sugar-sweetened beverages

含糖饮料
  • 文章类型: Journal Article
    目标:许多大学与饮料公司签订倾倒权合同(PRCs),其中一家公司交换赞助款项以获得独家饮料营销权。分别,大学可能有健康饮料倡议(HBIs),以鼓励在校园更健康的选择。这项研究旨在评估PRC如何以及如何频繁地纳入与健康和营养相关的规定,以检查PRC如何支持或破坏HBIs。
    方法:横断面。
    方法:拥有>20,000名学生的美国公立大学。
    方法:2019-2020年从143所大学中的124所获得的131个PRCs。
    方法:主要结果是存在可以鼓励或阻止推广健康饮料的规定(水,无糖汽水,不加糖的咖啡或茶,和100%果汁),以及任何其他明确或暗示提及健康或营养的规定。
    方法:描述性统计。
    结果:公司或大学的12份合同(9%)明确承诺推广健康饮料或遵守营养标准,包括五个承诺支持HBI,四是致力于健康的自动售货政策,和三个描述推广健康饮料品牌的活动。十个(8%)的规定明确禁止水的促进,而55(42%)的规定可以这样解释。11人(8%)包括其他健康和营养规定,例如为未指定的健康活动提供资金。
    结论:大多数大学饮料合同并未明确旨在支持健康的选择,超过一半的规定可能会限制大学实施HBI的能力。当存在时,营养标准较弱。
    OBJECTIVE: Many universities maintain pouring rights contracts (PRCs) with beverage companies wherein one company exchanges sponsorship payments for exclusive beverage marketing rights. Separately, universities may have healthy beverage initiatives (HBIs) to encourage healthier choices on campus. This study aimed to assess how and how frequently PRCs included provisions related to health and nutrition to examine how PRCs may support or undermine HBIs.
    METHODS: Cross-sectional.
    METHODS: U.S. public universities with >20,000 students.
    METHODS: 131 PRCs obtained from 124 of 143 universities in 2019-2020.
    METHODS: Primary outcomes were the presence of provisions that could encourage or discourage promotion of healthy beverages (water, diet soda, unsweetened coffee or tea, and 100% juice), and any other provisions explicitly or implicitly referencing health or nutrition.
    METHODS: Descriptive statistics.
    RESULTS: Twelve contracts (9%) had explicit commitments from the company or university to promote healthy beverages or adhere to nutrition standards, including five committing to support HBIs, four committing to healthy vending policies, and three describing activities to promote healthy beverage brands. Ten (8%) had provisions explicitly inhibiting water promotion and 55 (42%) had provisions that could be interpreted that way. Eleven (8%) included other health and nutrition provisions, such as funding for unspecified wellness activities.
    CONCLUSIONS: Most university beverage contracts did not expressly aim to support healthy choices, and more than half had provisions potentially limiting universities\' ability to implement HBIs. When present, nutrition standards were weak.
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  • 文章类型: Journal Article
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  • 文章类型: Journal Article
    背景:随着全球含糖和非含糖饮料的消费量持续上升,人们越来越担心它们对健康的影响,尤其是孕妇及其后代。
    目的:本研究旨在调查上海孕妇的各种饮料消费模式及其对母亲和后代健康的潜在影响。
    方法:我们采用多阶段随机抽样方法从上海16个地区选择参与者。每个地区分为五个区域。从每个区域随机选择两个城镇,从每个城镇,随机抽取30名孕妇。通过面对面的问卷调查收集数据。还获得了调查后一年内出生的后续数据。
    结果:总饮料的消耗率(TB),含糖饮料(SSB),非糖饮料(NSS)占73.2%,72.8%,和13.5%,分别。Logistic回归分析表明,与非消费者相比,每周服用3次或3次以下TB的孕妇发生妊娠期糖尿病(GDM)的风险增加38.4%(OR=1.384;95%CI:1.129~1.696),发生妊娠期高血压(GH)的风险增加64.2%(OR=1.642;95%CI:1.129~2.389).每周服用4次或更多TB的人面临GDM的风险增加154.3%(OR=2.543;95%CI:2.064-3.314)和GH的风险增加169.3%(OR=2.693;95%CI:1.773-4.091)。在SSB的分析中观察到类似的结果。关于后代的健康,与非消费者相比,每周服用4次或更多TB与巨大儿(OR=2.143;95%CI:1.304-3.522)和胎龄大(LGA)(OR=1.695;95%CI:1.219-2.356)的风险大幅增加相关。在对NSS的分析中,巨大儿(OR=6.581;95%CI:2.796-13.824)和LGA(OR=7.554;95%CI:3.372-16.921)的风险显着增加。
    结论:上海孕妇的饮料消费水平较高,值得关注。过量饮用饮料会增加GDM和GH的风险,而过度消耗NSS可能对后代巨大儿和LGA有较大影响。
    BACKGROUND: As the global consumption of sugary and non-sugar sweetened beverages continues to rise, there is growing concern about their health impacts, particularly among pregnant women and their offspring.
