目的:脑性瘫痪(CP)是由脑损伤导致的一系列神经系统疾病的术语,损害运动功能。本研究的目的是对文献进行系统回顾,以确定与没有CP的人相比,患有CP的人是否有更高的牙周健康阴性结果风险。
方法:本研究遵循MOOSE指南的建议。在PubMed中进行了电子搜索,WebofScience,Scopus,奥维德,Embase,和PsycInfo数据库。包括评估CP患者牙周结局的观察性研究。使用纽卡斯尔-渥太华量表评估偏倚风险。进行荟萃分析,并使用标准化平均差异(SMD)呈现结果,赔率比(OR),和95%置信区间(CI)。还评估了证据的强度。
结果:总共从电子数据库中检索到316条记录,其中17个被包括在定性合成中。荟萃分析显示,与没有CP的人相比,有CP的人的口腔卫生指数得分明显更高(SMD=0.47[95%CI:0.17-0.78,I2=80%),牙龈指数(SMD=0.75[95%CI:0.39-1.11],I2=79%),菌斑指数(SMD=0.70[95%CI:0.07-1.33],I2=93%),和微积分指数(SMD=0.98[95%CI:0.76-1.20],I2=0%)。然而,牙龈炎患病率组间无显著差异(OR=1.27[95%CI:0.28-5.66],I2=93%)。结果评估和统计检验的偏倚风险较低。证据的强度被认为非常低。
结论:与没有CP的人相比,患有CP的人可能会经历更显著的牙周健康阴性结果。
OBJECTIVE: Cerebral palsy (CP) is the term for a set of neurological disorders resulting from brain damage that impairs motor function. The aim of the present study was to perform a systematic review of the literature to determine whether individuals with CP are at a greater risk of negative periodontal health outcomes compared to those without CP.
METHODS: This study followed the recommendations of the MOOSE guidelines. Electronic searches were conducted in the PubMed, Web of Science, Scopus, Ovid, Embase, and PsycInfo databases. Observational studies assessing periodontal outcomes in individuals with CP were included. Risk of bias was appraised using the Newcastle-Ottawa scale. Meta-analyses were conducted and the results were presented using standardized mean differences (SMD), odds ratios (OR), and 95% confidence intervals (CI). The strength of the evidence was also assessed.
RESULTS: A total of 316 records were retrieved from the electronic databases, 17 of which were included in the qualitative synthesis. Meta-analyses revealed significantly higher scores in individuals with CP compared to those without CP for the oral hygiene index (SMD = 0.47 [95% CI: 0.17-0.78, I2 = 80%), gingival index (SMD = 0.75 [95% CI: 0.39-1.11], I2 = 79%), plaque index (SMD = 0.70 [95% CI: 0.07-1.33], I2 = 93%), and calculus index (SMD = 0.98 [95% CI: 0.76-1.20], I2 = 0%). However, no significant difference was found between groups for the prevalence of gingivitis (OR = 1.27 [95% CI: 0.28-5.66], I2 = 93%). The risk of bias for the outcome assessment and statistical tests was low. The strength of the evidence was deemed very low.
CONCLUSIONS: Individuals with CP may experience more significant negative periodontal health outcomes compared to those without CP.