未经评估:在2022年爆发期间,水痘进化枝IIb的出现与一系列其他疾病重叠。了解与痘相关的因素对临床决策很重要。
UASSIGNED:我们描述了在比利时性健康诊所寻求治疗的痘患者的特征。此外,我们将它们的特征与临床怀疑患有水痘但聚合酶链反应检测呈阴性的患者的特征进行了比较。
UNASSIGNED:在2022年5月23日至9月20日之间,有155名患者被诊断为水痘,51名怀疑症状的患者测试为阴性。所有水痘患者自我识别为男性,148/155(95.5%)为同性恋或双性恋MSM。116/155(74.8%)患者出现全身症状。除10例患者外(145/155,93.5%)均出现皮肤病变。其他表现为淋巴结肿大(72/155,46.5%),直肠炎(50/155,32.3%),尿道炎(12/155,7.7%),扁桃体炎(2/155,1.3%)。并发症包括细菌性皮肤感染(13/155,8.4%)和阴茎水肿伴或不伴副异位症(4/155,2.6%)。在多变量逻辑回归模型中,淋巴结病的存在(OR3.7995%CI1.44-11.49),皮肤病变(OR4.3595%CI1.15-17.57)和直肠炎(OR9.4195%CI2.72-47.07)与痘的诊断相关.与年龄无关,艾滋病毒状况,儿童天花疫苗接种,性伴侣和国际旅行的数量。
未经证实:直肠炎的存在,淋巴结病和皮肤病变应增加临床上对具有相容症状的患者的痘的怀疑。
UNASSIGNED: The presentation of mpox clade IIb during the 2022 outbreak overlaps with a range of other diseases. Understanding the factors associated with mpox is important for clinical decision making.
UNASSIGNED: We described the characteristics of mpox patients who sought care at Belgian sexual health clinic. Furthermore we compared their characteristics to those of patients with a clinical suspicion of mpox but who tested negative on polymerase chain reaction.
UNASSIGNED: Between May 23 and September 20, 2022, 155 patients were diagnosed with mpox, and 51 patients with suspected symptoms tested negative. All mpox patients self-identified as men and 148/155 (95.5%) as gay or bisexual MSM. Systemic symptoms were present in 116/155 (74.8%) patients. All but 10 patients (145/155, 93.5%) presented with skin lesions. Other manifestations were lymphadenopathy (72/155, 46.5%), proctitis (50/155, 32.3%), urethritis (12/155, 7.7%), tonsillitis (2/155, 1.3%). Complications involved bacterial skin infection (13/155, 8.4%) and penile oedema with or without paraphimosis (4/155, 2.6%). In multivariable logistic regression models, the presence of lymphadenopathy (OR 3.79 95% CI 1.44-11.49), skin lesions (OR 4.35 95% CI 1.15-17.57) and proctitis (OR 9.41 95% CI 2.72-47.07) were associated with the diagnosis of mpox. There were no associations with age, HIV status, childhood smallpox vaccination, number of sexual partners and international travel.
UNASSIGNED: The presence of proctitis, lymphadenopathies and skin lesions should increase clinical suspicion of mpox in patients with compatible symptoms.