pulmonary endometriosis

肺子宫内膜异位症
  • 文章类型: Case Reports
    肺子宫内膜异位症是一种发病机制不确定的罕见疾病,通常表现为月经期间计算机断层扫描发现的周期性临床症状和月经变化。我们报告了一例33岁女性反复咯血1年。患者的月经和咯血发作之间没有时间关系。胸部计算机断层扫描扫描显示右肺下叶有多个假腔,肺下叶有多个结节。行右下叶楔形切除术。术后病理检查显示为肺子宫内膜异位症,是咯血的罕见原因。
    Pulmonary endometriosis is a rare disease of uncertain pathogenesis which generally presents with the cyclic clinical symptoms and catamenial changes noticed on computer tomography during menstruation. We report a case of a 33-year-old woman with recurrent hemoptysis for 1 year. The patient did not exhibit a temporal relationship between her periods and the onset of hemoptysis. A chest computed tomography scan showed multiple pseudocavities in the lower lobe of the right lung and multiple nodules in both lower lobes of the lungs. The right lower lobe wedge resection was performed. Postoperative pathological examination showed pulmonary endometriosis which is a rare cause of hemoptysis.
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  • 文章类型: Case Reports
    肺子宫内膜异位症(PEM)罕见,药物治疗仍然是主要的治疗方法。然而,PEM患者经常会出现反复咯血,药物干预难以治疗.我们在此描述了一名PEM患者,该患者发展为复发性咯血,并在停药后成功接受光动力疗法(PDT)治疗。尽管反复药物治疗超过1年,但患者因反复咯血入院。鉴于PDT靶向特定组织并通过光敏剂的光动力反应产生的细胞毒性作用破坏血管内皮细胞,我们认为它可以有效控制PEM血管形态改变继发的咯血。因此,在这种情况下,我们进行了PDT,患者的反复咯血消退。PDT后大约2年,患者恢复良好,无不适.我们建议考虑将PDT作为停药后出现反复咯血的PEM患者的治疗选择。值得注意的是,患者的肺部病变应该是浅表的和有限的,不应该有禁忌症。
    Pulmonary endometriosis (PEM) is rare, and drug therapy remains the primary treatment. However, patients with PEM frequently experience recurrent hemoptysis that is refractory to pharmacological intervention. We herein describe a patient with PEM who developed recurrent hemoptysis and was successfully treated with photodynamic therapy (PDT) after drug withdrawal. The patient was admitted to our hospital because of recurrent hemoptysis despite repeated drug treatments for more than 1 year. Given that PDT targets specific tissues and destroys vascular endothelial cells through the cytotoxic effect produced by the photodynamic reaction of the photosensitizer, we considered that it may effectively control hemoptysis secondary to vascular morphological changes in PEM. Therefore, we performed PDT in this case, and the patient\'s recurrent hemoptysis regressed. Approximately 2 years following PDT, the patient had recovered well and reported no discomfort. We recommend consideration of PDT as a treatment option for patients with PEM who develop recurrent hemoptysis after drug withdrawal. Notably, the patient\'s lung lesions should be superficial and limited, and no contraindications should be present.
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  • 文章类型: Case Reports
    We report a case of a patient diagnosed with pulmonary endometriosis and successfully treated with a GnRH agonist. This 34-year-old mother presented cyclic hemoptysis since 4-month. A non-enhanced computed tomography made at the end of the luteal phase revealed a solitary lung nodule with no other abnormalities. A contrast enhanced computed tomography conducted during menses revealed a ground glass opacity extending from the nodule towards hilum. The diagnosis of pulmonary endometriosis was established taking into account the clinical presentation and the imaging findings. Medical treatment by Triptorelin pamoate (Decapeptyl LP® 3 mg Ipsen Pharma, France), a GnRH agonist, was proposed for a period of 6 months. A CT scan performed 3 months after the end of the treatment shows a complete disappearance of the endometriosis nodular lesion.
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  • 文章类型: Journal Article
    This study aimed to better characterize the phenomenon of catamenial pneumothorax; evaluate the risk factors, symptoms, and diagnostic modalities; and recommend treatment protocol.
    We conducted an electronic-based search using PubMed, EMBASE, Ovid MEDLINE, Google Scholar, and Cochrane Central Register of Controlled Trials.
    The following medical subject heading terms, keywords, and their combinations were used: \"catamenial pneumothorax; thoracic endometriosis; pulmonary endometriosis; and pleural endometriosis.\"
    Individual study results were tabulated in each table by outcome of interest. The search produced an initial 404 results. We excluded studies that did not contain cases with catamenial pneumothorax, case studies, and videos. Eighteen studies met our inclusion criteria and were selected, with a total of 490 patients. The prevalence of catamenial pneumothorax of all cases of pneumothorax in women of reproductive age ranges from 7.3% to 36.7%. The diagnosis was made at an older age than that of pelvic endometriosis. The presence of pelvic endometriosis was reported in only 55% of patients with catamenial pneumothorax. Previous pelvic surgeries were mentioned in only a few of the studies, and 52 of 104 cases (50%) had some kind of previous pelvic intervention. Diagnosis was mostly made clinically, with the patients complaining of the typical symptoms of shortness of breath and recurrent chest pain or shoulder pain a day before to 72 hours after menses. Pneumothorax was found mainly in the right lung (456 of 490 cases, 93%). Diaphragmatic endometriosis and/or nodules were observed in 265 of 297 cases (89%). Recurrence rate varied from 14.3% to 55%.
