背景:聚甲基丙烯酸甲酯(PMMA)骨水泥用于骨科和牙科以获得对骨骼的主要固定,但不能提供机械和生物学稳定的骨骼界面。因此,有很大的需求来改善PMMA骨水泥的性能以减少其临床使用限制并提高其成功率。最近的研究表明,向聚合物基材料中添加埃洛石纳米管(HNT)可以改善其机械和热特性。
目的:研究的目的是评估抗压强度,抗弯强度,最高温度,和已与7重量%HNT填料手动混合的传统PMMA骨水泥的凝固时间。
方法:将PMMA粉末和单体液体合并创建对照组,通过在液体混合之前将PMMA粉末与7重量%HNT填料混合来制备增强组。通过X射线荧光(XRF)对HNT填料进行化学表征。使用扫描电子显微镜(SEM)进行水泥的形态检查。对抗压强度进行了分析测量,抗弯强度,最高温度,和设定时间。利用独立样本t检验,对数据进行统计学评估以比较平均值(p<0.05).
结果:研究结果表明,具有7wt%HNT填料的新型增强PMMA基骨水泥显示出更高的平均抗压强度值(93MPa)和更高的弯曲强度(72MPa)。最高温度值(34.8°C)低于常规PMMA骨水泥对照组,这是(76兆帕),(51MPa),和(40°C),分别为(P<0.05)。而对照组和改良组之间的凝固时间没有显着差异。
结论:添加7wt%HNT的新型PMMA基骨水泥可有效用于骨科和牙科应用,因为它们有可能提高压缩和弯曲强度并降低最高温度。
BACKGROUND: Polymethylmethacrylate (PMMA) bone cement is used in orthopedics and dentistry to get primary fixation to bone but doesn\'t provide a mechanically and biologically stable bone interface. Therefore, there was a great demand to improve the properties of the PMMA bone cement to reduce its clinical usage limitations and enhance its success rate. Recent studies demonstrated that the addition of halloysite nanotubes (HNTs) to a polymeric-based material can improve its mechanical and thermal characteristics.
OBJECTIVE: The purpose of the study is to assess the compressive strength, flexural strength, maximum temperature, and setting time of traditional PMMA bone cements that have been manually blended with 7 wt% HNT fillers.
METHODS: PMMA powder and monomer liquid were combined to create the control group, the reinforced group was made by mixing the PMMA powder with 7 wt% HNT fillers before liquid mixing. Chemical characterization of the HNT fillers was employed by X-ray fluorescence (XRF). The morphological examination of the cements was done using a scanning electron microscope (SEM). Analytical measurements were made for the compressive strength, flexural strength, maximum temperature, and setting time. Utilizing independent sample t-tests, the data was statistically assessed to compare mean values (p < 0.05).
RESULTS: The findings demonstrated that the novel reinforced PMMA-based bone cement with 7 wt% HNT fillers showed higher mean compressive strength values (93 MPa) and higher flexural strength (72 MPa). and lower maximum temperature values (34.8 °C) than the conventional PMMA bone cement control group, which was (76 MPa), (51 MPa), and (40 °C), respectively (P < 0.05). While there was no significant difference in the setting time between the control and the modified groups.
CONCLUSIONS: The novel PMMA-based bone cement with the addition of 7 wt% HNTs can effectively be used in orthopedic and dental applications, as they have the potential to enhance the compressive and flexural strength and reduce the maximum temperatures.