目的:鼻窦恶性肿瘤是一组罕见的头颈部肿瘤。我们旨在根据接受放疗的患者的组织学类型报告肿瘤学结果。
方法:在这项单机构研究中,我们回顾性检索并分析了2011-2016年期间接受放疗作为治疗一部分的鼻腔鼻窦癌患者的资料.当地的3年期利率,区域,和遥远的复发,根据组织学类型评估总生存期。
结果:本研究共评估了28例患者,其中大多数是男性(60%)。鳞状细胞癌(SCC),腺样囊性癌(ACC),腺癌(ADC)15例(53.5%),8(28.5%),和5(18%),分别。局部和区域复发率最高的是ACC和SCC,分别。远处复发在ADC中更常见。三年OS为48%,50%,和73%的SCC,ADC,ACC,分别。
结论:不同的鼻窦癌组织病理学表现出不同的失败模式,这可以在治疗方法中考虑。
OBJECTIVE: Sinonasal malignancies are a rare group of head and neck cancers. We aimed to report the oncological outcomes based on histological types in patients who underwent radiotherapy.
METHODS: In this single-institution study, we retrospectively retrieved and analyzed data of patients with sinonasal carcinomas who underwent radiotherapy during 2011-2016 as part of their treatment. The 3-year rate of local, regional, and distant recurrences, and overall survival were evaluated according to the histological type.
RESULTS: A total of 28 patients were evaluated in this study, the majority of whom were male (60%). Squamous cell carcinoma (SCC), adenoid cystic carcinoma (ACC), and adenocarcinoma (ADC) were found in 15 patients (53.5%), 8 (28.5%), and 5 (18%), respectively. The highest rates of local and regional recurrences were observed in ACC and SCC, respectively. Distant recurrences were numerically more common in ADC. The 3-year OS was 48%, 50%, and 73% in SCC, ADC, and ACC, respectively.
CONCLUSIONS: Different histopathologies of sinonasal cancer seem to have different patterns of failure, and this may be considered in the treatment approach.