■视觉系统在前庭-眼反射(VOR)的发展中起着重要作用。在临床实践中,眼前庭诱发肌源性电位(oVEMP)测试用于评估对侧VOR。
■这项研究试图比较屈光参差患者的oVEMP,斜视,和混合弱视使用单侧和双侧(同时双耳)刺激。
■检查了42例弱视患者(男性20例,女性22例),平均年龄为10.48±4.00岁(范围:5-20岁)。Titmus立体视觉测试,备用盖测试,和最佳矫正视力进行了评估。患者分为三组:屈光参差,斜视,和混合弱视。在单侧和双侧刺激下记录了oVEMP反应,包括电活动的幅度(n1-p1复合物)和VOR反应的潜伏期(n1和p1)。
■在屈光参差和斜视组中,与弱视眼相比,非弱视眼的n1潜伏期明显更快(Z=-2.04,p=0.042,Z=-2.54,p=0.024)。与斜视组的弱视眼相比,非弱视眼的平均p1潜伏期明显更快(Z=-2.31,p=0.011)。与双侧刺激相比,非弱视眼的p1潜伏期更快(所有,p<0.05)。在所有组中,n1-p1振幅在两只眼睛之间没有显着差异,在每只眼睛和双侧刺激之间(所有,p>0.05)。弱视深度与n1和p1反应之间没有发现显着相关性(所有,p>0.05)。在所有组中,弱视眼和双侧刺激之间n1和p1的潜伏期没有显着差异(所有,p>0.05)。
■无论其类型如何,弱视影响前庭眼反射反应。需要进一步研究以阐明该疾病及其治疗对眼前庭系统的影响。
UNASSIGNED: The visual system plays an important role in the development of the vestibular-ocular reflex (VOR). In clinical practice, the ocular vestibular evoked myogenic potential (
oVEMP) test is used to assess contralateral VOR.
UNASSIGNED: This study sought to compare the
oVEMP in patients with anisometropic, strabismic, and mixed amblyopia using unilateral and bilateral (simultaneous binaural) stimulation.
UNASSIGNED: Forty-two amblyopic patients (20 males and 22 females) with a mean age of 10.48 ± 4.00 years (range: 5 - 20 years) were examined. The Titmus stereopsis test, alternate cover test, and best-corrected visual acuity were evaluated. Patients were divided into three groups: anisometropic, strabismic, and mixed amblyopia. The
oVEMP responses including the amplitude of electrical activity (n1-p1 complex) and the latencies (n1 and p1) of the VOR responses were recorded under unilateral and bilateral stimulations.
UNASSIGNED: In the anisometropic and strabismic group, n1 latency was significantly faster in the non-amblyopic eyes compared to amblyopic eyes (Z = -2.04, p = 0.042, andZ = -2.54, p = 0.024 respectively). Mean p1 latency was significantly faster in the non-amblyopic eyes compared to the amblyopic eyes of the strabismic group (Z = -2.31, p = 0.011)In all groups, the p1 latency was faster in the non-amblyopic eye compared to bilateral stimulation (all, p < 0.05). In all groups, the n1-p1 amplitude was not significantly different between the two eyes, and between each eye and bilateral stimulation (all, p > 0.05). No significant correlation was found between the depth of amblyopia and n1 and p1 responses (all, p > 0.05). In all groups there was no significant difference in the latency of n1 and p1 between the amblyopic eye and bilateral stimulation (all, p > 0.05).
UNASSIGNED: Regardless of its type, amblyopia affects vestibular-ocular reflex responses. Further research is warranted to clarify the effect of the disease and its treatment on the ocular-vestibular system.