nails

指甲
  • 文章类型: Case Reports
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  • 文章类型: Journal Article
    正确诊断和治疗指尖和指甲损伤,通常在急诊室看到,至关重要。治疗不足会导致长期并发症,包括手指功能障碍和感觉障碍,指甲畸形,感染,或疼痛。这些剩余的问题可能导致患者生活质量的严重损害。本文就其诊断和治疗作一综述。
    A correct diagnosis and treatment of fingertip- and nail injuries, commonly seen in the emergency room, is crucial. Insufficient treatment can result in long-term complications, including finger dysfunction and dysaesthesia, nail deformity, infection, or pain. These remaining problems may induce severe impairment of the quality of life of the patient. This review summarises the diagnosis and treatment.
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  • 文章类型: Case Reports
    背景:在皮肤/性手术或创伤期间,异物在体内的保留是经常需要手术切除异物的事故和急诊科就诊的原因之一。然而,在某些情况下,这种异物的发现是在多年后发生的,从神经社会学的角度来看,患者略有受损。
    方法:一名76岁男性因阴囊体积增加而接受门诊泌尿外科检查。在超声波检查中,检测到来自固体物体的声学干扰,为此需要计算机断层扫描。计算机断层扫描显示会阴中存在细长的金属体。然后安排在手术室中去除异物。识别出位于脓肿异物肉芽肿内的10厘米长的不锈钢钉,并通过阴囊通道去除。四天后,由于皮瓣的最小坏死,进行了新的手术厕所。然后在接下来的一周中,患者在手术室中进行了另外三种敷料。通过次要意图进行愈合,直到获得手术伤口的完美愈合。
    结论:在感染的情况下从会阴去除异物可能具有挑战性。仔细的注意和术后的敷料对于病例的成功至关重要。
    BACKGROUND: The retention of foreign bodies inside the body during ludic/sexual procedures or for traumatism represents one of the causes of visits to accident and emergency departments that often requires surgical removal of the foreign body. However, there are cases where the discovery of such foreign bodies takes place after many years, as in patients that are slightly compromised from a neuro-sociological point of view.
    METHODS: A 76-year-old male presented to an outpatient urological examination due to an increase in scrotal volume. At the ultrasound check, an acoustic interference from a solid object was detected, for which computed tomography was requested. The computed tomography scan revealed the presence of an elongated metal body in the perineum. The removal of the foreign body in the operating theatre was then scheduled. A 10 cm long stainless-steel nail located within an abscessed foreign body granuloma was identified and removed via a scrotal access. Four days later, a new surgical toilet was performed due to minimal necrosis of the skin flaps. The patient then performed three more dressings in the operating theatre during the following week. Healing took place by secondary intention until a perfect healing of the surgical wound was obtained.
    CONCLUSIONS: Removal of foreign bodies from the perineum in case of infection can be challenging. Careful attention and postoperative dressings are crucial for the success of the case.
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  • 文章类型: Journal Article
    自1970年代以来,甲褶毛细管镜检查(NFC)在诊断风湿病如系统性硬化症中的应用已经得到了很好的证实.进一步的研究还表明,NFC可以检测非风湿性疾病,如糖尿病,青光眼,皮炎,和阿尔茨海默病。在过去的十年里,甲皱毛细血管形态变化也被报道为不健康的生活习惯的症状,如不良的饮食习惯,吸烟,睡眠剥夺,甚至心理压力,所有这些都会导致血液流动缓慢。因此,研究甲皱毛细血管的形态与生活习惯之间的关系很有可能表明不健康的状态,甚至是疾病前的状况。简单,便宜,和诸如NFC的非侵入性方法对于常规医学检查是重要且有用的。本研究从PubMed数据库的系统文献检索开始,然后是报告通过NFC检测到的形态学变化的评估的研究摘要。并全面审查NFC在临床诊断和改善不健康饮食生活方式中的效用。它总结了饮食和生活方式健康促进策略,基于NFC和其他指示健康微血管血流和内皮功能的相关测量进行评估。
    Since the 1970s, the utility of nailfold capillaroscopy (NFC) in diagnosing rheumatological disorders such as systemic sclerosis has been well established. Further studies have also shown that NFC can detect non-rheumatic diseases such as diabetes, glaucoma, dermatitis, and Alzheimer disease. In the past decade, nailfold capillary morphological changes have also been reported as symptoms of unhealthy lifestyle habits such as poor diet, smoking, sleep deprivation, and even psychological stress, all of which contribute to slow blood flow. Therefore, studying the relationships between the morphology of nailfold capillaries and lifestyle habits has a high potential to indicate unhealthy states or even pre-disease conditions. Simple, inexpensive, and non-invasive methods such as NFC are important and useful for routine medical examinations. The present study began with a systematic literature search of the PubMed database followed by a summary of studies reporting the assessment of morphological changes detected by NFC, and a comprehensive review of NFC\'s utility in clinical diagnosis and improving unhealthy dietary lifestyles. It culminates in a summary of dietary and lifestyle health promotion strategy, assessed based on NFC and other related measurements that indicate healthy microvascular blood flow and endothelial function.
