peripheral aneurysm

  • 文章类型: Case Reports
    远端小脑后下动脉(PICA)动脉瘤是极为罕见的颅内动脉瘤。在破裂的急性期,干预通常涉及通过血管内治疗或直接捕获手术进行的母动脉闭塞.关于慢性破裂或未破裂动脉瘤的最佳治疗方法尚无共识。而支架辅助弹簧圈栓塞在慢性破裂阶段尚未见报道。
    我们介绍了一例46岁的女性,在蛛网膜下腔出血的初始治疗后18个月出现了远端PICA动脉瘤,并通过支架辅助线圈栓塞治疗了NeuroformAtlas(Stryker,美国),一个有利的结果。
    远端PICA动脉瘤发生在根尖弯曲处,在发育过程中存在原始动脉吻合,指出这些地点的容器壁的潜在脆弱性。支架辅助线圈栓塞术已显示出有效的保留慢性破裂和未破裂的PICA远端动脉瘤的父动脉。尽管如此,PICA的狭窄和弯曲对治疗构成障碍。在我们的案例中,利用NeuroformAtlas(Stryker,美国)采用Transcell方法。彻底掌握支架的特性及其应用对于实现有效的治疗效果至关重要。
    UNASSIGNED: Distal posterior inferior cerebellar artery (PICA) aneurysms are exceedingly rare intracranial aneurysms. In the acute phase of rupture, interventions commonly involve parent artery occlusion through endovascular treatment or direct trapping surgery. There is no consensus on the best treatment of chronic ruptured or unruptured aneurysms, and stent-assisted coil embolization has not yet been reported in the chronic phase of rupture.
    UNASSIGNED: We present a case of a 46-year-old female with a recurrent distal PICA aneurysm at 18 months following the initial treatment for subarachnoid hemorrhage and was treated by stent-assisted coil embolization with Neuroform Atlas (Stryker, USA), with a favorable outcome.
    UNASSIGNED: Distal PICA aneurysms occur at the apical curvature, where primitive arterial anastomoses existed during development, pointing to the potential vulnerability of the vessel wall at these sites. Stent-assisted coil embolization has shown effectiveness in preserving the parent artery for chronic ruptured and unruptured distal PICA aneurysms. Nonetheless, the narrowness and tortuosity of the PICA present obstacles to treatment. In our case, the procedure was feasible utilizing the Neuroform Atlas (Stryker, USA) with the Transcell approach. A thorough grasp of the characteristics of stents and their application is pivotal for achieving effective treatment outcomes.
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  • 文章类型: Journal Article
    目标:越来越多的证据强调空气污染对慢性和急性心血管疾病的影响,例如PM10与一些心血管事件之间的关联。然而,目前尚没有证据证明空气中的细微污染物对周围动脉动脉瘤的发展和进展有影响.方法:数据来自多中心PAA结果注册表POPART和德国环境署。计算每位患者手术前2、10和3650天的PM10,PM2.5,NO2和O3平均日浓度平均值。此外,对加权十年平均值进行了分析。通过计算皮尔逊相关系数来评估相关性,回归分析为多元线性或多元逻辑回归,取决于因变量。结果:对于POPART注册的1193名患者,成对的空气污染数据可用。大多数患者为男性(95.6%),并接受了开放手术修复(89.9%)。在区域层面,2000年至2022年PM10日平均值的算术平均值与平均直径和径流船只无关。发现平均PAA直径和平均NO2呈负相关,与平均O3呈正相关;然而,它们没有统计学意义。在患者层面,没有证据表明在纳入登记前10年的平均PM10暴露量与PAA直径或径流血管数量之间存在关联.经过十年的加权PM10,NO2和O3暴露也没有导致与动脉瘤直径或径流血管的显着关联。短期空气污染物浓度与有症状的PAA或围手术期并发症无关。结论:我们没有发现长期空气污染物浓度与PAA大小或严重程度相关的迹象。无论是在区域还是个人层面。此外,短期空气污染与临床表现或治疗结局无关.
