关键词: 18F-FDG Aspergillus tracheobronchitis complications necrotizing granulomatous inflammation post-renal transplant

来  源:   DOI:10.3389/fmed.2024.1353466   PDF(Pubmed)

Abstract:
Renal transplantation is undoubtedly an effective treatment for patients with end-stage renal disease, but it is certainly not a cure. Patients require lifelong immunosuppression to maintain optimal allograft function, and post-operative risk complications such as cancer in the transplant recipient cannot be ignored. Besides, infection is a silent complication that follows transplantation. Relatedly, herein, we present a report of a 40-year-old patient who underwent renal transplantation and promptly developed a diffuse large B-cell tumor in the liver and Aspergillus infection in the trachea. In addition, an inflammatory necrotizing granuloma was also observed in the muscles. Of importance, we also described the potential of 18F-FDG-PET/CT, which was instrumental in monitoring and evaluating these relevant post-operative complications in this rare case.
摘要:
肾移植无疑是终末期肾病患者的有效治疗手段,但这肯定不是治愈方法。患者需要终生免疫抑制以维持最佳的同种异体移植功能,术后风险并发症如移植受者的癌症不容忽视。此外,感染是移植后的无症状并发症。相关地,在这里,我们报道了一名40岁的患者,他接受了肾移植,迅速发展为肝脏弥漫性大B细胞瘤和气管曲霉菌感染.此外,在肌肉中还观察到炎性坏死性肉芽肿。重要的是,我们还描述了18F-FDG-PET/CT的潜力,这有助于监测和评估这种罕见病例中这些相关的术后并发症。
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