    OBJECTIVE: This study aimed to investigate the consumption patterns of various beverages among pregnant women in Shanghai and their potential health impacts on both mothers and offspring.
    METHODS: We applied a multi-stage random sampling method to select participants from 16 districts in Shanghai. Each district was categorised into five zones. Two towns were randomly selected from each zone, and from each town, 30 pregnant women were randomly selected. Data were collected through face-to-face questionnaires. Follow-up data on births within a year after the survey were also obtained.
    RESULTS: The consumption rates of total beverages (TB), sugar-sweetened beverages (SSB), and non-sugar sweetened beverages (NSS) were 73.2%, 72.8%, and 13.5%, respectively. Logistic regression analysis showed that compared to non-consumers, pregnant women consuming TB three times or less per week had a 38.4% increased risk of gestational diabetes mellitus (GDM) (OR = 1.384; 95% CI: 1.129-1.696) and a 64.2% increased risk of gestational hypertension (GH) (OR = 1.642; 95% CI: 1.129-2.389). Those consuming TB four or more times per week faced a 154.3% higher risk of GDM (OR = 2.543; 95% CI: 2.064-3.314) and a 169.3% increased risk of GH (OR = 2.693; 95% CI: 1.773-4.091). Similar results were observed in the analysis of SSB. Regarding offspring health, compared to non-consumers, TB consumption four or more times per week was associated with a substantial increase in the risk of macrosomia (OR = 2.143; 95% CI: 1.304-3.522) and large for gestational age (LGA) (OR = 1.695; 95% CI: 1.219-2.356). In the analysis of NSS, with a significantly increased risk of macrosomia (OR = 6.581; 95% CI:2.796-13.824) and LGA (OR = 7.554; 95% CI: 3.372-16.921).
    CONCLUSIONS: The high level of beverage consumption among pregnant women in Shanghai needs attention. Excessive consumption of beverages increases the risk of GDM and GH, while excessive consumption of NSS possibly has a greater impact on offspring macrosomia and LGA.
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  • 文章类型: Journal Article
    目的:量化儿童和青少年的全球含糖饮料(SSB)摄入量和随时间的趋势。
    方法:基于人群的研究。
    方法:全球膳食数据库。
    方法:1990年至2018年期间,185个国家3-19岁的儿童和青少年,按年龄在国家以下级别进行联合分层,性别,父母教育,农村或城市住宅。
    结果:2018年,南亚的全球SSB平均摄入量为3.6(标准化服务=248g(8oz))/周(1.3(95%不确定区间1.0至1.9),拉丁美洲和加勒比地区为9.1(8.3至10.1)。年龄较大的儿童和青少年的SSB摄入量高于年龄较小的儿童和青少年,那些居住在城市和农村地区的人,以及受教育程度较高与较低的父母。在1990年至2018年期间,全球SSB平均摄入量增加了0.68份/周(22.9%),撒哈拉以南非洲地区涨幅最大(2.17份/周;106%)。在分析中包括的185个国家中,56(30.3%)的平均SSB摄入量≥7份/周,代表2.38亿儿童和青少年,占全球青年人口的10.4%。
    结论:这项研究发现,从1990年到2018年,185个国家3-19岁儿童和青少年的SSB摄入量增加了23%,与全球肥胖患病率的上升平行。SSB摄入量在全球儿童和青少年之间以及年龄之间显示出很大的异质性,父母的教育水平,和城市化。这项研究应该有助于为减少年轻人摄入SSB的政策提供信息,特别是拉丁美洲和加勒比城市和农村地区所有教育水平的学生,以及撒哈拉以南非洲日益严重的SSB对公共卫生的影响。
    To quantify global intakes of sugar sweetened beverages (SSBs) and trends over time among children and adolescents.
    Population based study.
    Global Dietary Database.
    Children and adolescents aged 3-19 years in 185 countries between 1990 and 2018, jointly stratified at subnational level by age, sex, parental education, and rural or urban residence.
    In 2018, mean global SSB intake was 3.6 (standardized serving=248 g (8 oz)) servings/week (1.3 (95% uncertainly interval 1.0 to 1.9) in south Asia to 9.1 (8.3 to 10.1) in Latin America and the Caribbean). SSB intakes were higher in older versus younger children and adolescents, those resident in urban versus rural areas, and those of parents with higher versus lower education. Between 1990 and 2018, mean global SSB intakes increased by 0.68 servings/week (22.9%), with the largest increases in sub-Saharan Africa (2.17 servings/week; 106%). Of 185 countries included in the analysis, 56 (30.3%) had a mean SSB intake of ≥7 servings/week, representing 238 million children and adolescents, or 10.4% of the global population of young people.
