西里西亚·格罗夫诺里(Swingle)C.杰弗里(S.罗汉诺尼),一种来自葫芦科的多年生土著藤本植物,历史上在中国南方对各种疾病的传统疗法中发挥了重要作用。中国卫生部对医药和食品的双重分类强调了其具有广泛应用的潜力。最近的研究揭示了化学成分,药理作用,和罗汉果的毒性。其活性成分包括三萜类,黄酮类化合物,氨基酸,挥发油,多糖,矿物,维生素,和其他微量成分。除了是一种天然甜味剂,罗汉果已被发现具有许多药理作用,包括缓解咳嗽和痰,预防龋齿,发挥抗炎和抗过敏作用,抗衰老和抗氧化,低血糖,降脂,抗抑郁症,抗疲劳,抗精神分裂症,抗帕金森,抗纤维化,和抗肿瘤活性。尽管其多才多艺的潜力,迄今为止,对罗汉果还缺乏系统的研究。本文旨在通过提供主要活性成分的概述来解决这一差距,药理功效,毒性,发展和应用现状,发展困境,以及罗汉果集约开发利用的策略。本文旨在为致力于开发罗汉果生物资源并进一步探索其跨学科潜力的研究人员和从业人员提供指导。
Siraitia grosvenorii (Swingle) C. Jeffrey (S. grosvenorii), a perennial indigenous liana from the Cucurbitaceae family, has historically played a significant role in southern China\'s traditional remedies for various ailments. Its dual classification by the Chinese Ministry of Health for both medicinal and food utility underscores its has the potential of versatile applications. Recent research has shed light on the chemical composition, pharmacological effects, and toxicity of S. grosvenorii. Its active ingredients include triterpenoids, flavonoids, amino acids, volatile oils, polysaccharides, minerals, vitamins, and other microconstituents. Apart from being a natural sweetener, S. grosvenorii has been found to have numerous pharmacological effects, including alleviating cough and phlegm, preventing dental caries, exerting anti-inflammatory and anti-allergic effects, anti-aging and anti-oxidative, hypoglycemic, lipid-lowering, anti-depression, anti-fatigue, anti-schizophrenic, anti-Parkinson, anti-fibrotic, and anti-tumor activities. Despite its versatile potential, there is still a lack of systematic research on S. grosvenorii to date. This paper aims to address this gap by providing an overview of the main active components, pharmacological efficacy, toxicity, current status of development and application, development dilemmas, and strategies for intensive exploitation and utilization of S. grosvenorii. This paper aims to serve as a guide for researchers and practitioners committed to exploiting the biological resources of S. grosvenorii and further exploring its interdisciplinary potential.