculopathy (p <0.05). On the other hand, shorter axial length, thinner CCT, greater preoperative GAT IOP and pseudophakia were significant predictors of the occurrence of CD (p <0.05).
CONCLUSIONS: A careful attention should be paid to the occurrence of hypotony maculopathy with male gender and greater HC deflection Amplitude despite higher preoperative GAT IOP. Different risk factors were identified; shorter axial length, thinner CCT, greater preoperative GAT IOP and pseudophakia.