    This study found that intakes of SSBs among children and adolescents aged 3-19 years in 185 countries increased by 23% from 1990 to 2018, parallel to the rise in prevalence of obesity among this population globally. SSB intakes showed large heterogeneity among children and adolescents worldwide and by age, parental level of education, and urbanicity. This research should help to inform policies to reduce SSB intake among young people, particularly those with larger intakes across all education levels in urban and rural areas in Latin America and the Caribbean, and the growing problem of SSBs for public health in sub-Saharan Africa.
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  • 文章类型: Journal Article
    目标:实施卫生税收政策以控制有害商品的消费和改善公共卫生成果的努力已在全球范围内得到了广泛认可。然而,它们的成功采用仍然是一项复杂的努力。这调查了围绕卫生税实施的挑战和机遇,特别关注印度尼西亚的地方政府,卫生税的权力下放背景仍未得到充分研究。
    方法:采用定性方法,使用问题驱动的政治经济学分析方法。
    方法:我们正在从2022年7月至9月在三个省-Lampung进行的总共12个焦点小组讨论(FGD)中收集数据,日惹和巴厘岛的特别地区/DaerahIstimewa,每个选择代表一种特定的商品:烟草,含糖饮料(SSB)和酒精饮料-我们探讨了卫生税收政策的多方面动态。
    方法:这些FGD涉及每个FGD的平均10名参与者,代表政府机构,非政府组织和消费者。
    结果:我们的研究结果表明,卫生税收政策有可能对公共卫生做出重大贡献。消费者了解烟草的健康风险,文化因素影响烟草和酒精消费。对于SSB,消费者缺乏对长期健康风险的认识令人担忧。最后,官僚主义的复杂和分散的政府阻碍了这三种商品的实施。
    结论:此外,这项研究强调了有效政策沟通的重要性。它强调了为公共卫生举措指定健康税收入的重要性。它还加强了将卫生税视为一项干预措施的必要性,这是全面公共卫生方法的一部分,包括广告限制和标准化包装等补充非财政措施。应对这些挑战对于充分发挥卫生税收政策的潜力至关重要。
    OBJECTIVE: Efforts to implement health tax policies to control the consumption of harmful commodities and enhance public health outcomes have garnered substantial recognition globally. However, their successful adoption remains a complex endeavour. This investigates the challenges and opportunities surrounding health tax implementation, with a particular focus on subnational government in Indonesia, where the decentralisation context of health tax remains understudied.
    METHODS: Employing a qualitative methodology using a problem-driven political economy analysis approach.
    METHODS: We are collecting data from a total of 12 focus group discussions (FGDs) conducted between July and September 2022 in three provinces-Lampung, Special Region of/Daerah Istimewa Yogyakarta and Bali, each chosen to represent a specific commodity: tobacco, sugar-sweetened beverages (SSBs) and alcoholic beverages-we explore the multifaceted dynamics of health tax policies.
    METHODS: These FGDs involved a mean of 10 participants in each FGD, representing governmental institutions, non-governmental organisations and consumers.
    RESULTS: Our findings reveal that health tax policies have the potential to contribute significantly to public health. Consumers understand tobacco\'s health risks, and cultural factors influence both tobacco and alcohol consumption. For SSBs, the consumers lack awareness of long-term health risks is concerning. Finally, bureaucratic complexiting and decentralised government hinder implementation for all three commodities.
    CONCLUSIONS: Furthermore, this study underscores the importance of effective policy communication. It highlights the importance of earmarking health tax revenues for public health initiatives. It also reinforces the need to see health taxes as one intervention as part of a comprehensive public health approach including complementary non-fiscal measures like advertising restrictions and standardised packaging. Addressing these challenges is critical for realising the full potential of health tax policies.
