血管发育不良(也称为血管扩张症)是一种以异常,胃肠道粘膜层和粘膜下层扩张的小血管。估计这些病变的活动性消化道出血发生率较低,血管发育不良的诊断具有挑战性.主动脉瓣狭窄的存在增加了血管发育不良的识别率,尤其是老年人。尽管主动脉狭窄和血管发育不良(Heyde综合征)之间的关系揭示在几个研究,Heyde综合征的病因仍有争议,这导致了本文回顾的几个假设的命题。这项活动将有助于回顾海德综合症的含义,流行病学,拟议的病理生理学,诊断,和管理通过测量1955年至2021年在PubMed上发表的文章。我们使用了诸如“结肠血管发育不良,动静脉畸形,\"\"Heyde综合征,难治性胃肠出血,主动脉瓣狭窄,“和”获得了冯·维勒布兰德病。研究结果揭示了主动脉瓣狭窄和下胃肠道(GI)出血之间的关联。
Angiodysplasia (also known as angioectasia) is a lesion characterized by abnormal, dilated small blood vessels in the mucosa and submucosal layers of the GI tract. With the estimated low incidence of active GI bleeding from these lesions, angiodysplasia can be challenging to diagnose. The presence of aortic stenosis has increased the recognition rate of angiodysplasia, especially in the elderly. Despite the associations between aortic stenosis and angiodysplasia (Heyde\'s syndrome) revealed in several studies, the etiology of Heyde syndrome is still debatable, which has led to the proposition of several hypotheses that are reviewed in this article. This activity will help review the meaning of Heyde\'s syndrome, epidemiology, proposed pathophysiology, diagnosis, and management by surveying articles published between 1955 and 2021 on PubMed. We used search terms such as \"colonic angiodysplasia,\" \"arteriovenous malformation,\" \"Heyde syndrome,\" \"refractory gastrointestinal bleed,\" \"aortic valve stenosis,\" and \"acquired von Willebrand disease.\" Findings revealed an association between aortic stenosis and lower gastrointestinal (GI) bleed.