近几十年来,许多国家的睾丸癌发病率都在上升。这项研究旨在概述1990年至2019年睾丸癌对中东和北非(MENA)地区的影响,根据年龄组和社会人口指数(SDI)检查其负担。
■发病率数据,死亡,和由于睾丸癌导致的残疾调整寿命年(DALYs)从2019年全球疾病负担研究中检索。报告了计数和年龄标准化率(每100,000人),所有比率均伴有95%的不确定度区间(UI)。
■在MENA,2019年睾丸癌的年龄标准化发病率为1.4/10,000,自1990年以来增加了244.0%.同样,年死亡率,在0.1,在同一时期经历了2.6%的增长。2019年,睾丸癌占3.11万个DALY,年龄标准化率为5.0,比1990年高出2.8%。1-4岁年龄组在2019年的发病率最高。此外,在1990年和2019年,MENA/GlobalDALY比率均高于1-14岁年龄组.在1990年至2019年期间,睾丸癌的年龄标准化DALY率稳步上升,SDI值较高,除了在SDI为0.8时观察到的下降。
■在过去的三十年里,MENA地区的睾丸癌负担显著上升.
UNASSIGNED: The incidence rate of testicular cancer has risen in many countries during recent decades. This study aimed to outline the impact of testicular cancer on the Middle East and North Africa (MENA) region from 1990 to 2019, examining its burden by age group and according to the socio-demographic index (SDI).
UNASSIGNED: Data on the incidence, death, and disability-adjusted life-years (DALYs) due to testicular cancer were retrieved from the Global Burden of Disease study 2019. The counts and age-standardized rates (per 100,000) were reported, and all rates were accompanied by 95% uncertainty intervals (UIs).
UNASSIGNED: In MENA, the age-standardized incidence rate of testicular cancer was 1.4 per 100,000 in 2019, showing a 244.0% increase since 1990. Similarly, the annual death rate, at 0.1, experienced a 2.6% rise during the same period. In 2019, testicular cancer accounted for 31.1 thousand DALYs, marking an age-standardized rate of 5.0, which was 2.8% higher than in 1990. The 1-4 age group exhibited the largest incidence rate in 2019. In addition, in both 1990 and 2019 the MENA/Global DALY ratio was higher than one in the 1-14 year age groups. During the period 1990 to 2019, the age-standardized DALY rate of testicular cancer steadily rose with higher SDI values, except for a decrease observed at an SDI of 0.8.
UNASSIGNED: Over the last thirty years, there has been a notable rise in the burden of testicular cancer in the MENA region.