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  • 文章类型: Journal Article
    本研究旨在使用全球疾病负担(GBD)研究2019年的数据,量化60岁及以上成年人高糖饮料(SSB)的全球心血管疾病(CVD)负担。
    我们提取了有关CVD死亡率的数据,残疾调整寿命年(DALYs),以及来自GBD2019研究的60岁及以上人群的风险因素暴露。使用年龄-时期-队列模型来估计死亡率和DALY率的总体年度百分比变化(净漂移,每年%),1990年至2019年各年龄组的死亡率和死亡率(局部漂移,每年%),校正周期偏差(年龄效应)的纵向特定年龄比率,以及1990年至2019年各年龄组的死亡率和戴利率(局部漂移,%/年)。和周期/队列相对风险(周期/队列效应)。
    在1990年至2019年期间,由于高SSB摄入量而导致的全球年龄标准化CVD死亡率(ASMR)和残疾调整寿命年(DALY)下降。高SDI地区的降幅更大。ASMR从19.5降至13/100,000(估计年度百分比变化(EAPC):-1.46%),ASDR从345.8降至220.6/100,000(EAPC:-1.66%)。年龄时期队列分析显示,CVD死亡和DALYs随年龄呈指数增长,在85-89年达到顶峰。经期影响表明,自1999年以来,CVD死亡率和DALY率下降,特别是在SDI较高的地区。队列效应表明,在1900年至1959年间出生的连续几代人中,风险持续下降。预测表明,到2045年,全球将继续下降,但在SDI较低的地区下降速度较慢。
    总而言之,这项对由高SSB摄入量引起的老年人全球CVD负担的综合评估突出了重大成就,但也突出了需要关注的持续领域.有利的死亡率下降和DALY率趋势反映了在人口增长和老龄化期间CVD控制的实质性进展。
    UNASSIGNED: This study aimed to quantify the global cardiovascular disease (CVD) burden attributable to diet high in sugar-sweetened beverages (SSB) among adults aged 60 years and older using data from the Global Burden of Disease (GBD) Study 2019.
    UNASSIGNED: We extracted data on CVD mortality, disability-adjusted life-years (DALYs), and risk-factor exposures from the GBD 2019 study for people aged 60 and older. Age-period-cohort models were used to estimate the overall annual percentage change in mortality and DALY rate (net drift, % per year), mortality and DALY rate for each age group from 1990 to 2019 (local drift, % per year), longitudinal age-specific rate corrected for period bias (age effect), and mortality and Daly rate for each age group from 1990 to 2019 (local drift, % per year). And period/cohort relative risk (period/cohort effect).
    UNASSIGNED: Between 1990 and 2019, global age-standardized CVD mortality (ASMR) and disability-adjusted life years (DALY) rates attributable to high SSB intake decreased, with larger reductions in high-SDI regions. ASMR declined from 19.5 to 13 per 100,000 (estimated annual percentage change (EAPC): -1.46%) and ASDR declined from 345.8 to 220.6 per 100,000 (EAPC: -1.66%). Age-period-cohort analysis showed CVD deaths and DALYs increased exponentially with age, peaking at 85-89 years. Period effects indicated declining CVD mortality and DALY rates since 1999, especially in higher-SDI regions. Cohort effects demonstrated consistent risk declines across successive generations born between 1900 and 1959. Predictions suggest continuing decreases through 2045 globally, but slower declines in lower-SDI regions.
    UNASSIGNED: In conclusion, this comprehensive assessment of global CVD burden among older adults attributable to high SSB intake highlights major achievements but also persistent areas needing attention. Favorable declining mortality and DALY rate trends reflect substantial progress in CVD control amid population growth and aging.
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  • 文章类型: Journal Article
    需要膳食摄入的客观生物标志物来推进营养研究。碳稳定同位素比(C13/C12;CIR)有望作为添加糖(AS)和加糖饮料(SSB)摄入量的客观生物标志物。这项系统的范围审查提供了人类研究中有关CIRs的最新证据。搜索结果(至2024年4月12日)产生了6,297项研究和24篇最终文章。研究是观察性的(n=12),控制进料(n=10),或饮食干预(n=2)。CIRs从血液中取样(n=23),头发(n=5),呼吸(n=2),和/或脂肪组织(n=1)。大多数(n=17)进行了整个组织(即,批量)分析,八种使用的化合物特定同位素分析(CSIA),和/或两项研究使用了适合分析呼吸的方法。在美国三个集中的地理区域进行了研究(n=7弗吉尼亚州;n=5亚利桑那州;n=4阿拉斯加),只有两项研究在其他国家进行。使用CSIA检查非必需氨基酸丙氨酸的CIR(CIR-Ala;n=4)和呼吸分析的CIR(n=2)的研究为CIR作为AS和SSB的客观生物标志物提供了最有力的证据(R2范围为0.36-0.91)。使用大量头发或血液分析的研究显示阳性,但与AS和SSB的相关性不大,差异较大(R2范围为0.05-0.48)。很少有研究表明没有关联,特别是在非美国人群以及AS和SSB摄入量较低的人群中。两项研究为CIR检测饮食干预对SSB摄入量的影响提供了证据。总的来说,最有说服力的证据支持CIR-Ala作为AS摄入量的客观指标,呼吸CIR作为短期AS摄入量的指标.考虑如何调整基本的饮食模式仍然是未来工作的重要领域,使用呼吸和CSIA的新兴方法值得进一步研究。需要更多的证据来完善CIRs测量AS和SSB摄入量的实用性和特异性。
