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Abstract：
UNASSIGNED: Aging is a process associated with degeneration and dysfunction of peripheral vestibular system or apparatus. This study aimed to investigate the influence of aging on ocular vestibular-evoked myogenic potential (oVEMP) response rates and recording parameters using the B81 bone vibrator and compare them with air conduction stimuli (ACS) oVEMP response characteristics.
UNASSIGNED: In 60 healthy participants aged 10-71 years (mean age 39.9; 29 male participants), the oVEMP response was elicited using a B81 bone vibrator and an ER-3A insert earphone. The effects of age and stimulus on oVEMP response rates and recording parameters were evaluated.
UNASSIGNED: Response rates and amplitudes declined with aging using either ACS or bone-conducted vibration (BCV) stimulation, particularly in individuals over 60 years of age, whereas thresholds increased and N1 latencies were prolonged. BCV showed fewer risks of absent oVEMP response than ACS (p = 0.002). BCV acquired higher amplitudes (p < 0.001), lower thresholds, and shorter N1 and P1 latencies (all p < 0.001) than ACS.
UNASSIGNED: The absence of an oVEMP response may be attributed to aging rather than a concurrent vestibular disorder. B81-BCV likely produces higher mechanical drives to the vestibular hair cells at safer and non-traumatic levels compared with ACS and therefore may be more likely to evoke a response in the elderly cohort, whose vestibular function and mechanical sensitivity have declined. Thus, B81-BCV stimulation is more effective and safer to elicit oVEMPs, and it should be recommended when ACS fails in the clinic, particularly in the elderly population.
UNASSIGNED: In 60 healthy participants aged 10-71 years (mean age 39.9; 29 male participants), the oVEMP response was elicited using a B81 bone vibrator and an ER-3A insert earphone. The effects of age and stimulus on oVEMP response rates and recording parameters were evaluated.
UNASSIGNED: Response rates and amplitudes declined with aging using either ACS or bone-conducted vibration (BCV) stimulation, particularly in individuals over 60 years of age, whereas thresholds increased and N1 latencies were prolonged. BCV showed fewer risks of absent oVEMP response than ACS (p = 0.002). BCV acquired higher amplitudes (p < 0.001), lower thresholds, and shorter N1 and P1 latencies (all p < 0.001) than ACS.
UNASSIGNED: The absence of an oVEMP response may be attributed to aging rather than a concurrent vestibular disorder. B81-BCV likely produces higher mechanical drives to the vestibular hair cells at safer and non-traumatic levels compared with ACS and therefore may be more likely to evoke a response in the elderly cohort, whose vestibular function and mechanical sensitivity have declined. Thus, B81-BCV stimulation is more effective and safer to elicit oVEMPs, and it should be recommended when ACS fails in the clinic, particularly in the elderly population.
摘要：
未经证实：衰老是与周围前庭系统或器官的退化和功能障碍相关的过程。本研究旨在使用B81骨振动器研究衰老对眼前庭诱发肌源性电位（oVEMP）反应率和记录参数的影响，并将其与空气传导刺激（ACS）oVEMP反应特征进行比较。
UNASSIGNED：在60名10-71岁的健康参与者中（平均年龄39.9岁；29名男性参与者），使用B81骨振动器和ER-3A插入式耳机引起oVEMP反应。评估了年龄和刺激对oVEMP反应率和记录参数的影响。
未经评估：使用ACS或骨传导振动（BCV）刺激，反应率和振幅随年龄增长而下降，特别是60岁以上的人，而阈值增加，N1潜伏期延长。BCV显示缺乏oVEMP反应的风险低于ACS（p=0.002）。BCV获得更高的振幅（p<0.001），较低的门槛，和较短的N1和P1延迟（所有p<0.001）比ACS。
非ASSIGNED：oVEMP反应的缺失可能归因于衰老，而不是并发的前庭障碍。与ACS相比，B81-BCV可能在更安全和非创伤性水平上对前庭毛细胞产生更高的机械驱动，因此可能更有可能在老年人群中引起反应。其前庭功能和机械敏感性下降。因此，B81-BCV刺激更有效，更安全地引发OVEMPs，应该建议当ACS在诊所失败时，尤其是老年人。
UNASSIGNED：在60名10-71岁的健康参与者中（平均年龄39.9岁；29名男性参与者），使用B81骨振动器和ER-3A插入式耳机引起oVEMP反应。评估了年龄和刺激对oVEMP反应率和记录参数的影响。
未经评估：使用ACS或骨传导振动（BCV）刺激，反应率和振幅随年龄增长而下降，特别是60岁以上的人，而阈值增加，N1潜伏期延长。BCV显示缺乏oVEMP反应的风险低于ACS（p=0.002）。BCV获得更高的振幅（p<0.001），较低的门槛，和较短的N1和P1延迟（所有p<0.001）比ACS。
非ASSIGNED：oVEMP反应的缺失可能归因于衰老，而不是并发的前庭障碍。与ACS相比，B81-BCV可能在更安全和非创伤性水平上对前庭毛细胞产生更高的机械驱动，因此可能更有可能在老年人群中引起反应。其前庭功能和机械敏感性下降。因此，B81-BCV刺激更有效，更安全地引发OVEMPs，应该建议当ACS在诊所失败时，尤其是老年人。
