背景:植物性脓皮病(PV)不是溃疡性结肠炎(UC)的常见肠外表现,而与UC相关的鼻粘膜PV尤其罕见。
方法:我们报告了一名28岁女性,有UC和坏疽性脓皮病病史,表现为鼻痛。在她的鼻子中可以观察到鼻腔病变,组织病理学检查指示PV。患者接受口服泼尼松(每天40mg)治疗,反应良好,无症状。随访1年后没有复发。
结论:炎症性肠病伴鼻部疼痛患者应进一步调查,以排除鼻黏膜PV共存。
BACKGROUND: Pyoderma vegetans (PV) is not a common extra-intestinal manifestation of ulcerative colitis (UC), while nasal mucosa PV associated with UC is particularly rare.
METHODS: We report a 28-year-old female with a history of UC and pyoderma gangrenosum who presented with nasal pain. A nasal lesion could be observed in her nose, and histopathological examination was indicative of PV. The patient was treated with oral prednisone (40 mg per day) with good response and became symptomatically free. There was no recurrent attack after 1 year of follow-up.
CONCLUSIONS: Inflammatory bowel disease patients presenting with nasal pain should be further investigated to rule out the coexistence of nasal mucosa PV.