    Objective biomarkers of dietary intake are needed to advance nutrition research. The carbon stable isotope ratio (C13/C12; CIR) holds promise as an objective biomarker of added sugar (AS) and sugar-sweetened beverage (SSB) intake. This systematic scoping review presents the current evidence on CIRs from human studies. Search results (through April 12, 2024) yielded 6,297 studies and 24 final articles. Studies were observational (n=12), controlled feeding (n=10), or dietary interventions (n=2). CIRs were sampled from blood (n=23), hair (n=5), breath (n= 2), and/or adipose tissue (n=1). Most (n=17) conducted whole tissue (i.e., bulk) analysis, eight used compound specific isotope analysis (CSIA), and/or two studies used methods appropriate for analyzing breath. Studies were conducted in three concentrated geographic regions of the U.S. (n=7 Virginia; n=5 Arizona; n=4 Alaska), with only two studies conducted in other countries. Studies that used CSIA to examine the CIR from the non-essential amino acid alanine (CIR-Ala; n=4) and CIR analyzed from breath (n=2) provided the most robust evidence for CIR as an objective biomarker of AS and SSBs (R2 range 0.36-0.91). Studies using bulk analysis of hair or blood showed positive, but modest and more variable associations with AS and SSBs (R2 range 0.05-0.48). Few studies showed no association, particularly in non-U.S. populations and those with low AS and SSB intakes. Two studies provided evidence for CIR to detect changes in SSB intake in response to dietary interventions. Overall, the most compelling evidence supports CIR-Ala as an objective indicator of AS intake and breath CIR as an indicator of short term AS intake. Considering how to adjust for underlying dietary patterns remains an important area of future work and emerging methods using breath and CSIA warrant additional investigation. More evidence is needed to refine the utility and specificity of CIRs to measure AS and SSB intake.
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  • 文章类型: Journal Article
    对含糖饮料(SSB)分销商征收消费税,随后传递给消费者,是一项旨在降低心脏代谢疾病高患病率并产生公共卫生资金的政策。税收与较低的SSB购买和消费相关,但目前尚不清楚它们是否与青少年体重相关结局相关.
    确定SSB消费税与青年体重指数(BMI)轨迹的关联。
    这项队列研究于2009年至2020年进行,包括税收实施前6年和税收实施后4至6年。加州城市奥尔巴尼,伯克利,奥克兰,旧金山,实施SSB消费税,与加利福尼亚州40个人口统计学上匹配的控制城市进行了比较。参与者包括2至19岁的KaiserPermanente成员(基线),他们连续居住在选定的城市,其电子健康记录中记录了至少1个税前和1个税后BMI。数据分析于2021年1月至2023年5月进行。
    实施SSB消费税。
    将疾病控制和预防中心的年龄和性别特定的BMI百分位数以及实施后4至6年的税收实施前超重或肥胖青年的百分比与对照城市进行比较。使用差异差异(DID)方法进行统计分析。使用综合控制方法进行敏感性分析。
    总共44771名青年(基线时的平均[SD]年龄,6.4[4.2]岁;22337名女性[49.9%])居住在有SSB税的城市;345428名青年(平均[SD]年龄,6.9[4.2]岁;1710168名女性[49.5%])居住在控制城市。SSB税收实施后,暴露城市和控制城市之间的BMI百分位数平均变化总体差异为-1.64个百分点(95%CI,-3.10至-0.17个百分点)。与对照城市相比,超重或肥胖青年或肥胖青年的百分比没有显着总体差异。就BMI百分位数而言,所有DID估计对居住在暴露城市的年轻人都很重要(2017年年龄2-5岁,-2.06个百分点[95%CI,-4.04至-0.09个百分点];2017年年龄6-11岁,-2.79个百分点[95%CI,-4.29至-1.30个百分点]),超重或肥胖青年的百分比(2-5岁,-5.46个百分点[95%CI,-8.47至-2.44个百分点];年龄6-11岁,-4.23个百分点[95%CI,-6.90至-1.57个百分点]),以及肥胖青年的百分比(年龄2-5岁;-1.87个百分点[95%CI,-3.36至-0.38个百分点];年龄6-11岁,-1.85个百分点[95%CI,-3.46至-0.24个百分点])。与控制城市相比,男性的平均BMI百分位数变化显着(-1.98个百分点;95%CI,-3.48至-0.48个百分点),亚洲(-1.63个百分点;95%CI,-3.10至-0.16个百分点),和怀特(-2.58个百分点;95%CI,-4.11至-1.10个百分点)青年。与控制城市相比,暴露城市中的白人青年超重或肥胖的百分比(-3.73个百分点;95%CI,-6.11至-1.35个百分点)和肥胖的百分比(-2.78个百分点;95%CI,-4.18至-1.37个百分点)有所改善。
    在这项队列研究中,SSB消费税与青少年BMI百分位数较低相关。政策制定者应考虑实施SSB消费税,以防止或减少青少年超重和肥胖,最终,慢性疾病,尤其是12岁以下的儿童。
    UNASSIGNED: Levying excise taxes on sugar-sweetened beverage (SSB) distributors, which are subsequently passed on to consumers, is a policy implemented to reduce the high prevalence of cardiometabolic disease and generate public health funding. Taxes are associated with lower SSB purchases and consumption, but it is unknown whether they are associated with weight-related outcomes in youth.
