PDF(Pubmed)
Abstract：
Atypical fibroxanthoma (AFX) is a rare spindle cell proliferation arising from significant sun exposure. AFX often appears as a red papule, typically found in the head and neck region of elderly patients. Since there is no specificity in immunohistology, various stains differentiate AFX from other skin cancers. The stains include cluster of differentiation 68 (CD68), cluster of differentiation 163 (CD163), vimentin, cytokeratin epithelial (CKAE), and melanin. While local recurrence is common, AFX rarely metastasizes. Thus, the treatment options are complete surgical excision or micrographically oriented histographic surgery.
摘要：
非典型纤维黄瘤（AFX）是一种罕见的梭形细胞增殖，由大量阳光照射引起。AFX通常表现为红色丘疹，常见于老年患者的头颈部。由于免疫组织学没有特异性，各种染色将AFX与其他皮肤癌区分开。染色剂包括分化簇68(CD68)，分化簇163（CD163），波形蛋白,细胞角蛋白上皮（CKAE），还有黑色素.虽然局部复发很常见，AFX很少转移。因此，治疗方案是完整的手术切除或以显微照片为导向的直方图手术。