    Objectives: A growing body of evidence highlights the effects of air pollution on chronic and acute cardiovascular diseases, such as associations between PM10 and several cardiovascular events. However, evidence of the impact of fine air pollutants on the development and progression of peripheral arterial aneurysms is not available. Methods: Data were obtained from the multicenter PAA outcome registry POPART and the German Environment Agency. Means of the mean daily concentration of PM10, PM2.5, NO2, and O3 concentrations were calculated for 2, 10, and 3650 days prior to surgery for each patient. Additionally, weighted ten-year averages were analyzed. Correlation was assessed by calculating Pearson correlation coefficients, and regression analyses were conducted as multiple linear or multiple logistic regression, depending on the dependent variable. Results: For 1193 patients from the POPART registry, paired air pollution data were available. Most patients were male (95.6%) and received open surgical repair (89.9%). On a regional level, the arithmetic means of the daily means of PM10 between 2000 and 2022 were neither associated with average diameters nor runoff vessels. Negative correlations for mean PAA diameter and mean NO2, as well as a positive correlation with mean O3, were found; however, they were not statistically significant. On patient level, no evidence for an association of mean PM10 exposure over ten years prior to inclusion in the registry and PAA diameter or the number of runoff vessels was found. Weighted PM10, NO2, and O3 exposure over ten years also did not result in significant associations with aneurysm diameter or runoff vessels. Short-term air pollutant concentrations were not associated with symptomatic PAAs or with perioperative complications. Conclusions: We found no indication that long-term air pollutant concentrations are associated with PAA size or severity, neither on a regional nor individual level. Additionally, short-term air pollution showed no association with clinical presentation or treatment outcomes.
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  • 文章类型: Journal Article
    背景:p动脉动脉瘤(PAAs)是最常见的外周动脉瘤。然而,由于它的稀有性,关于病人模式的累积证据,治疗策略,围手术期结局有限。该分析旨在通过对POPART(pop动脉动脉瘤修复和治疗的实践)注册表进行无监督的聚类分析,调查PAA患者的独特表型患者概况以及相关治疗和结果。
    结果:对从多中心POPART注册中心(来自德国和卢森堡的42个中心)获得的数据进行了聚类分析(使用k均值聚类)。进行敏感性分析以探讨有效性和稳定性。使用2个群集,患者主要因有无临床症状而分开.在有症状的患者群中,有急性肢体缺血表现的患者与非急诊有症状的患者之间的主要差异是PAA直径。当使用6个集群时,患者主要按合并症分组,与急性肢体缺血患者形成一个单独的集群。尽管风险状况明显不同,围手术期并发症发生率与急诊患者比例呈正相关.然而,治疗前出现任何症状的患者比例较高的集群围手术期并发症发生率较低.
    结论:所进行的分析揭示了对PAA护理的公共卫生现实以及PAA患者不良结局风险升高的洞察力。此分析表明,术前诊所是患者术前风险评估的重要辅助手段,而不是患者本身的流行病学特征。
    BACKGROUND: Popliteal artery aneurysms (PAAs) are the most common peripheral aneurysm. However, due to its rarity, the cumulative body of evidence regarding patient patterns, treatment strategies, and perioperative outcomes is limited. This analysis aims to investigate distinct phenotypical patient profiles and associated treatment and outcomes in patients with a PAA by performing an unsupervised clustering analysis of the POPART (Practice of Popliteal Artery Aneurysm Repair and Therapy) registry.