    UNASSIGNED: To determine the association of SSB excise taxes with youth body mass index (BMI) trajectories.
    UNASSIGNED: This cohort study was conducted from 2009 to 2020, including 6 years before tax implementation and 4 to 6 years after tax implementation. The California cities of Albany, Berkeley, Oakland, and San Francisco, which implemented SSB excise taxes, were compared against 40 demographically matched control cities in California. Participants included Kaiser Permanente members aged 2 to 19 years at cohort entry (baseline) with continuous residence in selected cities with at least 1 pretax and 1 posttax BMI recorded in their electronic health record. Data analysis was performed from January 2021 to May 2023.
    UNASSIGNED: Implementation of SSB excise taxes.
    UNASSIGNED: Centers for Disease Control and Prevention age-specific and sex-specific BMI percentiles and percentage of youth with overweight or obesity before tax implementation through 4 to 6 years after implementation were compared with control cities. Statistical analysis was conducted using the difference-in-differences (DID) method. A sensitivity analysis used the synthetic control method.
    UNASSIGNED: A total of 44 771 youth (mean [SD] age at baseline, 6.4 [4.2] years; 22 337 female [49.9%]) resided in the cities with SSB taxes; 345 428 youth (mean [SD] age, 6.9 [4.2] years; 171 0168 female [49.5%]) resided in control cities. There was a -1.64-percentage point (95% CI, -3.10 to -0.17 percentage points) overall difference in the mean change of BMI percentile between exposure and control cities after SSB tax implementation. There was no significant overall difference in the percentage of youth with overweight or obesity or youth with obesity compared with control cities. All DID estimates were significant for youth residing in exposure cities in terms of BMI percentile (age 2-5 years in 2017, -2.06 percentage points [95% CI, -4.04 to -0.09 percentage points]; age 6-11 years in 2017, -2.79 percentage points [95% CI, -4.29 to -1.30 percentage points]), percentages of youth with overweight or obesity (age 2-5 years, -5.46 percentage points [95% CI, -8.47 to -2.44 percentage points]; age 6-11 years, -4.23 percentage points [95% CI, -6.90 to -1.57 percentage points]), and percentages of youth with obesity (age 2-5 years; -1.87 percentage points [95% CI, -3.36 to -0.38 percentage points]; age 6-11 years, -1.85 percentage points [95% CI, -3.46 to -0.24 percentage points]). Compared with control cities, changes in mean BMI percentiles were significant for male (-1.98 percentage points; 95% CI, -3.48 to -0.48 percentage points), Asian (-1.63 percentage points; 95% CI, -3.10 to -0.16 percentage points), and White (-2.58 percentage points; 95% CI, -4.11 to -1.10 percentage points) youth. Compared with control cities, White youth in exposure cities had improvements in the percentage with overweight or obesity (-3.73 percentage points; 95% CI, -6.11 to -1.35 percentage points) and the percentage with obesity (-2.78 percentage points; 95% CI, -4.18 to -1.37 percentage points).
    UNASSIGNED: In this cohort study, SSB excise taxes were associated with lower BMI percentile among youth. Policymakers should consider implementing SSB excise taxes to prevent or reduce youth overweight and obesity and, ultimately, chronic disease, particularly among children younger than 12 years.
