背景:砂仁。是一种在全球范围内广受尊敬的药用植物。其药用特性早在唐代就有记载,尤其是水果,具有重要的药用和烹饪价值。这种植物广泛存在于亚洲的热带和亚热带地区。它具有加热中间和消除寒冷的特性,理气健脾,协调胃以减轻呕吐,和滋养不足。近年来,A.villosum因其卓越的生物活性而受到全球关注。目前,许多生物活性化合物已被成功分离和鉴定,展示了多种药理活性和药用益处。
目的:这篇综述旨在对地理分布的研究进展进行全面分析,植物学,传统应用,植物化学,药理活性,质量控制,临床应用,和A.villosum的毒理学。此外,对该植物的研究现状和未来前景进行了总结。
方法:从古代文献中获取有关A.villosum的信息,博士和硕士论文,以及包括谷歌学者在内的学术数据库,WebofScience,PubMed,中国国家知识基础设施(CNKI),ScienceDirect,植物目录,和临床报告。
结果:目前,已从A.villosum的各个器官中分离并鉴定了约500种化合物,包括单萜,倍半萜,二萜,黄酮类化合物,酚类物质,多糖,和其他组件。现代药理研究表明,山葵在体外和体内表现出特殊的生物活性,如抗炎,抗氧化剂,肝脏保护,抗肿瘤,低血糖,抗微生物,调节胃肠活动,免疫调节,调节植物区系,抗肥胖,雌激素,还有更多.这些活动中的一些已在临床实践中得到广泛应用。
结论:A.villosum,作为一种成熟的药草,具有显著的治疗潜力,也为其烹饪应用的价值。目前,对紫罗兰的活性成分或粗提物及其潜在作用机制的研究仍然有限。此外,某些药理活性需要进一步阐明,以全面了解其内部机制。此外,强烈建议优先考虑药代动力学和毒性研究。这些努力将有助于彻底探索A.villosum的潜力,并为其潜在的临床应用奠定坚实的基础。
BACKGROUND: Amomum villosum Lour. is a widely esteemed species of medicinal plant on a global scale. Its medicinal properties have been documented as early as the Tang Dynasty, particularly the fruit, which holds significant medicinal and culinary value. This plant is extensively found in tropical and subtropical regions across Asia. It possesses the properties of warming the middle and dispelling cold, regulating Qi to invigorate the spleen, harmonizing the stomach to alleviate vomiting, and nourishing deficiencies. In recent years, A. villosum has garnered global attention for its remarkable biological activity. Currently, numerous bioactive compounds have been successfully isolated and identified, showcasing a diverse array of pharmacological activities and medicinal benefits.
OBJECTIVE: This review aims to provide a comprehensive analysis of the research advancements in the geographical distribution, botany, traditional applications,
phytochemistry, pharmacological activity, quality control, clinical applications, and toxicology of A. villosum. Furthermore, a critical summary of the current research and future prospects of this plant is presented.
METHODS: Obtain information about A. villosum from ancient literature, doctoral and master\'s theses, and scholarly databases including Google Scholar, Web of Science, PubMed, China National Knowledge Infrastructure (CNKI), ScienceDirect, plant directories, and clinical reports.
RESULTS: At present, about 500 compounds have been isolated and identified from various organs of A. villosum, including monoterpenoids, sesquiterpenoids, diterpenoids, flavonoids, phenols, polysaccharides, and other components. Modern pharmacological studies have revealed that A. villosum exhibits exceptional biological activities in vitro and in vivo, such as anti-inflammatory, antioxidant, liver protection, anti-tumor, hypoglycemic, anti-microbial, regulating gastrointestinal activity, immune regulation, regulating flora, anti-obesity, estrogen, and more. Some of these activities have found extensive application in clinical practice.
CONCLUSIONS: A. villosum, as a well-established medicinal herb, holds significant therapeutic potential and is also valued for its culinary applications. Currently, the research on the active components or crude extracts of A. villosum and their potential mechanisms of action remains limited. Furthermore, certain pharmacological activities require further elucidation for a comprehensive understanding of its internal mechanisms. Moreover, it is strongly recommended to prioritize research on pharmacokinetics and toxicity studies. These efforts will facilitate a thorough exploration of the potential of A. villosum and establish a robust foundation for its potential clinical applications.