    RESULTS: A cluster analysis (using k-means clustering) was performed on data obtained from the multicenter POPART registry (42 centers from Germany and Luxembourg). Sensitivity analyses were conducted to explore validity and stability. Using 2 clusters, patients were primarily separated by the absence or presence of clinical symptoms. Within the cluster of symptomatic patients, the main difference between patients with acute limb ischemia presentation and nonemergency symptomatic patients was PAA diameter. When using 6 clusters, patients were primarily grouped by comorbidities, with patients with acute limb ischemia forming a separate cluster. Despite markedly different risk profiles, perioperative complication rates appeared to be positively associated with the proportion of emergency patients. However, clusters with a higher proportion of patients having any symptoms before treatment experienced a lower rate of perioperative complications.
    CONCLUSIONS: The conducted analyses revealed both an insight to the public health reality of PAA care as well as patients with PAA at elevated risk for adverse outcomes. This analysis suggests that the preoperative clinic is a far more crucial adjunct to the patient\'s preoperative risk assessment than the patient\'s epidemiological profile by itself.
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  • 文章类型: Journal Article
    UNASSIGNED: Traumatic popliteal pseudoaneurysms may occur in accidents or as an iatrogenic complication of a total knee arthroplasty. Complications often arise in open repair because of distorted anatomy. Up to 22% of the patients may suffer above-knee amputation. Endovascular treatment has proven to be an effective solution. However, the long-term performance of stents at the hinge point of the popliteal artery is questionable. We present a hybrid technique that was used successfully in 2 cases.
    UNASSIGNED: Our approach takes advantage of both open and endovascular techniques. At first, we apply a stent graft at the side of the injury to cover the arterial trauma and stop blood leakage to the aneurysm sac. This allows for a safer dissection and open repair. We clamp the artery proximally and distally, open the sac, extract the stent graft, and extend to a longitudinal arteriotomy. We then reconstruct the entire area with a standard in lay end-to-end anastomosis using a vein graft. This hybrid technique may reduce the risk of uncontrollable bleeding and allow for a safer nerve decompression.
    UNASSIGNED: Repair of such injuries is technically demanding. A hybrid approach may reduce the risk of complications and offer excellent long-term outcomes.
    CONCLUSIONS: The hybrid approach to the treatment of traumatic popliteal pseudoaneurysms combines the advantages of both open and endovascular approaches. It may be possible to make an acute operation just as safe as an elective operation by implementing the proposed strategy. The procedure can be performed by surgeons of all levels, and patients may benefit from a safer surgical dissection with fewer complications and blood loss. This smart combination of standard techniques may prove invaluable in a hostile surgical environment where limb loss is likely.
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  • 文章类型: Journal Article
    目的:真正的股浅动脉瘤(SFAA)很少见,传统上通过开放修复进行治疗。然而,采用覆膜支架排除动脉瘤囊的血管内途径可能是一种选择.本研究旨在比较开放和腔内修复SFAA的结果。
    方法:这是一个回顾性研究,观察,单中心研究。主要终点是:技术成功,保肢和初级通畅率,住院时间。
    结果:我们在40例患者中确定了49例SFAA;平均年龄为73.3±10.1岁,SFAA的平均直径为5.41±3.64cm,61.2%的患者有缺血或压迫相关症状。开放修复的适应症主要适用于涉及股浅动脉远端三分之一和同侧pop动脉瘤的复杂SFAA。在36名开放修复患者中,33例通过旁路或移植物介入进行结扎和血运重建,3例患者接受了简单的结扎而没有血运重建。血管内途径主要用于位于SFAA内侧三分之一的动脉瘤,其中12例患者行覆膜支架置入术,1例患者行线圈栓塞术。在所有情况下,技术成功率均为100%。在2年和4年时,两组之间的主要通畅性和保肢率没有统计学差异。开放和血管内治疗后平均住院时间为10±4和3±1天,分别。
    结论:血管内途径可能是隔离SFAA的有效替代方法,具有良好的效果和较短的住院时间。开放式维修仍然是一种有效的方法,特别是在复杂的动脉瘤中。
    OBJECTIVE: True superficial femoral artery aneurysms (SFAAs) are rare and traditionally treated by open repair. However, the endovascular approach excluding the aneurysm sac with a covered stent may be an alternative. This study aimed to compare the outcomes of the open and endovascular repair of SFAAs.