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  • 文章类型: Journal Article
    背景:黑人/白人心脏病死亡率差异在1980年代初开始增加,与美国食品供应中从蔗糖转换为高果糖玉米糖浆/(HFCS)相吻合。HFCS中的果糖比公认的安全/GRAS多,这导致了食品/饮料中前所未有的游离果糖/(未配对的果糖)过量。平均人均过量游离果糖,从HFCS,在1980年代初开始超过引发果糖吸收不良的剂量/(5-10克)。果糖吸收不良会导致膳食肽/肠促胰岛素/(GLP-1/GIP)的肠道生态失调和肠道原位果糖糖基化,从而形成动脉粥样硬化的晚期糖基化终产物。两者都失调肠道内分泌功能,并且是心血管疾病/(CVD)的危险因素。有限的研究表明,非洲裔美国人比其他人有更高的果糖吸收不良患病率。CVD风险在生命早期开始。
    方法:从1985-86年开始的成人冠状动脉风险发展/(CARDIA)研究数据,有2186名黑人和2277名白人参与者,年龄18-30岁,用于检验HFCS甜味饮料摄入量增加CVD风险/发生率的假设,黑人比白人年轻人更多,和较低的摄入量;而橙汁-一种低过量的无果糖果汁,具有可比的总糖和总果糖,但是果糖和葡萄糖的比例是1:1,即,低过量游离果糖,不。Cox比例风险模型用于计算风险比。
    结果:与吸烟(HR=1.6)相比,摄入HFCS甜味饮料与更高的CVD风险(HR=1.7)相关。在HFCS甜味饮料摄入量较低的情况下,黑人参与者的CVD风险高于白人参与者。Intake,低至3次/周,与CVD风险的两倍相关不太频繁/从不,仅在黑人参与者中(HR2.1,95%CI1.2-3.7;P=0.013)。有序关系的概率接近意义。在黑人参与者中,CVD发病率从59.8/1000跃升62%,≤2次/周,至96.9/1000,在3-6倍/周的消费者中。在白人参与者中,CVD发病率从37.6/1000增加,≤1.5倍/周,至41.1/1000,其中2倍/周-一次/天-增加9%。在黑色每日HFCS加糖饮料消费者中,高血压最高。
    结论:过去40年来,HFCS的普遍存在,果糖与葡萄糖的比例高于公认的安全水平,可能导致了心血管疾病的种族差异,由于黑人个体中果糖吸收不良的患病率较高,未配对/过量的游离果糖诱导的肠道菌群失调和膳食肽/肠促胰岛素(GLP-1/GIP)的肠道果糖糖基化。这些紊乱导致动脉粥样硬化斑块;促进肠促胰岛素功能不全/失调/饱腹感改变/血糖异常;减少保护性微生物群代谢物;并增加高血压,CVD发病率和死亡率。
    BACKGROUND: The black/white heart disease mortality disparity began increasing in the early 1980\'s, coincident with the switch from sucrose to high-fructose-corn-syrup/(HFCS) in the US food supply. There has been more fructose in HFCS than generally-recognized-as-safe/GRAS, which has contributed to unprecedented excess-free-fructose/(unpaired-fructose) in foods/beverages. Average- per-capita excess-free-fructose, from HFCS, began exceeding dosages/(5-10 g) that trigger fructose-malabsorption in the early 1980\'s. Fructose malabsorption contributes to gut-dysbiosis and gut-in-situ-fructosylation of dietary peptides/incretins/(GLP-1/GIP) which forms atherosclerotic advanced-glycation-end-products. Both dysregulate gut endocrine function and are risk factors for cardiovascular disease/(CVD). Limited research shows that African Americans have higher fructose malabsorption prevalence than others. CVD risk begins early in life.
    METHODS: Coronary-Artery-Risk-Development-in-Adults/(CARDIA) study data beginning in 1985-86 with 2186 Black and 2277 White participants, aged 18-30 y, were used to test the hypothesis that HFCS sweetened beverage intake increases CVD risk/incidence, more among Black than White young adults, and at lower intakes; while orange juice-a low excess-free-fructose juice with comparable total sugars and total fructose, but a 1:1 fructose-to-glucose-ratio, i.e., low excess-free-fructose, does not. Cox proportional hazards models were used to calculate hazard ratios.
    RESULTS: HFCS sweetened beverage intake was associated with higher CVD risk (HR = 1.7) than smoking (HR = 1.6). CVD risk was higher at lower HFCS sweetened beverage intake among Black than White participants. Intake, as low as 3 times/wk, was associated with twice the CVD risk vs. less frequent/never, among Black participants only (HR 2.1, 95% CI 1.2-3.7; P = 0.013). Probability of an ordered relationship approached significance. Among Black participants, CVD incidence jumped 62% from 59.8/1000, among ≤ 2-times/wk, to 96.9/1000 among 3-6 times/wk consumers. Among White participants, CVD incidence increased from 37.6/1000, among ≤ 1.5-times/wk, to 41.1/1000, among 2 times/wk-once/d - a 9% increase. Hypertension was highest among Black daily HFCS sweetened beverage consumers.
    CONCLUSIONS: The ubiquitous presence of HFCS over-the-past-40 years, at higher fructose-to-glucose ratios than generally-recognized-as-safe, may have contributed to CVD racial disparities, due to higher fructose-malabsorption prevalence among Black individuals, unpaired/excess-free-fructose induced gut dysbiosis and gut fructosylation of dietary peptides/incretins (GLP-1/GIP). These disturbances contribute to atherosclerotic plaque; promote incretin insufficiency/dysregulation/altered satiety/dysglycemia; decrease protective microbiota metabolites; and increase hypertension, CVD morbidity and mortality.
