关键词: choriocarcinoma choriocarcinoma syndrome gastrointestinal bleeding gastrointestinal neoplasms refractory gastrointestinal bleed small intestinal metastasis

来  源:   DOI:10.7759/cureus.14599   PDF(Pubmed)

Abstract:
Testicular choriocarcinomas comprise less than 1% of all testicular tumors and are often highly vascular with early hematogenous metastasis. Choriocarcinoma syndrome (CS) is a rare entity distinguished by diffuse tumor burden and often fatal bleeding from metastatic sites. Most reported cases describe pulmonary hemorrhage secondary to initiation of chemotherapy. We present a fatal case of a young, previously healthy male with overwhelming gastrointestinal bleeding as the presenting sign of CS. Our case demonstrates that CS should be considered in the differential diagnosis for refractory anemia due to gastrointestinal hemorrhage in a young male with a testicular mass.
摘要:
睾丸绒毛膜癌占所有睾丸肿瘤的不到1%,并且通常是高度血管化的,并伴有早期血行转移。绒毛膜癌综合征(CS)是一种罕见的实体,其特征是弥漫性肿瘤负荷,通常是转移部位的致命出血。大多数报道的病例描述了化疗开始继发的肺出血。我们提出了一个年轻人的致命病例,以前健康的男性,以压倒性的胃肠道出血为CS的表现。我们的病例表明,在患有睾丸肿块的年轻男性中,由于胃肠道出血引起的难治性贫血的鉴别诊断中应考虑CS。
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