背景与目的皮肤癌是全世界最常见的癌症。据报道,区域差异会影响人口统计学和非黑色素瘤皮肤癌的患病率;此外,非黑色素瘤皮肤癌被认为被低估了。在这项研究中,我们的目标是在苏格兰高地的农村中心识别和强调皮肤癌的任何可能的显著特征。方法本研究是一项回顾性研究,分析和报告一年来在我们农村中心切除的所有皮肤病变中的癌性皮肤病变切除率及其特征。收集了参加我们服务的可疑皮肤病变切除患者的临床和组织病理学数据。数据包括患者的年龄,性别,病变的诊断,site,尺寸,颜色,边界,切除边缘,复发,和并发症。创建了一个数据库,创建了两个队列:癌症和非癌性病变组,使用学生T检验和Z检验比较两个队列的数据.如果<0.5,则P值被认为是统计学显著的。对总体数据进行分析,揭示趋势和最终结果。结果2019年12月至2020年12月,96例患者行皮损切除术,30%是癌变的。基底细胞癌是最常见的恶性生长,占所有切除恶性病变的76.7%。在20%和3.3%的恶性病变患者中发现鳞状细胞癌和黑色素瘤,分别。在总数中,76%的癌性病变为男性。最常见的部位是头颈部(58.8%)。头颈部高危病变(P=0.00988),在74.5岁以上的老年人中(P=0.000037),男性(P=0.001)。结论基底细胞癌是最常见的恶性病变。头颈部有病变的老年男性患癌症的风险更高。涉及全科医生的大型多中心研究可能需要进一步澄清,这可能有助于识别区域差异。
Background & Aim Skin cancer is the most common cancer around the world. Regional differences have been reported affecting the demographics and the prevalence of non-melanoma skin cancers; furthermore, non-melanoma skin cancers are believed to be underreported. In this study, we aim to identify and highlight any possible significant characteristics of skin cancer in our rural center in Scotland\'s Highlands. Methods This is a retrospective study analyzing and reporting cancerous skin lesions excision rates among all skin lesions excised and their characteristics in our rural center for one year. Clinical and histopathological data for patients attending our services for suspicious skin lesions excision were collected. Data included the patient\'s age, gender, lesion\'s diagnosis, site, size, color, borders, resection edges, recurrence, and complications. A database was created creating two cohorts: cancer and non-cancerous lesions groups, both cohorts\' data was compared using student T-tests and Z-tests. P-values were considered statistically significant if < 0.5, Overall data was analyzed revealing trends and end results. Results From December 2019 to December 2020, 96 patients underwent skin lesions excision, 30% were cancerous. Basal cell carcinoma was the most common malignant growth standing for 76.7% of all malignant lesions excised. Squamous cell carcinoma and melanoma were found in 20% and 3.3% of patients with malignant lesions, respectively. Out of the total, 76% of cancerous lesions were in males. The most common site was head and neck (58.8%). High-risk lesions were the ones on the head and neck (P= 0.00988), in the elderly over 74.5 years (P= 0.000037), and males (P= 0.001). Conclusion Basal cell carcinoma was the most common malignant lesion. Elderly men with lesions on the head and neck had higher risks for cancer. Further clarification may be required with larger multi-center studies involving general practitioners, which might help identify regional variations.