■了解个体卵巢激素周期及其与健康的关系,成绩和伤病对支持女运动员的从业者非常重要。静脉采血是目前测量卵巢激素的金标准,但是这种方法的侵入性在运动环境中构成了主要障碍。唾液分析可能提供一种替代方法,因为它是非侵入性的,允许“原位”收集样品,相对轻松,在应用运动环境中是必要的。
■这项研究的目的是:(i)比较毛细血管血液和唾液之间的孕酮浓度,(二)评估每周测量孕酮的功效,以确定精英足球运动员是否出现排卵,和(iii)建立唾液标准,以建立排卵和评估敏感性,该方法的特异性和准确性值。
■21个专业和半专业,西班牙联赛女子足球运动员(18.6±1.5岁,58.1±6.0kg,164.0±4.8cm),月经周期自然,完成研究。从每个参与者收集毛细管血液和唾液样品12次,每次间隔至少7天。所有的样本都是在早上采集的,经过一夜的快速。
■根据黄体期血清孕酮浓度,21名球员中有11名(52%)出现月经不调(少月经n=6,无排卵n=4,闭经n=1)。在估计的闭经组中,血浆和唾液孕酮之间存在显着相关性(r=0.80,p=<0.001,95%CI0.72-0.86)。血清和唾液孕酮之间的相关性在少月经组较弱(r=0.47,p=<0.001,95%CI0.27-0.64),在无排卵或闭经组中不存在。
■黄体酮的唾液测量值与毛细血管血密切相关,在月经期间进行,在应用运动环境中建立特征孕酮波动的非侵入性方法。缔合的强度似乎是浓度依赖性的。黄体期唾液孕酮(P4)>50pg/ml和>1.5×卵泡基线具有良好的敏感性,特异性,与已建立的血清孕酮标准相比,指示排卵的准确性。
UNASSIGNED: Understanding individual ovarian hormone cycles and their relationship with health, performance and injuries is highly important to practitioners supporting female athletes. Venous blood sampling is the current gold standard for measuring the ovarian hormones, but the invasive nature of this method presents a major barrier in sport environments. Saliva analysis may offer an alternative method as it is non-invasive, allowing the sample to be collected \"in situ\", with relative ease, necessary in applied sport environments.
UNASSIGNED: The aims of this study were: (i) To compare the concentration of progesterone between capillary blood and saliva, (ii) To assess the efficacy of weekly measurements of progesterone for determining if ovulation has occurred in elite eumenorrheic football players, and (iii) To establish a saliva criteria cut-off for establishing ovulation and assessing the sensitivity, specificity and accuracy values of the method.
UNASSIGNED: Twenty-one professional and semi-professional, Spanish league female football players (18.6 ± 1.5 years, 58.1 ± 6.0 kg, 164.0 ± 4.8 cm) with natural menstrual cycles, completed the study. Capillary blood and saliva samples were collected from each participant on twelve occasions each separated by at least 7 days. All samples were collected in the morning, following an overnight fast.
UNASSIGNED: According to luteal phase serum progesterone concentrations, 11 out of 21 (52%) players presented with menstrual irregularities (oligomenorrheic n = 6, anovulatory n = 4, amenorrhoeic n = 1). A significant correlation was observed between plasma and saliva progesterone in the estimated eumenorrheic group (r = 0.80, p = <0.001, 95% CI 0.72-0.86). The association between serum and saliva progesterone was weaker in the oligomenorrheic group (r = 0.47, p = <0.001, 95% CI 0.27-0.64) and was not present in the anovulatory or amenorrhoeic groups.
UNASSIGNED: Salivary measurements of progesterone are well correlated with capillary blood when taken during eumenorrheic menstrual cycles and presents a viable, non-invasive method of establishing characteristic progesterone fluctuations in applied sport settings. The strength of the association appears to be concentration dependent. A luteal phase saliva progesterone (P4) >50 pg/ml and >1.5× follicular baseline has good sensitivity, specificity, and accuracy to indicate ovulation compared to established criteria for serum progesterone.