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  • 文章类型: Journal Article
    人畜共患酵母菌种与人和猫的疾病发展有关。这项研究分析了猫科动物面部毛发和人类指甲中存在的酵母分枝杆菌群,并探索了潜在的种间关联。共检查了118份生物标本,包括59个猫科动物面部毛发和59个人类指甲样本。进行DNA提取和DNA测序以鉴定特定的酵母种类。选择人和猫中最主要的酵母菌种进行抗真菌药敏试验(伊曲康唑,酮康唑,咪康唑,和特比萘芬)。研究结果揭示了猫和人类中的多种酵母种类。在猫和人类中最常见的酵母菌是马拉色菌(45.8%)和糠马拉色菌(30.5%),分别。然而,在猫中鉴定的酵母菌种与其居住在同一家庭的主人之间没有检测到显著的相关性(p>0.05)。咪康唑在猫和人类分离物中对厚皮马拉色菌和糠马拉色菌均表现出最高的最低抑制浓度(MIC)。而特比萘芬在猫和人类分离物中对大多数厚皮马拉色菌和糠马拉色菌的MIC最低。猫面部毛发和人指甲中的多种酵母种类表明人类之间可能存在交叉污染,宠物,和环境。
    Zoonotic yeast species have been implicated in disease development in both humans and cats. This study analyzed the yeast mycobiota present in feline facial hair and human nails and explored potential interspecies associations. A total of 118 biological specimens were examined, including 59 feline facial hair and 59 human nail samples. DNA extraction and DNA sequencing were performed to identify the specific yeast species. The most predominant yeast species in humans and cats were selected for antifungal susceptibility testing (itraconazole, ketoconazole, miconazole, and terbinafine). The findings unveiled diverse yeast species in cats and humans. Malassezia pachydermatis (45.8%) and Malassezia furfur (30.5%) were the most common yeast species in cats and humans, respectively. However, no significant correlation was detected between the yeast species identified in cats and their owners residing in the same household (p > 0.05). Miconazole exhibited the highest minimum inhibitory concentrations (MICs) against Malassezia pachydermatis and Malassezia furfur in both cat and human isolates, whereas terbinafine showed the lowest MICs against most Malassezia pachydermatis and Malassezia furfur in both cat and human isolates. Diverse yeast species in cat facial hair and human nails suggest possible cross-contamination among humans, pets, and environments.
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  • 文章类型: Letter
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  • 文章类型: Journal Article
    指甲是一种角质化基质,已被提议作为头发的替代品,以评估长期和回顾性的滥用药物和药物的消耗。这个矩阵近年来越来越受到人们的关注,新的研究重点是分析不同物质的指甲和/或脚趾甲。然而,指甲和头发在结构上存在差异,增长,以及可能影响药物掺入和分析并使结果解释复杂化的掺入途径。为了更好地了解指甲样本的结果,在头发中发现的浓度比较,手指甲,和脚趾甲已经在文献中描述了一些药物。这篇综述结合了文献中的结果,对报告来自同一个体的配对样本的研究特别感兴趣。手指甲和脚趾甲样品之间的差异,以及拟议的指甲切割,也讨论了。对于某些药物可以得出明确的结论,但是,总的来说,需要更多的标准化研究来更好地了解指甲结果.
    Nails are a keratinized matrix that has been proposed as an alternative to hair to evaluate long-term and retrospective consumption of drugs of abuse and pharmaceuticals. This matrix has been gaining interest in recent years, with new studies focusing on the analysis of fingernails and/or toenails for different substances. However, nails and hair present differences in structure, growth, and incorporation pathways that may affect drug incorporation and analysis and complicate the interpretation of the results. To better understand the results in nail samples, a comparison of concentrations found in hair, fingernails, and toenails has been described in the literature for some drugs. This review unifies the results found in the literature, with special interest on studies that report paired samples from the same individuals. Differences between fingernail and toenail samples, as well as proposed cut-offs in nails, are also discussed. Definite conclusions can be reached for some drugs, but, in general, more standardized studies are needed to better understand nail results.
