■茶叶消费被认为对人体健康有益,因为茶叶含有植物化学物质,如多酚和茶黄素。我们对茶叶消费与所有原因死亡率之间的关系进行了系统评价和荟萃分析。心血管疾病(CVD),和癌症,以提供对当前证据的定量评估。
■PubMed,WebofScience,和Scopus数据库在2024年4月进行了搜索,以确定符合条件的研究。随机效应模型用于组合研究特定效应估计(ESs)。
■共有38个前瞻性队列数据集(来自27篇论文),1,956,549名参与者被纳入该荟萃分析。全因死亡率最高和最低的茶消费类别的合并ESs为0.90(95%CI,0.86-0.95),CVD死亡率为0.86(95%CI,0.79-0.94),癌症死亡率为0.90(95%CI,0.78-1.03)。在剂量反应分析中,观察到非线性关联。对于全因死亡率,每天食用2杯(ES,0.91;95%CI,0.88-0.94)和1.5杯/天的癌症死亡率(ES,0.92;95%CI,0.89-0.96),而额外消费并未显示死亡风险的进一步降低.在中等消费水平(1.5-3杯/天)下观察到CVD死亡率的平台期,但在较高摄入水平下观察到死亡风险持续降低.
■适度的茶消费(例如,1.5-2杯/天)与较低的全因相关,CVD,与不喝茶相比,癌症死亡率。需要进一步精心设计的前瞻性研究才能得出明确的结论。
UNASSIGNED: Tea consumption has been considered beneficial to human health because
tea contains phytochemicals such as polyphenols and theaflavins. We conducted a systematic review and meta-analysis on the association between
tea consumption and mortality from all causes, cardiovascular disease (CVD), and cancer to provide a quantitative assessment of current evidence.
UNASSIGNED: The PubMed, Web of Science, and Scopus databases were searched through April 2024 to identify eligible studies. Random effects models were used to combine study-specific effect estimates (ESs).
UNASSIGNED: A total of 38 prospective cohort data sets (from 27 papers) with 1,956,549 participants were included in this meta-analysis. The pooled ESs of the highest versus lowest categories of
tea consumption were 0.90 (95% CI, 0.86-0.95) for all-cause mortality, 0.86 (95% CI, 0.79-0.94) for CVD mortality, and 0.90 (95% CI, 0.78-1.03) for cancer mortality. In the dose-response analysis, a nonlinear association was observed. The greatest risk reductions were observed for the consumption of 2 cups/day for all-cause mortality (ES, 0.91; 95% CI, 0.88-0.94) and 1.5 cups/day for cancer mortality (ES, 0.92; 95% CI, 0.89-0.96), whereas additional consumption did not show a further reduction in the risk of death. A plateau was observed for CVD mortality at moderate consumption levels (1.5-3 cups/day), but a sustained reduction in mortality risk was observed at higher intake levels.
UNASSIGNED: Moderate
tea consumption (e.g., 1.5-2 cups/day) was associated with lower all-cause, CVD, and cancer mortality compared to no
tea consumption. Further well-designed prospective studies are needed for a definitive Conclusion.