    METHODS: This is a retrospective, observational, monocentric study. The main endpoints were: technical success, limb salvage and primary patency rate, and hospitalisation time.
    RESULTS: We identified 49 SFAAs in 40 patients; the mean age was 73.3±10.1 years, the mean diameter of SFAAs was 5.41±3.64cm, and 61.2% were symptomatic for ischaemic or compression-related signs. The indication for open repair was given mainly for complex SFAAs involving the distal third of the superficial femoral artery and with an ipsilateral popliteal aneurysm. Among the 36 open-repair patients, 33 underwent ligation and revascularisation via bypass or graft interposition, and 3 patients underwent simple ligation without revascularisation. The endovascular approach was adopted mainly for aneurysms located in the medial third of the SFAA, which underwent covered stenting in 12 patients and coil embolisation in 1 patient. The technical success was 100% in all cases. There were no statistical differences in terms of primary patency and limb salvage rate between groups at two and four years. The mean hospitalisation time was 10±4 and 3±1 days after open and endovascular treatment, respectively.
    CONCLUSIONS: The endovascular approach may be a valid alternative for isolating SFAAs offering good results and shorter hospitalisation. Open repair remains a valid approach, particularly in complex aneurysms.
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  • 文章类型: Case Reports
    据报道,烟雾病患者的周围动脉瘤由于容易破裂而具有危险。高分辨率血管壁成像最近已成为评估颅内动脉瘤状态的有用方式。我们介绍了三名烟雾病患者周围动脉瘤的血管壁成像。在破裂的周围动脉瘤中观察到强烈的圆周壁增强。周围动脉瘤位于脉络膜吻合术的单个主干和多个髓支流之间的连接点。使用高分辨率血管壁成像,我们确定了烟雾病患者周围动脉瘤的特征.
    Peripheral aneurysms in patients with moyamoya disease have been reported to be hazardous owing to their rupture-prone nature. High-resolution vessel wall imaging has recently emerged as a useful modality for evaluating intracranial aneurysmal status. We present the vessel-wall imaging of peripheral aneurysms in three patients with moyamoya disease. Strong circumferential wall enhancement was observed in ruptured peripheral aneurysms. Peripheral aneurysms were located at the connection point between the single main stem and the multiple medullary tributaries of the choroidal anastomosis. Using high-resolution vessel-wall imaging, we identified the characteristics of peripheral aneurysms in patients with moyamoya disease.
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  • 文章类型: Case Reports
    我们报告了一例63岁的男子,他有2周的下肢疼痛主诉,肿胀,以及同侧膝关节化脓性关节炎发作后的低热。调查显示,the动脉动脉瘤(PAA)迅速扩大。怀疑是感染性PAA的罕见临床实体,并通过在右股pop动脉旁路术中获得的自体静脉移植物和动脉瘤囊次全切除的培养物得到证实。马链球菌被确定为主要病原体,which,据我们所知,以前没有描述过感染性PAA。
    We report the case of a 63-year-old man who presented with a 2-week complaint of lower extremity pain, swelling, and low-grade fever after an episode of septic arthritis in the ipsilateral knee. The investigation showed a rapidly expanding popliteal artery aneurysm (PAA). The rare clinical entity of an infective PAA was suspected and was confirmed by the cultures obtained at the right femoropopliteal bypass with an autologous vein graft and subtotal resection of the aneurysm sac. Streptococcus equi was identified as the primary pathogen, which, to the best of our knowledge, has not been previously described for an infective PAA.
