■本研究旨在调查根据Bethesda甲状腺细胞病理学报告系统(TBSRTC)分类为非诊断性(ND)和非特异性意义(AUS)的甲状腺结节的超声(US)特征及其对临床管理的潜在影响。
■对2019年至2023年期间接受甲状腺结节FNAC的患者进行了回顾性研究。分析了属于ND和AUS类别的结节的美国特征,结节大小,composition,回声,形状,margin,回声病灶,美国放射学学会甲状腺成像报告和数据系统(ACRTI-RADS)类别的分布,和其他参数。该研究共包括1,199名患者和1,252个结节(ND:1110;AUS:142)。
■年龄无显著差异,性别,结节特征,回声,形状,margin,回声病灶,TI-RADS评分,本地化,结节数量,在ND和AUS类别之间发现或甲状腺实质疾病的存在(p>0.05)。此外,结节大小无统计学差异(<10mmvs.≥10mm)存在于ND和AUS类别之间(p=0.475)。两者均表现出主要的固体成分和高回声/等回声回声性。两组均观察到高比例的TI-RADS4结节,ND为727(65.5%),AUS为95(66.9%)。
■这项研究发现,ND和AUS类别之间的美国特征没有统计学上的显着差异,表明其放射学外观的潜在相似性。此外,结节大小(<10mm和≥10mm)在这些类别间无显著差异.临床管理应考虑进一步调查,包括重复FNAC,由于这两个类别的诊断挑战和恶性肿瘤风险。
UNASSIGNED: This study aimed to investigate ultrasound (US) features of thyroid nodules categorized as
nondiagnostic (ND) and atypia of undetermined significance (AUS) according to the Bethesda System for Reporting Thyroid Cytopathology (TBSRTC) and their potential implications for clinical management.
UNASSIGNED: A retrospective study was conducted on patients who underwent thyroid nodules FNAC between 2019 and 2023. Nodules falling into the ND and AUS categories were analyzed for US features, nodule size, composition, echogenicity, shape, margin, echogenic foci, the distribution of the American College of Radiology\'s Thyroid Imaging Reporting and Data System (ACR TI-RADS) categories, and other parameters. The study included a total of 1,199 patients and 1,252 nodules (ND: 1110; AUS: 142).
UNASSIGNED: No significant differences in age, gender, nodule features, echogenicity, shape, margin, echogenic foci, TI-RADS scores, localization, number of nodules, or thyroid parenchymal disease presence were found between the ND and AUS categories (p > 0.05). Also, no statistically significant difference in nodule size (<10 mm vs. ≥10 mm) existed between the ND and AUS categories (p = 0.475). Both showed predominantly solid composition and hyperechoic/isoechoic echogenicity. High proportions of TI-RADS 4 nodules were observed in both groups, with 727 (65.5%) in ND and 95 (66.9%) in AUS.
UNASSIGNED: This study found no statistically significant differences in US characteristics between the ND and AUS categories, indicating potential similarities in their radiological appearances. Also, no significant difference in nodule size (<10 mm and ≥10 mm) was observed between these categories. Clinical management should consider further investigations, including repeat FNAC, due to the diagnostic challenges and malignancy risk in both categories.