■不合理用药的全球性问题,特别是关于儿科患者,是一个重大的问题。值得注意的是,在阿富汗的医疗系统中,缺乏评估儿科患者合理用药处方的研究。这项调查旨在通过在喀布尔的IndiraGandhi儿科健康研究所(IPHI)检查药物处方模式来解决这一差距,阿富汗。
■进行了前瞻性横断面分析,以评估喀布尔IPHI门诊部的现行药物处方实践,阿富汗。采用系统随机抽样的方法,从研究所选择了600张门诊处方,遵循世界卫生组织(WHO)关于医疗机构中药物使用情况的调查指南。
■患者的平均年龄为4岁,每个处方的平均药物数量为2.9。值得注意的是,84%的处方包括一种或多种抗生素,超过世界卫生组织<30%的标准。此外,67%的处方药被列入阿富汗国家基本药物清单(EDL),低于100%的标准值。只有35.1%的处方药为仿制药,也低于建议的100%。此外,所有处方的5.7%包括注射,理想值<20%。最常用的药物组是抗微生物药(25.7%),其次是非甾体抗炎药(NSAIDs),(21.4%),胃肠道药物(17.3%),和维生素(7.8%)。
■研究结果表明,平均而言,与推荐标准相比,在IPHI时,每次患者的处方数量高于推荐标准.此外,阿富汗国家基本药物清单(EDL)中的仿制药和药物利用率较低,过量的抗生素处方.
UNASSIGNED: The global issue of irrational drug use, particularly concerning pediatric patients, is a significant concern. Notably, there has been a lack of studies assessing rational drug prescribing for pediatric patients within Afghanistan\'s healthcare system. This investigation aimed to address this gap by examining drug prescribing patterns at the Indira Gandhi Pediatric Health Institute (IPHI) in Kabul, Afghanistan.
UNASSIGNED: A prospective cross-sectional analysis was conducted to evaluate the prevailing drug prescribing practices at the outpatient department of IPHI in Kabul, Afghanistan. A systematic random sampling method was employed to select 600 outpatient prescriptions from the institute, following the World Health Organization (WHO) guidelines for investigating drug utilization in healthcare facilities.
UNASSIGNED: The average age of patients was 4 years, and the average number of drugs per prescription was 2.9. Notably, 84% of prescriptions included one or more antibiotics, surpassing the WHO standard of <30%. Furthermore, 67% of the prescribed drugs were listed on Afghanistan\'s national essential drugs list (EDL), falling below the standard value of 100%. Only 35.1% of the prescribed drugs were in generic form, also lower than the recommended 100%. Moreover, 5.7% of all prescriptions included injections, the ideal value is <20%. The most frequently prescribed drug groups were anti-microbials (25.7%), followed by non-steroidal anti-inflammatory drugs (NSAIDs), (21.4%), gastrointestinal drugs (17.3%), and vitamins (7.8%).
UNASSIGNED: The study\'s findings indicate that, on average, a higher number of drugs were prescribed per patient visit at IPHI compared to recommended standards. Additionally, there was a lower utilization of generic drugs and drugs from Afghanistan\'s national essential drugs list (EDL), with an over-prescription of antibiotics.