necrotizing granulomatous inflammation

  • 文章类型: Journal Article
    肾移植无疑是终末期肾病患者的有效治疗手段,但这肯定不是治愈方法。患者需要终生免疫抑制以维持最佳的同种异体移植功能,术后风险并发症如移植受者的癌症不容忽视。此外,感染是移植后的无症状并发症。相关地,在这里,我们报道了一名40岁的患者,他接受了肾移植,迅速发展为肝脏弥漫性大B细胞瘤和气管曲霉菌感染.此外,在肌肉中还观察到炎性坏死性肉芽肿。重要的是,我们还描述了18F-FDG-PET/CT的潜力,这有助于监测和评估这种罕见病例中这些相关的术后并发症。
    Renal transplantation is undoubtedly an effective treatment for patients with end-stage renal disease, but it is certainly not a cure. Patients require lifelong immunosuppression to maintain optimal allograft function, and post-operative risk complications such as cancer in the transplant recipient cannot be ignored. Besides, infection is a silent complication that follows transplantation. Relatedly, herein, we present a report of a 40-year-old patient who underwent renal transplantation and promptly developed a diffuse large B-cell tumor in the liver and Aspergillus infection in the trachea. In addition, an inflammatory necrotizing granuloma was also observed in the muscles. Of importance, we also described the potential of 18F-FDG-PET/CT, which was instrumental in monitoring and evaluating these relevant post-operative complications in this rare case.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Case Reports
    同时发生的结核分枝杆菌(MTB)影响肺和腹部内脏是相当普遍的,但孤立性肝结核(TB)的实例没有并发结核病的临床症状是非常罕见的。
    方法:我们介绍一例55岁女性主诉腹痛,减肥,发烧和排便习惯的改变。通过显微镜检查明确诊断为肝结核,显示坏死性肉芽肿性炎症伴有干酪样坏死。患者接受抗结核治疗,随访期间未出现任何明显的副作用。
    无活动性肺结核的肝结核非常罕见。病人出现腹痛,发烧,体重减轻和黄疸。诊断过程包括CT(计算机断层扫描)成像和随后的活检以在组织病理学上确认。按照同样的方法,我们对显示为肝结核的靶向肝病灶进行了活检.在大多数情况下,它是用抗结核药物治疗。然而,一些复杂的病例可能需要手术干预。
    结论:本病例报告强调了在结核病流行地区,考虑到结核病作为下消化道症状患者的潜在病因的重要性,强调了肝结核与肝脏孤立受累的诊断挑战。为了预防腹部结核病的严重并发症,早期诊断和及时治疗至关重要。
    UNASSIGNED: The co-occurrence of Mycobacterium tuberculosis (MTB) affecting both the lungs and abdominal viscera is quite common, but instances of isolated Hepatic tuberculosis (TB) without concurrent clinical signs of TB are exceedingly rare.
    METHODS: We present a case of a 55-year-old woman who complained of abdominal pain, weight loss, fever and changes in bowel habits. A definitive diagnosis of hepatic TB was made through microscopic examination, revealing necrotizing granulomatous inflammation accompanied by caseous necrosis. The patient received antitubercular therapy without experiencing any noticeable side effects during follow-up.
    UNASSIGNED: Hepatic TB without active pulmonary TB is quite rare case. The patient presents with abdominal pain, fever, weight loss and jaundice. The diagnostic process includes CT (computerize tomography) imaging and subsequent biopsy to confirm it histopathologically. Following the same approach, we did biopsy from the targeted hepatic lesion that showed hepatic tuberculosis. In most cases it is treated with anti-tubercular drugs. However, some complicated cases might need surgical intervention.
    CONCLUSIONS: This case report highlights the significance of considering TB into account as a potential cause in patients with lower gastrointestinal symptoms in TB endemic areas by emphasizing the diagnostic challenges posed by hepatic tuberculosis with isolated liver involvement. In order to prevent serious complications of abdominal TB, early diagnosis and timely treatment is crucial.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    结核病是印度几十年来的地方病,其在恶性肿瘤患者中的共存不容忽视。活动性感染和恶性肿瘤中2-脱氧-2-[氟-18]氟-D-葡萄糖的非特异性摄取可影响患者的诊断和治疗。然而,病变的独特解剖特征不仅有助于其定位,而且有助于诊断。我们分享了一个有趣的病例,即在治疗的宫颈癌病例中,背侧脊柱坏死性肉芽肿性炎症模仿骨骼转移。
    Tuberculosis is an endemic disease in India for decades, and its coexistence in the patients with malignancy cannot be ignored. The non-specific uptake of 2-deoxy-2-[fluorine-18] fluoro-D-glucose in active infection and malignancy can affect the diagnosis and management of patients. However, characteristic anatomical features of the lesion aid not only in its localization but also in diagnosis. We share an interesting case of necrotizing granulomatous inflammation of dorsal spine mimicking skeletal metastases in a treated case of carcinoma cervix.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

  • 文章类型: Case Reports
    Granulomatosis with polyangiitis (GPA, Wegener\'s granulomatosis) presenting as rapidly progressive glomerulonephritis is not uncommon. The recognition of multisystem disease involving joints, kidney, and lung is critical for diagnosing Wegener\'s vasculitis. Here, we report a case study of a 52-year-old Bangladeshi man presented with a history of progressively worsening fever, recurrent cough, and hemoptysis. He developed renal failure within a month which was successfully treated with high-dose steroids, cyclophosphamide, and trimethoprim-sulfamethoxazole (TMP-SMX). Rapidly progressive glomerulonephritis can be a fulminant manifestation of GPA, in which case an immediate and aggressive treatment with pulse steroids, high-dose cyclophosphamide and TMP-SMX can be lifesaving.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Case Reports
    介绍了一名73岁的肝脏坏死性肉芽肿性炎症患者。计算机断层扫描显示2例低密度肿瘤在肝脏中逐渐增强。在延迟阶段,它们几乎与正常肝实质相等。
    A 73-year-old patient with necrotizing granulomatous inflammation of the liver is presented. The computed tomography demonstrated 2 hypodense tumors with progressive enhancement in the liver. They became nearly isodense to the normal hepatic parenchyma on the delayed phase.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Sci-hub)

       PDF(Pubmed)

  • 文章类型: Case Reports
    暂无摘要。
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Sci-hub)

  • DOI:
    文章类型: Case Reports
    Nodular sclerosing Hodgkin\'s lymphoma commonly presents with a mediastinal mass, but it rarely compresses or invades mediastinal structures or the anterior chest wall. Histologically, it can cause necrotizing granulomatous inflammation. A woman with a right breast mass extending from an asymptomatic large mediastinal mass selectively compressing the trachea is presented. A computed tomography-guided core needle biopsy from the anterior chest wall mass revealed necrotizing granulomatous inflammation. Finally, the diagnosis of nodular sclerosing Hodgkin\'s lymphoma was made by incisional biopsy. Clinical suspicion of nodular sclerosing Hodgkin\'s lymphoma is crucial since an adequate tissue diagnosis is needed when the initial less invasive diagnostic testing is inconclusive.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

公众号