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  • 文章类型: Journal Article
    背景:评估含糖饮料(SSB)税收通常依赖于模拟模型。我们以德国为例,评估了对SSB税收的反应的假设如何影响与2型糖尿病(T2DM)相关的预计体重变化以及随后的健康和经济影响。
    方法:在主要分析中,我们使用边际价格弹性(PE)估算了德国按年龄和性别对SSB征收20%增值税时能量摄入的变化,并应用能量均衡模型预测体重变化.然后,我们量化了几个假设修改的影响:SSB自身PE调整为消费(M1)/基于替代荟萃分析(M2);SSB消费调整为漏报(M3);通过边际替代(M4a)或调整(M4b)交叉PE/卡路里变化的百分比(M4c)。我们还评估了替代税率为10%(S1)或30%(S2)的情况,包括果汁(S3)。我们计算了每个修改和情景的超重和肥胖率。我们模拟了对T2DM的影响,相关的医疗保健费用,和残疾调整寿命年(DALYs)在2011年德国成年人口的一生中使用马尔可夫模型。数据包括官方人口统计,全国调查,和荟萃分析。
    结果:在德国征收20%的增值税可以使肥胖的男性和女性人数减少210,800[138,800;294,100]和80,800[45,100;123,300],分别。在人口的一生中,这将导致适度的T2DM相关的健康和经济影响(避免了76,700个DALYs[42,500;120,600];节省了23.7亿欧元[1.33;3.71]的成本).政策影响因修改而变化很大(均为DALYs):(M1)94,800[51,500;150,700];(M2)164,200[99,500;243,500];(M3)52,600[22,500;91,100];(M4a)-18,100[-111,500;68,300];(M4b)25,800与修改有关的政策影响的可变性类似于替代政策方案之间的可变性(全部避免了DALYs):(S1)26,400[9,300;47,600];(S2)126,200[73,600;194,500];(S3)342,200[234,200;430,400]。
    结论:在SSB征税下预测的体重减轻对研究人员由于数据限制而经常需要的假设很敏感。因为这种可变性传播到对健康和经济影响的估计,在决策中使用结果时,应考虑由此产生的结构不确定性。
    BACKGROUND: Evaluating sugar-sweetened beverage (SSB) taxation often relies on simulation models. We assess how assumptions about the response to SSB taxation affect the projected body weight change and subsequent health and economic impacts related to type 2 diabetes mellitus (T2DM) using Germany as an example.
    METHODS: In the main analysis, we estimated changes in energy intake by age and sex under a 20% value-added tax on SSBs in Germany using marginal price elasticities (PE) and applied an energy equilibrium model to predict body weight changes. We then quantified the impact of several assumption modifications: SSB own-PE adjusted for consumption (M1)/based on alternative meta-analysis (M2); SSB consumption adjusted for underreporting (M3); substitution via marginal (M4a) or adjusted (M4b) cross-PE/as % of calorie change (M4c). We also assessed scenarios with alternative tax rates of 10% (S1) or 30% (S2) and including fruit juice (S3). We calculated overweight and obesity rates per modification and scenario. We simulated the impact on T2DM, associated healthcare costs, and disability-adjusted life years (DALYs) over the lifetime of the 2011 German adult population with a Markov model. Data included official demographics, national surveys, and meta-analyses.
    RESULTS: A 20% value-added tax in Germany could reduce the number of men and women with obesity by 210,800 [138,800; 294,100] and 80,800 [45,100; 123,300], respectively. Over the population\'s lifetime, this would lead to modest T2DM-related health and economic impacts (76,700 DALYs [42,500; 120,600] averted; €2.37 billion [1.33; 3.71] costs saved). Policy impacts varied highly across modifications (all in DALYs averted): (M1) 94,800 [51,500; 150,700]; (M2) 164,200 [99,500; 243,500]; (M3) 52,600 [22,500; 91,100]; (M4a) -18,100 [-111,500; 68,300]; (M4b) 25,800 [-31,400; 81,500]; (M4c) 46,700 [25,300; 77,200]. The variability in policy impact related to modifications was similar to the variability between alternative policy scenarios (all in DALYs averted): (S1) 26,400 [9,300; 47,600]; (S2) 126,200 [73,600; 194,500]; (S3) 342,200 [234,200; 430,400].
    CONCLUSIONS: Predicted body weight reductions under SSB taxation are sensitive to assumptions by researchers often needed due to data limitations. Because this variability propagates to estimates of health and economic impacts, the resulting structural uncertainty should be considered when using results in decision-making.
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