背景：植物性脓皮病（PV）是一种病因不明的罕见中性粒细胞性皮肤病。目前,没有PV的治疗指南。全身性类固醇通常用作一线治疗，但在停药或逐渐减少时复发是常见的。材料和方法：我们测试了200mg/d剂量的多西环素治疗耐药性PV的功效。结果：治疗4周后，我们发现PV的临床表现有了显着改善。结论：我们的病例证明了强力霉素作为全身性类固醇保护剂在治疗PV中的潜在用途。
Background: Pyoderma vegetans (PV) is a rare neutrophilic dermatosis of unknown etiology. Currently, there are no treatment guidelines for PV. Systemic steroids are often used as first-line therapy, but recurrence upon discontinuation or tapering is common.Materials and methods: We tested the efficacy of doxycycline at a dose of 200 mg/d to treat resistant PV.Results: After 4 weeks of treatment we noticed a significant improvement in the clinical appearance of PV.Conclusions: Our case demonstrates the potential utility of doxycycline as a systemic steroid-sparing agent in the treatment of PV.