    The possibility of endometriosis should be considered in reproductive-aged women with catamenial symptoms of chest pain or shortness of breath. Right pneumothorax and diaphragmatic endometriosis are found in most patients.
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  • 文章类型: Case Reports
    子宫内膜异位症的肺部受累在文献中有很好的描述,但无症状的明显液气胸被认为是不寻常的表现。它通常与月经周期一致,可能是复发性疾病的原因。我们介绍了一位年轻女士,她在就业前健康筛查中被发现患有无症状的右液气胸。她来自结核病流行区,因此,我们进行了几项诊断测试来排除它。通过胸膜活检可诊断为月经性液气胸。这个案例强调了在管理不常见的演示文稿时采用系统方法的重要性。
    Pulmonary involvement in endometriosis is well described in the literature but asymptomatic significant hydropneumothorax is considered an unusual presentation. It classically coincides with a menstrual cycle and can be a cause of recurrent disease. We present a young lady who was found to have an incidental asymptomatic right hydropneumothorax on a pre-employment health screen. She comes from an endemic area of tuberculosis, thus we pursued several diagnostic tests to rule it out. A diagnosis of catamenial hydropneumothorax was reached through a pleural biopsy. This case highlights the importance of adopting a systematic approach in managing uncommon presentations.
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  • 文章类型: Case Reports
    Pulmonary endometriosis is a rare form of thoracic endometriosis. We herein describe a 29-year-old woman with recurrent hemoptysis associated with her menstrual cycle. The patient had a 4-month history of catamenial hemoptysis without thoracic pain, respiratory embarrassment, cough, fever, night sweating, or loss of appetite. Chest computed tomography revealed exudation shadows in the right lower pulmonary lobe and small fiber lesions in the right middle lobe and left lung. Thoracoscopic wedge resection of the right lower pulmonary lobe was performed, and the pathological result was pulmonary endometriosis. No evidence of hemoptysis during menstruation was found following the operation.
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  • 文章类型: Comparative Study
    To evaluate the clinical characteristics of women presenting with catamenial pneumothorax and compare them with those with noncatamenial pneumothorax.
    A case-control study (Canadian Task Force II-2).
    A multicenter study.
    Forty-two women with pneumothorax: 21 women had catamenial pneumothorax (study group), and 21 were age-matched women with noncatamenial pneumothorax (control group).
    All patients underwent video-assisted thoracoscopy and pleural biopsy. We also evaluated the presence and stage of pelvic endometriosis in 16 women with catamenial pneumothorax who had undergone laparoscopic surgery.
    The number of known episodes of catamenial pneumothorax before treatment was between 2 and 8 episodes. Symptoms were mainly chest pain and shortness of breath; 1 patient had hemoptysis. The prevalence of right-sided pneumothorax was 95.2% in the study group and 57.1% in the control group (p = .004). Besides 2 cases with complete collapse of the right lung, most of the cases in the study group had apical pneumothorax. Pelvic endometriosis was found in 15 of 16 women (93.7%), mainly stage 3 or 4, and thoracic endometriosis in 12 of 20 women (60%). None of the patients in the control group had thoracic endometriosis.
    Thoracic endometriosis is found in over half of women with catamenial pneumothorax but absent in those with noncatamenial pneumothorax. Right apical pneumothorax is predominant in women with catamenial pneumothorax. Endometriosis plays an important role in the mechanism of catamenial pneumothorax.
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  • 文章类型: Case Reports
    Pulmonary endometriosis (PEM) is a rare disease characterized by the proliferation of ectopic endometrial tissue in the lungs, which presents as catamenial hemoptysis. A 20-year-old-woman was admitted for repeated hemoptysis. Chest CT revealed a ground-glass opacity that appeared consistently with her menstrual cycle. Our detailed inquiry revealed a history of artificial abortion, which was followed by the use of oral contraceptives and catamenial hemoptysis after the discontinuation of these medications. Surgical removal was performed and histopathological examinations confirmed PEM. This clinical course suggested hematogenous metastasis. An inquiry regarding the patient\'s history of uterine procedures and use of oral contraceptives was suggestive for the diagnosis of this disease.
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  • 文章类型: Case Reports
    Pulmonary endometriosis is a gynecological disorder in which endometrial tissue grows outside of the uterine cavity. Usually, the ectopic implants are located in the pelvis and manifest as dysmenorrhea, chronic pelvic pain, or infertility. Pulmonary endometriosis sometimes occurs in the pleurae and can result in catamenial pneumothorax; however, true pulmonary endometriosis, tissue growing in the lung itself, is rare. We report a 22-year-old patient with pulmonary endometriosis and catamenial hemoptysis. Pulmonary endometriosis was proved histologically and treated successfully by wedge resection using video-assisted thoracoscopic surgery.
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  • 文章类型: Case Reports
    Thoracic endometriosis (TE) is an uncommon disorder affecting women of childbearing age. We herein report clinical and thin-section computed tomography (CT) findings of two cases, in which one woman presented with catamenial haemoptysis (CH) alone and another woman presented with bilateral catamenial pneumothoraces (CP) coinciding with CH, a rare manifestation of TE. The dynamic changes demonstrated on thin-section chest CT performed during and after menses led to accurate localisation and presumptive diagnosis of TE in both patients. Following danazol treatment, the patient with CH alone had a complete cure, while the patient with CP and CH had an incomplete cure and required long-term danazol treatment. We discuss the role of imaging studies in TE, with an emphasis on the appropriate timing and scanning technique of chest CT in women presenting with CH, potential mechanisms, treatment and patient outcomes.
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