PDF(Pubmed)
Abstract：
Vitamin D binding protein (VDBP) serves as a key transporter protein responsible for binding and delivering vitamin D and its metabolites to target organs. VDBP plays a crucial part in the inflammatory reaction following tissue damage and is engaged in actin degradation. Recent research has shed light on its potential role in various diseases, leading to a growing interest in understanding the implications of VDBP in psychiatric and neurological disorders. The purpose of this review was to provide a summary of the existing understanding regarding the involvement of VDBP in neurological and psychiatric disorders. By examining the intricate interplay between VDBP and these disorders, this review contributes to a deeper understanding of underlying mechanisms and potential therapeutic avenues. Insights gained from the study of VDBP could pave the way for novel strategies in the diagnosis, prognosis, and treatment of psychiatric and neurological disorders.
摘要：
维生素D结合蛋白(VDBP)作为负责结合和递送维生素D及其代谢物至靶器官的关键转运蛋白。VDBP在组织损伤后的炎症反应中起着至关重要的作用，并参与肌动蛋白降解。最近的研究揭示了它在各种疾病中的潜在作用，导致人们对了解VDBP在精神和神经系统疾病中的意义越来越感兴趣。这篇综述的目的是提供有关VDBP参与神经和精神疾病的现有理解的摘要。通过检查VDBP和这些疾病之间复杂的相互作用，这篇综述有助于更深入地了解潜在的机制和潜在的治疗途径.从VDBP的研究中获得的见解可以为诊断的新策略铺平道路，预后,以及治疗精神和神经系统疾病。
