PDF(Pubmed)
Abstract：
Fritillaria unibracteata (FRU) belongs to the genus Fritillaria of the Liliaceae family. It is one of the original plants of the Chinese medicinal material \"Chuanbeimu\" and also a biological resource featured in the Tibetan Plateau of China. The dried bulbs of FRU are used in traditional Chinese medicine. The chemical constituents of FRU that have been isolated and identified include alkaloids, sterols, organic acids and their esters, nucleosides and volatile oils. FRU has antitussive, expectorant, anti-asthmatic, anti-inflammatory, antibacterial, acute lung injury-reducing, antifibrosis, antitumor, and other pharmacological effects. This valuable plant has an extremely high market demand, and over the years, due to over-exploitation, FRU has now been listed as a key species that is endangered and scarcely cultivated in China as a traditional Chinese medicinal herb. However, research on FRU is rare, and its effective components, resource control, and mechanisms of action need further study. This review systematically discusses the herbal characteristics, resource distribution, chemical composition, biosynthesis, pharmacological effects, clinical application, and breeding techniques of FRU, hoping to provide a reference for further research and the use of FRU.
摘要：
贝母（FRU）属于百合科贝母属。它是中药材“川北木”的原始植物之一，也是中国青藏高原的生物资源。FRU的干球茎用于中药。已分离和鉴定的FRU的化学成分包括生物碱，固醇,有机酸及其酯，核苷和挥发油。FRU有镇咳,祛痰药,抗哮喘,抗炎,抗菌，减少急性肺损伤，抗纤维化，抗肿瘤，和其他药理作用。这种珍贵的植物具有极高的市场需求，多年来，由于过度开发,FRU现在已被列为关键物种，在中国作为传统中草药几乎没有种植。然而,对FRU的研究很少，及其有效成分，资源控制,和作用机制需要进一步研究。这篇综述系统地讨论了中草药的特点，资源分配,化学成分,生物合成，药理作用，临床应用,和FRU的育种技术，希望为FRU的进一步研究和使用提供参考。