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  • 文章类型: Journal Article
    指甲牛皮癣是一种慢性,难以治疗的炎症,与更严重的牛皮癣有关,并可能与焦虑和显著的生活质量功能损害有关。据报道,1064nmNd:YAG激光在治疗指甲牛皮癣方面取得了令人满意的效果。该研究的目的是评估长脉冲1064nmNd:YAG激光治疗指甲牛皮癣的临床和超声疗效,并比较其与控制指甲的效果。这项患者内部随机对照试验分析了从13名患有皮肤和指甲牛皮癣的患者中收集的86个指甲。将指甲随机分为两组。A组采用Nd:YAG激光治疗,每月一次,共三个疗程,而B组作为对照组。评估是在基线进行的,最后一次治疗后1和3个月。为了得分,使用32分目标NAPSI评分系统.此外,两名失明的皮肤科医生评分改善,所有患者均通过视觉模拟评分和超声检查进行疼痛评估.在后续行动结束时,tNAPSI得分的中位数,板定义,基体厚度,与基线相比,Nd:YAG激光治疗组的床层厚度和床层血管分布显著下降(分别为p=0.001,0.006,0.039,<0.001和0.010).同时,对照组末次随访时tNAPSI评分中位数无显著降低,然而,超声记录板定义的中位数显着降低,从基线开始,床层厚度和血管分布(分别为p=0.002、0.011和0.033)。Nd:YAG激光和对照组的比较显示tNAPSI的中位数与基线没有显着差异,tNAPSI百分位数改进,凹坑计数,照片和超声评估的盲法评估。总之,Nd:YAG激光显示指甲银屑病的临床和超声改善。超声检查是诊断和监测指甲牛皮癣临床甚至亚临床变化的有用非侵入性工具。指甲牛皮癣虽然难以治疗,可能表现出自发的改善。
    Nail psoriasis is a chronic, inflammatory condition which is difficult to treat, linked with greater psoriasis severity, and may be associated with anxiety and significant functional impairment of the quality of life. The 1064 nm Nd: YAG laser was reported to yield satisfactory results in the treatment of nail psoriasis.The aim of the study was to assess the clinical and ultrasonographic efficacy of long-pulsed 1064 nm Nd: YAG laser in the treatment of fingernail psoriasis and compare its effect to control fingernails.This intra-patient randomized controlled trial analyzed 86 fingernails collected from 13 patients suffering from cutaneous and nail psoriasis. The nails were randomized into two groups. Group A was treated with Nd: YAG laser once monthly for three sessions while group B served as control. Assessment took place at baseline, 1 and 3 months after the last treatment session. For scoring, the 32-points target NAPSI scoring systems was used. Additionally, two blinded dermatologists\' score of improvement, patients\' pain assessment by visual analogue score and ultrasonographic assessment were all performed.At the end of follow up, the medians of tNAPSI score, plate definition, matrix thickness, bed thickness and bed vascularity decreased significantly in the Nd: YAG laser treated group in comparison to baseline (p = 0.001, 0.006, 0.039, < 0.001 and 0.010, respectively). While, there was a non-significant reduction in median tNAPSI score in the control group at last follow up, however, ultrasonography recorded a significant reduction in the medians of plate definition, bed thickness and vascularity (p = 0.002, 0.011 and 0.033, respectively) from the baseline. Comparison of the Nd: YAG laser and the control groups showed no significant difference from baseline regarding the medians of tNAPSI, tNAPSI percentile improvement, pits count, blinded evaluation of photographs and ultrasonographic assessments.In conclusion, Nd: YAG laser showed clinical and ultrasonographic improvement in fingernail psoriasis. Ultrasonography is a useful noninvasive tool in diagnosing and monitoring the clinical and even the subclinical changes in nail psoriasis. Nail psoriasis although difficult to treat, may show spontaneous improvement.
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  • 文章类型: Case Reports
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  • 文章类型: Journal Article
    背景:内胎趾甲是一种常见的病理。尽管一系列保守和手术措施被广泛用于这种情况,人们对它们在实践中的使用知之甚少。这项研究探索了英国足病医生对向内生长的脚趾甲的治疗或管理的现行做法。
    方法:横断面在线调查(Qualtrics,普罗沃,UT,USA)于2020年3月至6月之间进行,分发给在英国治疗或管理向内生长的脚趾甲的执业足病医生。
    结果:共有396名执业足病医生做出了回应(私营部门占60.1%)。大多数(88.6%)最常见的是(54.3%)每月少于5次进行指甲手术。几乎所有(95%)仅进行了有或没有化学基质切除术的指甲撕脱,普遍使用苯酚(97.2%)。施用时间和施用次数不同,但最通常施用三次(61.5%),共3分钟(75%)。公共部门和私营部门的善后护理差异很大,公共部门提供的后续任命较少。
    结论:尽管整个治疗途径的临床实践存在差异,几乎所有受访者都提供了苯酚基质切除术的指甲撕脱伤,而很少有人提供切开的指甲手术。此数据提供了英国足病医生如何进行甲癣的指甲手术的最全面描述。
    BACKGROUND: Ingrown toenails are a common pathology. Although a range of conservative and surgical measures are widely used for this condition, little is known about their use in practice. This study explored current practice relating to the treatment or management of ingrown toenails by podiatrists in the UK.
    METHODS: A cross-sectional online survey (Qualtrics, Provo, UT, USA) conducted between March to June 2020 was distributed to practicing podiatrists treating or managing ingrown toenails in the UK.
    RESULTS: A total of 396 practicing podiatrists responded (60.1% based in the private sector). The majority (88.6%) performed nail surgery most commonly (54.3%) less than five a month. Nearly all (95%) only performed nail avulsion with or without chemical matrixectomy, universally using phenol (97.2%). Application time and number of applications varied but was most commonly applied three times (61.5%) for a total of 3 minutes (75%). Aftercare varied considerably between public and private sectors, with public sectors offering fewer follow-up appointments.
    CONCLUSIONS: Although there is a variation in clinical practice throughout the treatment pathway, almost all respondents offered nail avulsion with phenol matrixectomy, whereas very few provided incisional nail surgery. This data provides the most comprehensive description of how UK podiatrists conduct nail surgery for onychocryptosis.
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