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  • 文章类型: Journal Article
    持续性坐骨动脉是罕见的先天性异常,发病率在.01-.6%之间。虽然大多数病理患者在年轻时无症状,高达48%的患者将出现持续性坐骨动脉动脉瘤样变性,并出现跛行或下肢缺血(来自壁血栓的远端栓塞).由于持续性坐骨动脉瘤的罕见性质,病理的最佳管理尚未确定。血管内和开放技术都在这种病理的治疗中得到了描述,然而,混合管理方法的报道很少。作者介绍了一例持续性坐骨动脉瘤的病例,该病例在一名69岁的男性中成功治疗,该方法采用了股pop搭桥术(膝盖以下)。Amplatzer栓塞闭塞动脉瘤,随后切除动脉瘤。
    Persistent sciatic arteries are rare congenital abnormalities, with an incidence between .01-.6%. Whilst most patients with the pathology are asymptomatic during their younger years, up to 48% of patients will suffer aneurysmal degeneration of the persistent sciatic artery and present with claudication or lower limb ischaemia (from distal embolisation of mural thrombus). Due to the rare nature of persistent sciatic artery aneurysms, optimal management of the pathology is yet to be determined. Both endovascular and open techniques have been described in the management of this pathology, however hybrid management approaches are reported infrequently. The authors present a case of a persistent sciatic artery aneurysm successfully treated in a 69-year-old male utilising a hybrid approach with a femoropopliteal bypass (below knee), Amplatzer plug occlusion of the aneurysm and subsequent resection of the aneurysm.
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  • 文章类型: Case Reports
    周围动脉动脉瘤是最常见的类型。涉及the动脉的真菌性动脉瘤非常罕见,可以作为原发性从头感染或其他部位的继发性感染而发生。据我们所知,以前没有关于以表皮葡萄球菌为主要病原的霉菌性PAA的病例报告.我们介绍了一个55岁的男性,他抱怨下肢疼痛和肿胀,萎靡不振,和低等级温度持续两周,被发现有PAA。他接受了左股-pop旁路移植术,并进行了膨胀聚四氟乙烯(ePTFE)移植和动脉瘤结扎。术后第10天,他的下肢出现急性肿胀和疼痛,脚下垂,并在影像学上发现动脉瘤囊迅速扩大。他紧急返回手术室,通过后颅窝入路进行了动脉瘤切除术。动脉瘤囊的培养物和革兰氏染色与表皮葡萄球菌一致。如上所述,此例真菌性PAA采用标准血管外科技术治疗,然而,它继续急剧扩大。在手术干预后迅速扩张或破裂的PAA可能是感染的迹象。
    Popliteal artery aneurysms (PAAs) are the most common type of peripheral artery aneurysms. Mycotic aneurysms involving the popliteal artery are quite rare and can occur as either a primary de novo infection or a secondary infection from another site. To our knowledge, there are no previous case reports on mycotic PAA in which Staphylococcus epidermidis was the primary etiologic pathogen. We present the case of a 55-year-old male who presented with complaints of lower extremity pain and swelling, malaise, and low-grade temperatures for two weeks and was found to have a PAA. He underwent left femoral-popliteal bypass grafting with expanded polytetrafluoroethylene (ePTFE) graft and ligation of the aneurysm. On postoperative day 10, he experienced acute swelling and pain in his lower extremity with foot drop and was found to have rapid enlargement of his aneurysm sac on imaging. He was returned to the operating room emergently where he underwent aneurysmectomy via a posterior fossa approach. Cultures and gram staining of the aneurysm sac were consistent with Staphylococcus epidermidis. As noted above, this case of mycotic PAA was treated with standard vascular surgical techniques, yet it proceeded to enlarge acutely. PAAs that rapidly expand or rupture after surgical interventions may be a sign of infection.
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  • 文章类型: Case Reports
    We report the rare case of a 68-year-old man with a bilateral deep femoral artery aneurysm. Right-sided rupture was treated via plug embolization of the right deep femoral artery and ligation. In the following year, Viabahn® stent grafts were placed in the left superficial femoral artery to relieve occlusion and in the left deep femoral artery to treat the left aneurysm. The postoperative course of the patient was uneventful.
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